Making Anti-de Sitter Black Holes

It is known from the work of Banados et al. that a space-time with event horizons (much like the Schwarzschild black hole) can be obtained from 2+1 dimensional anti-de Sitter space through a suitable identification of points. We point out that this can be done in 3+1 dimensions as well. In this way we obtain black holes with event horizons that are tori or Riemann surfaces of genus higher than one. They can have either one or two asymptotic regions. Locally, the space-time is isometric to anti-de Sitter space.Comment: LaTeX, 10 pages, 6 postscript figures, uses epsf.te

Numerical Bifurcation Analysis of Conformal Formulations of the Einstein Constraints

The Einstein constraint equations have been the subject of study for more than fifty years. The introduction of the conformal method in the 1970's as a parameterization of initial data for the Einstein equations led to increased interest in the development of a complete solution theory for the constraints, with the theory for constant mean curvature (CMC) spatial slices and closed manifolds completely developed by 1995. The first general non-CMC existence result was establish by Holst et al. in 2008, with extensions to rough data by Holst et al. in 2009, and to vacuum spacetimes by Maxwell in 2009. The non-CMC theory remains mostly open; moreover, recent work of Maxwell on specific symmetry models sheds light on fundamental non-uniqueness problems with the conformal method as a parameterization in non-CMC settings. In parallel with these mathematical developments, computational physicists have uncovered surprising behavior in numerical solutions to the extended conformal thin sandwich formulation of the Einstein constraints. In particular, numerical evidence suggests the existence of multiple solutions with a quadratic fold, and a recent analysis of a simplified model supports this conclusion. In this article, we examine this apparent bifurcation phenomena in a methodical way, using modern techniques in bifurcation theory and in numerical homotopy methods. We first review the evidence for the presence of bifurcation in the Hamiltonian constraint in the time-symmetric case. We give a brief introduction to the mathematical framework for analyzing bifurcation phenomena, and then develop the main ideas behind the construction of numerical homotopy, or path-following, methods in the analysis of bifurcation phenomena. We then apply the continuation software package AUTO to this problem, and verify the presence of the fold with homotopy-based numerical methods.Comment: 13 pages, 4 figures. Final revision for publication, added material on physical implication

A Spinning Anti-de Sitter Wormhole

We construct a 2+1 dimensional spacetime of constant curvature whose spatial topology is that of a torus with one asymptotic region attached. It is also a black hole whose event horizon spins with respect to infinity. An observer entering the hole necessarily ends up at a "singularity"; there are no inner horizons. In the construction we take the quotient of 2+1 dimensional anti-de Sitter space by a discrete group Gamma. A key part of the analysis proceeds by studying the action of Gamma on the boundary of the spacetime.Comment: Latex, 28 pages, 7 postscript figures included in text, a Latex file without figures can be found at http://vanosf.physto.se/~stefan/spinning.html Replaced with journal version, minor change

Entropy of Constant Curvature Black Holes in General Relativity

We consider the thermodynamic properties of the constant curvature black hole solution recently found by Banados. We show that it is possible to compute the entropy and the quasilocal thermodynamics of the spacetime using the Einstein-Hilbert action of General Relativity. The constant curvature black hole has some unusual properties which have not been seen in other black hole spacetimes. The entropy of the black hole is not associated with the event horizon; rather it is associated with the region between the event horizon and the observer. Further, surfaces of constant internal energy are not isotherms so the first law of thermodynamics exists only in an integral form. These properties arise from the unusual topology of the Euclidean black hole instanton.Comment: 4 pages LaTeX2e (RevTeX), 2 PostScript figures. Small corrections in the text and the reference

A modified time-of-flight method for precise determination of high speed ratios in molecular beams

Time-of-flight (TOF) is a standard experimental technique for determining, among others, the speed ratio S (velocity spread) of a molecular beam. The speed ratio is a measure for the monochromaticity of the beam and an accurate determination of S is crucial for various applications, for example, for characterising chromatic aberrations in focussing experiments related to helium microscopy or for precise measurements of surface phonons and surface structures in molecular beam scattering experiments. For both of these applications, it is desirable to have as high a speed ratio as possible. Molecular beam TOF measurements are typically performed by chopping the beam using a rotating chopper with one or more slit openings. The TOF spectra are evaluated using a standard deconvolution method. However, for higher speed ratios, this method is very sensitive to errors related to the determination of the slit width and the beam diameter. The exact sensitivity depends on the beam diameter, the number of slits, the chopper radius, and the chopper rotation frequency. We present a modified method suitable for the evaluation of TOF measurements of high speed ratio beams. The modified method is based on a systematic variation of the chopper convolution parameters so that a set of independent measurements that can be fitted with an appropriate function are obtained. We show that with this modified method, it is possible to reduce the error by typically one order of magnitude compared to the standard method

Black Holes and Causal Structure in Anti-de Sitter Isometric Spacetimes

The observation that the 2+1 dimensional BTZ black hole can be obtained as a quotient space of anti-de Sitter space leads one to ask what causal behaviour other such quotient spaces can display. In this paper we answer this question in 2+1 and 3+1 dimensions when the identification group has one generator. Among other things we find that there does not exist any 3+1 generalization of the rotating BTZ hole. However, the non-rotating generalization exists and exhibits some unexpected properties. For example, it turns out to be non-static and to possess a non-trivial apparent horizon.Comment: LaTeX, 22 pages, 10 postscript figures, uses epsf.te

Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries.

