Kinetics and mechanism of halogenation of aniline, p-toluidine and o-toluidine using N-chloro-p-toluene sulphonamide (CAT) under buffer conditions in ethanol -water mixtures

Abstract: Kinetics of halogenation of aniline, p-toluidine and o-toluidine have been investigated by using N- Keywords: Halogenation , CAT , Amines , Reactivity of amines Aim: The present work deals with the halogenation of aromatic amines (Aniline, o-toluidine and p-toluidine) in ethanol -water mixture by CAT. Background

Development and Validation of HPTLC Method for the Estimation of Rizatriptan Benzoate in Bulk and Tablets

A new, simple high performance thin layer chromatographic method has been proposed for the determination of rizatriptan benzoate in a tablet dosage form. The drug was separated on aluminum plates precoated with silica gel 60 F254 with dichloromethane-acetone-acetic acid 3:2:0.2(v/v/v) as mobilephase. Quantitative analysis was performed by densitometric scanning at 230 nm. The method was validated for linearity, accuracy, precision and robustness. The calibration plot was linear over the range 200-700 ng/band for rizatriptan benzoate. The method was successfully applied to the analysis of drug in bulk and marketed tablets

Effect of Chloro Substitution in Oxine on Extraction of Uranium(VI)

802-80

Synthesis and Characterization of Nonsymmetric Liquid Crystal Dimer Containing Biphenyl and Azobenzene Moiety

Calamitic liquid crystalline dimer containing azobenzene moiety and a decyloxy biphenyl linked by flexible spacers {4-[7-(4′-decyloxy-biphenyl-4-yloxy)-alkyloxy]-phenyl}-(4-decyl-phenyl)-diazene has been synthesized and characterized by spectroscopic methods. The transition temperatures and phase behaviours were studied by Differential Scanning Calorimeter (DSC) and Polarizing Optical Microscope (POM). The synthesized compounds exhibited enantiotropic liquid crystal phase with higher spacer display nematic and smectic C phases while lower spacer shows nematic and smectic A phases

Management of a patient with kommerrell's aneurysm causing tracheal and esophageal compression

Tracheal and esophageal compression is a well-recognized complication of aneurysms of the aortic arch. Most of the patients present with dysphagia and/or respiratory insufficiency. In the adult population a right-sided aortic arch is often asymptomatic unless aneurysmal disease develops. This usually occurs at the level of the take-off of an aberrant left subclavian artery and is known as a Kommerell's aneurysm.In spite of its rarity, this condition is clinically relevant because of the mortality associated with rupture, the morbidity caused by compression of mediastinal struc­tures, and the complexity of surgery. In many cases, surgical resection of the aneurysm relieves the symptoms. We present a case in which tracheal compression and bilateral vocal cord palsy caused by an aneurysm arising from Kommerrell's diverticulum .The patient developed respiratory embrassement after extubation and was subsequently treated with continue positive airway pressure (CPAP) with a favorable result

Solvent Extraction of Uranium(VI) with 8-Quinolinol in the Presence of Some Heterocyclic Nitrogen Bases

505-50

Antilithiatic activity of Hibiscus sabdariffa Linn. on ethylene glycol-induced lithiasis in rats

43-47The ethanolic extract of leaves of Hibiscus sabdariffa Linn. (EEHS) was evaluated for its antilithiatic activity in rats. Lithiasis was induced by oral administration of ethylene glycolated water (0.75 %) in adult male albino Wistar rats for 28 days. The ionic chemistry of urine was altered by ethylene glycol (EG), which elevated the urinary concentration of crucial ions, viz. calcium, phosphate, uric acid and oxalate thereby contributing to renal stone formation. The EEHS, however, significantly (P< 0.05) reduced the elevated level of these ions in urine. Also, it elevated concentration of urinary magnesium, which is considered as one of the inhibitors of crystallization. All these observations revealed that EEHS has curative effect on stone formation induced by ethylene glycol