Multiplate focusing collimator

An appartus is described for scanning relatively small near sources of penetrating radiation to obtain the energy distribution thereof, wherein a collimator assembly is interposed between a radiation source and a radiation detector. The collimator assembly has a plurality of plates aligned in parallel planes with respect to a common axis normal to their centers. All the plates have similar random distribution of apertures. All apertures on each plate are the same size. The size of respective plates, the size of the apertures of said respective plates, and the spacing between said respective plates vary precisely according to a predetermined ratio to produce radiation channels which converge to a focal point. The radiation incident to the radiation detector is maximized when the focal point and the radiation source are co-incident

Prospects for Extrasolar "Earths" in Habitable Zones

We have shown that Earth-mass planets could survive in variously restricted regions of the habitable zones (HZs) of most of a sample of nine of the 102 main-sequence exoplanetary systems confirmed by 19 November 2003. In a preliminary extrapolation of our results to the other systems, we estimate that roughly a half of these systems could have had an Earth-mass planet confined to the HZ for at least the most recent 1000 Ma. The HZ migrates outwards during the main-sequence lifetime, and so this proportion varies with stellar age. About two thirds of the systems could have such a planet confined to the HZ for at least 1000 Ma at sometime during the main-sequence lifetime. Clearly, these systems should be high on the target list for exploration for terrestrial planets. We have reached this conclusion by launching putative Earth-mass planets in various orbits and following their fate with mixed-variable symplectic and hybrid integrators. Whether the Earth-mass planets could form in the HZs of the exoplanetary systems is an urgent question that needs further study.Comment: 7 pages, 2 figure

A Case Study: Imperial Valley, California

22 pages

Neutralino-hadron scattering in the NMSSM

We provide a scan of the parameter space for neutralino-hadron scattering in the next-to-minimal supersymmetric standard model using an updated value for the strange quark sigma commutator. These results also take into account constraints from WMAP data on the relic density and new constraints from the Large Hadron Collider. We find that the resultant spin-independent cross sections are smaller in magnitude than those found in recent results obtained within the constrained minimal supersymmetric standard model, yet still great enough to feasibly allow for detection in the case of bino-like neutralinos.Comment: 4 pages 5 figure

Successful Teaching: A Practical Training Course For Bible School Teachers

A pamphlet designed to help in the preparation and presentation of Bible lessons. Chapters include The Bible School, The Teacher, The Pupil, and The Lesson.https://digitalcommons.acu.edu/crs_books/1526/thumbnail.jp

Observing the Geometry of Warped Compactification via Cosmic Inflation

Using DBI inflation as an example, we demonstrate that the detailed geometry of warped compactification can leave an imprint on the cosmic microwave background (CMB). We compute CMB observables for DBI inflation in a generic class of warped throats and find that the results (such as the sign of the tilt of the scalar perturbations and its running) depend sensitively on the precise shape of the warp factor. In particular, we analyze the warped deformed conifold and find that the results can differ from those of other warped geometries, even when these geometries approximate well the exact metric of the warped deformed conifold.Comment: 4 pages, 3 figures. v2: References and clarifications adde

Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients

Purpose: Prostate cancer growth is dependent upon androgen receptor (AR) activation, regulated via phosphorylation. Protein kinase C (PKC) is one kinase that can mediate AR phosphorylation. This study aimed to establish if AR phosphorylation by PKC is of prognostic significance. Methods: Immunohistochemistry for AR, AR phosphorylated at Ser-81 (pARS81), AR phosphorylated at Ser-578 (pARS578), PKC and phosphorylated PKC (pPKC) was performed on 90 hormone-naïve prostate cancer specimens. Protein expression was quantified using the weighted histoscore method and examined with regard to clinico-pathological factors and outcome measures; time to biochemical relapse, survival from biochemical relapse and disease-specific survival. Results: Nuclear PKC expression strongly correlated with nuclear pARS578 (c.c. 0.469, p=0.001) and cytoplasmic pARS578 (c.c. 0.426 p=0.002). High cytoplasmic and nuclear pARS578 were associated with disease-specific survival (p<0.001 and p=0.036 respectively). High nuclear PKC was associated with lower disease-specific survival when combined with high pARS578 in the cytoplasm (p=0.001) and nucleus (p=0.038). Combined high total pARS81 and total pARS578 was associated with decreased disease-specific survival (p=0.005) Conclusions: pARS578 expression is associated with poor outcome and is a potential independent prognostic marker in hormone-naïve prostate cancer. Furthermore, PKC driven AR phosphorylation may promote prostate cancer progression and provide a novel therapeutic target