The transverse tubular system of rabbit ventricular myocytes consists of cell membrane invaginations (t-tubules) that are essential for efficient cardiac excitation-contraction coupling. In this study, we investigate how t-tubule micro-anatomy, L-type Ca(2+) channel (LCC) clustering, and allosteric activation of Na(+)/Ca(2+) exchanger by L-type Ca(2+) current affects intracellular Ca(2+) dynamics. Our model includes a realistic 3D geometry of a single t-tubule and its surrounding half-sarcomeres for rabbit ventricular myocytes. The effects of spatially distributed membrane ion-transporters (LCC, Na(+)/Ca(2+) exchanger, sarcolemmal Ca(2+) pump, and sarcolemmal Ca(2+) leak), and stationary and mobile Ca(2+) buffers (troponin C, ATP, calmodulin, and Fluo-3) are also considered. We used a coupled reaction-diffusion system to describe the spatio-temporal concentration profiles of free and buffered intracellular Ca(2+). We obtained parameters from voltage-clamp protocols of L-type Ca(2+) current and line-scan recordings of Ca(2+) concentration profiles in rabbit cells, in which the sarcoplasmic reticulum is disabled. Our model results agree with experimental measurements of global Ca(2+) transient in myocytes loaded with 50 μM Fluo-3. We found that local Ca(2+) concentrations within the cytosol and sub-sarcolemma, as well as the local trigger fluxes of Ca(2+) crossing the cell membrane, are sensitive to details of t-tubule micro-structure and membrane Ca(2+) flux distribution. The model additionally predicts that local Ca(2+) trigger fluxes are at least threefold to eightfold higher than the whole-cell Ca(2+) trigger flux. We found also that the activation of allosteric Ca(2+)-binding sites on the Na(+)/Ca(2+) exchanger could provide a mechanism for regulating global and local Ca(2+) trigger fluxes in vivo. Our studies indicate that improved structural and functional models could improve our understanding of the contributions of L-type and Na(+)/Ca(2+) exchanger fluxes to intracellular Ca(2+) dynamics

Lambda<0 Quantum Gravity in 2+1 Dimensions II: Black Hole Creation by Point Particles

Using the recently proposed formalism for Lambda<0 quantum gravity in 2+1 dimensions we study the process of black hole production in a collision of two point particles. The creation probability for a BH with a simplest topology inside the horizon is given by the Liouville theory 4-point function projected on an intermediate state. We analyze in detail the semi-classical limit of small AdS curvatures, in which the probability is dominated by the exponential of the classical Liouville action. The probability is found to be exponentially small. We then argue that the total probability of creating a horizon given by the sum of probabilities of all possible internal topologies is of order unity, so that there is no exponential suppression of the total production rate.Comment: v1: 30+1 pages, figures, v2: 34+1 pages, agruments straightened ou

An ellipsoidal mirror for focusing neutral atomic and molecular beams

Manipulation of atomic and molecular beams is essential to atom optics applications including atom lasers, atom lithography, atom interferometry and neutral atom microscopy. The manipulation of charge-neutral beams of limited polarizability, spin or excitation states remains problematic, but may be overcome by the development of novel diffractive or reflective optical elements. In this paper, we present the first experimental demonstration of atom focusing using an ellipsoidal mirror. The ellipsoidal mirror enables stigmatic off-axis focusing for the first time and we demonstrate focusing of a beam of neutral, ground-state helium atoms down to an approximately circular spot, (26.8±0.5) μm×(31.4±0.8) μm in size. The spot area is two orders of magnitude smaller than previous reflective focusing of atomic beams and is a critical milestone towards the construction of a high-intensity scanning helium microscope

Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development

Abstract Adult brain is protected from entry of drugs and toxins by specific mechanisms such as ABC (ATP-binding Cassette) efflux transporters. Little is known when these appear in human brain during development. Cellular distribution of three main ABC transporters (ABCC1, ABCG2, ABCB1) was determined at blood-brain barriers and interfaces in human embryos and fetuses in first half of gestation. Antibodies against claudin-5 and -11 and antibodies to α-fetoprotein were used to describe morphological and functional aspects of brain barriers. First exchange interfaces to be established, probably at 4–5 weeks post conception, are between brain and embryonic cerebrospinal fluid (eCSF) and between outer surface of brain anlage and primary meninx. They already exclude α-fetoprotein and are immunopositive for both claudins, ABCC1 and ABCG2. ABCB1 is detectable within a week of blood vessels first penetrating into brain parenchyma (6–7 weeks post conception). ABCC1, ABCB1 and ABCG2 are present at blood-CSF barrier in all choroid plexuses from first appearance (7 weeks post conception). Outer CSF-brain interfaces are established between 9–11 weeks post conception exhibiting immunoreactivity for all three transporters. Results provide evidence for sequential establishment of brain exchange interfaces and spatial and temporal timetable for three main ABC transporters in early human brain