Cognitive Social Psychology

Social psychology is presently dominated by cognitive theories that emphasize the importance of personal beliefs and in tellective processes as the immediate determinants of behavior. The present paper explores two areas of.research within this tra dition : (1) beliefs about the external world, and (2) beliefs about the self. The paper concludes with a brief critique of the cognitive approach to social psychology.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69030/2/10.1177_014616727700300402.pd

Progesterone Receptor Activates Msx2 Expression by Downregulating TNAP/Akp2 and Activating the Bmp Pathway in EpH4 Mouse Mammary Epithelial Cells

Previously we demonstrated that EpH4 mouse mammary epithelial cells induced the homeobox transcription factor Msx2 either when transfected with the progesterone receptor (PR) or when treated with Bmp2/4. Msx2 upregulation was unaffected by Wnt inhibitors s-FRP or Dkk1, but was inhibited by the Bmp antagonist Noggin. We therefore hypothesized that PR signaling to Msx2 acts through the Bmp receptor pathway. Herein, we confirm that transcripts for Alk2/ActR1A, a non-canonical BmpR Type I, are upregulated in mammary epithelial cells overexpressing PR (EpH4-PR). Increased phosphorylation of Smads 1,5, 8, known substrates for Alk2 and other BmpR Type I proteins, was observed as was their translocation to the nucleus in EpH4-PR cells. Analysis also showed that Tissue Non-Specific Alkaline Phosphatase (TNAP/Akp2) was also found to be downregulated in EpH4-PR cells. When an Akp2 promoter-reporter construct containing a ½PRE site was transfected into EpH4-PR cells, its expression was downregulated. Moreover, siRNA mediated knockdown of Akp2 increased both Alk2 and Msx2 expression. Collectively these data suggest that PR inhibition of Akp2 results in increased Alk2 activity, increased phosphorylation of Smads 1,5,8, and ultimately upregulation of Msx2. These studies imply that re-activation of the Akp2 gene could be helpful in downregulating aberrant Msx2 expression in PR+ breast cancers

Coupling sensor observation services and web processing services for online geoprocessing in water dam monitoring

Novel sensor technologies are rapidly emerging. They enable a monitoring and modelling of our environment in a level of detail that was not possible a few years ago. However, while the raw data produced by these sensors are useful to get a first overview, it usually needs to be post-processed and integrated with other data or models in different applications. In this paper, we present an approach for integrating several geoprocessing components in the TaMIS water dam monitoring system developed with the Wupperverband, a regional waterbody authority in Germany. The approach relies upon the OGC Web Processing Service and is tightly coupled with Sensor Observation Service instances running at the Wupperverband. Besides implementing the standardized XML-based interface, lightweight REST APIs have been developed to ease the integration with thin Web clients and other Web-based components. Using this standards-based approach, new processing facilities can be easily integrated and coupled with different observation data sources

Digital techniques in HV tests-summary of 1989 panel session

NRC publication: Ye

Chromosomal localization of the UBAP2Z and UBAP2W genes in chicken

Source/description: Ubiquitin-associated protein 2 (UBAP2) is a novel gene first isolated based on its expression in the human adrenal gland. The full-length protein encoded by this gene contains a ubiquitin-associated domain, a motif found in several proteins having connections to ubiquitin and the ubiquitination pathway. In birds, UBAP2 is represented in two copies located on the Z and W chromosomes. In the recent chicken genome sequence assembly, the GGAZ and especially the GGAW sequences were poorly represented and assembled, so additional evidence for the location of Z- and W-linked loci should help to address this situation. Here, we report the cytogenetic assignment of large-insert clones for the chicken UBAP2 genes..