Dynamic model for failures in biological systems

A dynamic model for failures in biological organisms is proposed and studied both analytically and numerically. Each cell in the organism becomes dead under sufficiently strong stress, and is then allowed to be healed with some probability. It is found that unlike the case of no healing, the organism in general does not completely break down even in the presence of noise. Revealed is the characteristic time evolution that the system tends to resist the stress longer than the system without healing, followed by sudden breakdown with some fraction of cells surviving. When the noise is weak, the critical stress beyond which the system breaks down increases rapidly as the healing parameter is raised from zero, indicative of the importance of healing in biological systems.Comment: To appear in Europhys. Let

(2,2)-Formalism of General Relativity: An Exact Solution

I discuss the (2,2)-formalism of general relativity based on the (2,2)-fibration of a generic 4-dimensional spacetime of the Lorentzian signature. In this formalism general relativity is describable as a Yang-Mills gauge theory defined on the (1+1)-dimensional base manifold, whose local gauge symmetry is the group of the diffeomorphisms of the 2-dimensional fibre manifold. After presenting the Einstein's field equations in this formalism, I solve them for spherically symmetric case to obtain the Schwarzschild solution. Then I discuss possible applications of this formalism.Comment: 2 figures included, IOP style file neede

Nano granular metallic Fe - oxygen deficient TiO2−δ_{2-\delta} composite films: A room temperature, highly carrier polarized magnetic semiconductor

Nano granular metallic iron (Fe) and titanium dioxide (TiO$_{2-\delta}$) were co-deposited on (100) lanthanum aluminate (LaAlO$_3$) substrates in a low oxygen chamber pressure using a pulsed laser ablation deposition (PLD) technique. The co-deposition of Fe and TiO$_2$ resulted in $\approx$ 10 nm metallic Fe spherical grains suspended within a TiO$_{2-\delta}$ matrix. The films show ferromagnetic behavior with a saturation magnetization of 3100 Gauss at room temperature. Our estimate of the saturation magnetization based on the size and distribution of the Fe spheres agreed well with the measured value. The film composite structure was characterized as p-type magnetic semiconductor at 300 K with a carrier density of the order of $10^{22} /{\rm cm^3}$. The hole carriers were excited at the interface between the nano granular Fe and TiO$_{2-\delta}$ matrix similar to holes excited in the metal/n-type semiconductor interface commonly observed in Metal-Oxide-Semiconductor (MOS) devices. From the large anomalous Hall effect directly observed in these films it follows that the holes at the interface were strongly spin polarized. Structure and magneto transport properties suggested that these PLD films have potential nano spintronics applications.Comment: 6 pages in Latex including 8 figure

Pilot interaction with automated airborne decision making systems

The use of advanced software engineering methods (e.g., from artificial intelligence) to aid aircraft crews in procedure selection and execution is investigated. Human problem solving in dynamic environments as effected by the human's level of knowledge of system operations is examined. Progress on the development of full scale simulation facilities is also discussed

New Hamiltonian formalism and quasi-local conservation equations of general relativity

I describe the Einstein's gravitation of 3+1 dimensional spacetimes using the (2,2) formalism without assuming isometries. In this formalism, quasi-local energy, linear momentum, and angular momentum are identified from the four Einstein's equations of the divergence-type, and are expressed geometrically in terms of the area of a two-surface and a pair of null vector fields on that surface. The associated quasi-local balance equations are spelled out, and the corresponding fluxes are found to assume the canonical form of energy-momentum flux as in standard field theories. The remaining non-divergence-type Einstein's equations turn out to be the Hamilton's equations of motion, which are derivable from the {\it non-vanishing} Hamiltonian by the variational principle. The Hamilton's equations are the evolution equations along the out-going null geodesic whose {\it affine} parameter serves as the time function. In the asymptotic region of asymptotically flat spacetimes, it is shown that the quasi-local quantities reduce to the Bondi energy, linear momentum, and angular momentum, and the corresponding fluxes become the Bondi fluxes. The quasi-local angular momentum turns out to be zero for any two-surface in the flat Minkowski spacetime. I also present a candidate for quasi-local {\it rotational} energy which agrees with the Carter's constant in the asymptotic region of the Kerr spacetime. Finally, a simple relation between energy-flux and angular momentum-flux of a generic gravitational radiation is discussed, whose existence reflects the fact that energy-flux always accompanies angular momentum-flux unless the flux is an s-wave.Comment: 36 pages, 3 figures, RevTex

Dynamic model of fiber bundles

A realistic continuous-time dynamics for fiber bundles is introduced and studied both analytically and numerically. The equation of motion reproduces known stationary-state results in the deterministic limit while the system under non-vanishing stress always breaks down in the presence of noise. Revealed in particular is the characteristic time evolution that the system tends to resist the stress for considerable time, followed by sudden complete rupture. The critical stress beyond which the complete rupture emerges is also obtained

Insights into a dinoflagellate genome through expressed sequence tag analysis

BACKGROUND: Dinoflagellates are important marine primary producers and grazers and cause toxic "red tides". These taxa are characterized by many unique features such as immense genomes, the absence of nucleosomes, and photosynthetic organelles (plastids) that have been gained and lost multiple times. We generated EST sequences from non-normalized and normalized cDNA libraries from a culture of the toxic species Alexandrium tamarense to elucidate dinoflagellate evolution. Previous analyses of these data have clarified plastid origin and here we study the gene content, annotate the ESTs, and analyze the genes that are putatively involved in DNA packaging. RESULTS: Approximately 20% of the 6,723 unique (11,171 total 3'-reads) ESTs data could be annotated using Blast searches against GenBank. Several putative dinoflagellate-specific mRNAs were identified, including one novel plastid protein. Dinoflagellate genes, similar to other eukaryotes, have a high GC-content that is reflected in the amino acid codon usage. Highly represented transcripts include histone-like (HLP) and luciferin binding proteins and several genes occur in families that encode nearly identical proteins. We also identified rare transcripts encoding a predicted protein highly similar to histone H2A.X. We speculate this histone may be retained for its role in DNA double-strand break repair. CONCLUSION: This is the most extensive collection to date of ESTs from a toxic dinoflagellate. These data will be instrumental to future research to understand the unique and complex cell biology of these organisms and for potentially identifying the genes involved in toxin production

Pilot interaction with automated airborne decision making systems

Two project areas were pursued: the intelligent cockpit and human problem solving. The first area involves an investigation of the use of advanced software engineering methods to aid aircraft crews in procedure selection and execution. The second area is focused on human problem solving in dynamic environments, particulary in terms of identification of rule-based models land alternative approaches to training and aiding. Progress in each area is discussed

Comparison of Quality and Production by Different Silage Making Methods of Barley Cultivated in the Paddy after Rice Harvest

The objective of this study was to compare whether the productivity and production cost of whole crop barley was affected by silage making methods at early bloom stage in the rice field. In nutritive value, quality and palatability of silage, baled silage making method was a little higher than that of crushed silage making. On the other hand, in terms of dry matter and total digestible nutrient (TDN) production cost, proper work capacity at about 15 ha or more was desirable when making baled silage. In this case, the estimated dry matter production cost and TDN cost per ha was US $42, US$210 in baled silage making, and US $42, US$209 in crushed silage making, respectively