Preconception Care: Concepts and Perceptions: An ethical perspective

General individual preconception care is a new strategy to improve the health of future children and their mothers –and to a lesser extent the prospective fathers’ health- through primary intervention. Improving their health through preconception care comprises two component actions. The first is to impart relevant information to prospective parents, thereby improving knowledge. The second is to modify individual behaviour based on the knowledge gained. General individual preconception care anticipates on both these components and entails risk assessment, health promotion, counselling, and interventions. Risk assessment is the systematic identification and evaluation of risk factors for so-called adverse ‘pregnancy outcomes’. Risk factors vary widely and include not taking folic acid supplements, using medication that can cause malformations or functional damage to an embryo, overweight, smoking, diabetes or having an inheritable disease. Health promotion means informing and educating couples on how to improve their health in order to improve the future child’s health, including avoiding alcohol and tobacco, and the importance of proper nutrition and exercise. Prospective parents are counselled about additional screening, diagnostic tests, and specialist consultations that may be necessary if risks are identified. Intervention refers to efforts to modify or eliminate risk factors

A 0.1-to-1.2GHz tunable 6th-order N-path channel-select filter with 0.6dB passband ripple and +7dBm blocker tolerance

Radio receivers should be robust to large out-of-band blockers with small degradation in their sensitivity. N-path mixers can be used as mixer-first receivers [1] with good linearity and RF filtering [2]. However, 1/f noise calls for large active device sizes for IF circuits and high power consumption. The 1/f noise issue can be relaxed by having RF gain. However, to avoid desensitization by large out-of-band blockers, a bandpass filter (BPF) with sharp cut-off frequency is required in front of the RF amplifiers. gm-C BPFs suffer from tight tradeoffs among DR, power consumption, Q and fc. Also, on-chip Q-enhanced LC BPFs [3] are not suitable due to low DR, large area and non-tunability. Therefore, bulky and non-tunable SAW filters are used. N-path BPFs offer high Q while their center frequency is tuned by the clock frequency [2]. Compared to gm-C filters, this technique decouples the required Q from the DR. The 4-path filter in [4] has only 2nd-order filtering and limited rejection. The order and rejection of N-path BPFs can be increased by cascading [5], but this renders a “round” passband shape. The 4th-order 4-path BPF in [6] has a “flat” passband shape and high rejection but a high NF. This work solves the noise issue of [6] while achieving the same out-of-band linearity and adding 25dB of voltage gain to relax the noise requirement of the subsequent stages

Dutch dwellings

Applying Generative Design (GD) for dwelling is not very common but it opens up the possibility to study whether GD systems can reproduce existing design typologies. Dutch dwellings as an exemplification of a design typology are analysed using the SAR methodology. Building regulations are used as input to a GD system along with the typical requirements for a family house. The results show that not all existing typologies can exactly be reproduced, but the generated designs have a remarkable resemblance with Dutch dwellings. They also demonstrate that Dutch dwelling identity is at least partially encoded in Dutch building regulations. Coding of yet unknown architectural identities requires new GD metaphors to support the architect

Pathogenic bacteria and indicator organisms for anti-microbial resistance in pork meat at retail level in The Netherlands.

Slaughter pigs and pork carcasses are often contaminated with pathogenic bacteria. Consequently raw meat on sale in retail stores may also contain these bacteria. In The Netherlands the calculated contribution by pigs to the relative occurrence of human salmonellosis in the period 1994-1998 was 25.2 % (van Pelt, 2001). Survey and monitoring data on the contamination of raw products with pathogens like Salmonella, Campylobacter, Listeria monocytogenes and Escherichia coli O157 are essential for making risk estimates, and the results of surveys carried out in 1990/2000 and 2002 are presented here. In 2002 also a surveillance of anti-microbial resistance among indicator bacteria (Escherichia coli, Enterococcus faecium/faecalis) isolated from pork meat was started. The results show that pork meat was contaminated with Salmonella in levels between 6.2 - 10.5 %, S. Typhimurium being the predominant serotype, and to a lesser extent with Campylobacter, Listeria and E. coli O157