4,258 research outputs found

    Links Between Social Support, Thwarted Belongingness, and Suicide Ideation among Lesbian, Gay, and Bisexual College Students

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    Emerging adults with a lesbian, gay, or bisexual (LGB) identity are at greater risk for engaging in suicide-related behaviors. This disparity highlights a need to elucidate specific risk and protective factors associated with suicide-related behaviors among LGB youth, which could be utilized as targets for suicide prevention efforts in this population. Informed by the interpersonal-psychological theory of suicide, the present study hypothesized that social support would be indirectly associated with decreased suicide ideation via lower thwarted belongingness. A sample of 50 emerging adults (62.0% male, 70.0% Hispanic) who identified as gay, lesbian, bisexual, questioning, or “other” orientation, with a mean age of 20.84 years (SD = 3.30 years), completed self-report assessments. Results indicated that support from both family and the LGB community were associated with lower thwarted belongingness over and above the effects of age, sex, and depressive symptoms. Indirect effects models also indicated that both family and LGB community support were associated with suicide ideation via thwarted belongingness. The results of the present study suggest that family and LGB community support may represent specific targets for reducing thwarted belongingness that could be leveraged in suicide prevention efforts for LGB emerging adults

    Suppression of Kelvon-induced decay of quantized vortices in oblate Bose-Einstein Condensates

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    We study the Kelvin mode excitations on a vortex line in a three-dimensional trapped Bose-Einstein condensate at finite temperature. Our stochastic Gross-Pitaevskii simulations show that the activation of these modes can be suppressed by tightening the confinement along the direction of the vortex line, leading to a strong suppression in the vortex decay rate as the system enters a regime of two-dimensional vortex dynamics. As the system approaches the condensation transition temperature we find that the vortex decay rate is strongly sensitive to dimensionality and temperature, observing a large enhancement for quasi-two-dimensional traps. Three-dimensional simulations of the recent vortex dipole decay experiment of Neely et al. [Phys. Rev. Lett. 104, 160401 (2010)] confirm two-dimensional vortex dynamics, and predict a dipole lifetime consistent with experimental observations and suppression of Kelvon-induced vortex decay in highly oblate condensates.Comment: 8 pages, 8 figure

    Thermal Studies on Rubidium Dinitramide

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    The present study has been carried out to investigate conflicting reports in the literature on the nature of the thermal decomposition of the energetic oxidant rubidium dinitramide in the liquid state. The techniques employed included DSC, simultaneous TG-DTA, simultaneous TG-mass spectrometry and thermomicroscopy. The measurements were supplemented by quantitative chemical analysis of the reaction products. The results showed that, following fusion at 106 °C, the overall decomposition proceeded in a single exothermic reaction stage forming a mixture of rubidium nitrate and rubidium nitrite in the molar ratio 1.2 : 1

    lHuman cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis

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    Effector-memory T cells expressing Fas (Apo-1/CD95) are switched to an apoptotic program by cross-linking with Fas-ligand (FasL). Consequently, tumors that express FasL can induce apoptosis of infiltrating Fas-positive T lymphocytes and subdue any antitumor host immune response. Since Epstein-Barr virus (EBV)-associated tumors such as Hodgkin lymphoma (HL) and nasopharyngeal carcinoma (NPC) express FasL, we determined whether EBV-specific cytotoxic T lymphocytes (EBV-CTLs) could be modified to resist this evasion strategy. We show that long-term down-modulation of Fas can be achieved in EBV-CTLs by transduction with small interfering RNA (siRNA) encoded in a retrovirus. Modified T cells resisted Fas/FasL-mediated apoptosis compared with control cells and showed minimal cleavage of the caspase3 substrate poly(ADP-ribose) polymerase (PARP) protein after Fas engagement. Prolonged Fas stimulation selected a uniformly Fas(low) and FasL resistant population. Removal of responsiveness to this single death signal had no other discernible effects on EBV-CTLs. In particular, it did not lead to their autonomous growth since the modified EBV-CTLs remained polyclonal, and their survival and proliferation retained dependence on antigen-specific stimulation and on the presence of other physiologic growth signals. EBV-CTLs with knocked down Fas should have a selective functional and survival advantage over unmodified EBV-CTLs in the presence of tumors expressing FasL and may be of value for adoptive cellular therapy. (c) 2005 by The American Society of Hematology

    Persistent current formation in a high-temperature Bose-Einstein condensate: an experimental test for c-field theory

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    Experimental stirring of a toroidally trapped Bose-Einstein condensate at high temperature generates a disordered array of quantum vortices that decays via thermal dissipation to form a macroscopic persistent current [T. W. Neely em et al. arXiv:1204.1102 (2012)]. We perform 3D numerical simulations of the experimental sequence within the Stochastic Projected Gross-Pitaevskii equation using ab initio determined reservoir parameters. We find that both damping and noise are essential for describing the dynamics of the high-temperature Bose field. The theory gives a quantitative account of the formation of a persistent current, with no fitted parameters.Comment: v2: 7 pages, 3 figures, new experimental data and numerical simulation

    Rotation symmetry axes and the quality index in a 3D octahedral parallel robot manipulator system

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    The geometry of a 3D octahedral parallel robot manipulator system is specified in terms of two rigid octahedral structures (the fixed and moving platforms) and six actuation legs. The symmetry of the system is exploited to determine the behaviour of (a new version of) the quality index for various motions. The main results are presented graphically

    Eudaimonistic Argumentation

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    Virtue theories have lately enjoyed a modest vogue in the study of argumentation, echoing the success of more far-reaching programmes in ethics and epistemology. Virtue theories of argumentation (VTA) comprise several conceptually distinct projects, including the provision of normative foundations for argument evaluation and a renewed focus on the character of good arguers. Perhaps the boldest of these is the pursuit of the fully satisfying argument, the argument that contributes to human flourishing. This project has an independently developed epistemic analogue: eudaimonistic virtue epistemology. Both projects stress the importance of widening the range of cognitive goals beyond, respectively, cogency and knowledge; both projects emphasize social factors, the right sort of community being indispensable for the cultivation of the intellectual virtues necessary to each project. This paper proposes a unification of the two projects by arguing that the intellectual good life sought by eudaimonistic virtue epistemologists is best realized through the articulation of an account of argumentation that contributes to human flourishing
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