630 research outputs found
Spin and Charge Correlations in Quantum Dots: An Exact Solution
The inclusion of charging and spin-exchange interactions within the Universal
Hamiltonian description of quantum dots is challenging as it leads to a
non-Abelian action. Here we present an {\it exact} analytical solution of the
probem, in particular, in the vicinity of the Stoner instabilty point. We
calculate several observables, including the tunneling density of states (TDOS)
and the spin susceptibility. Near the instability point the TDOS exhibits a
non-monotonous behavior as function of the tunneling energy, even at
temperatures higher than the exchange energy. Our approach is generalizable to
a broad set of observables, including the a.c. susceptibility and the
absorption spectrum for anisotropic spin interaction. Our results could be
tested in nearly ferromagnetic materials.Comment: JETPL class, 6 pages, 2 figure
Magnetic fluctuations in 2D metals close to the Stoner instability
We consider the effect of potential disorder on magnetic properties of a
two-dimensional metallic system (with conductance ) when interaction in
the triplet channel is so strong that the system is close to the threshold of
the Stoner instability. We show, that under these conditions there is an
exponentially small probability for the system to form local spin droplets
which are local regions with non zero spin density. Using a non-local version
of the optimal fluctuation method we find analytically the probability
distribution and the typical spin of a local spin droplet (LSD). In particular,
we show that both the probability to form a LSD and its typical spin are
independent of the size of the droplet (within the exponential accuracy). The
LSDs manifest themselves in temperature dependence of observable quantities. We
show, that below certain cross-over temperature the paramagnetic susceptibility
acquires the Curie-like temperature dependence, while the dephasing time
(extracted from magneto-resistance measurements) saturates.Comment: 15 pages, 4 figure
Gossip in the workplace and the implications for HR management : a study of gossip and its relationship to employee cynicism
Gossip is a common phenomenon in the workplace and yet relatively little is understood about its
influence to employees. This study adopts social information theory and social cognitive theory to interpret
the diverse literature on gossip, and to develop and test hypotheses concerning some of the antecedents of
gossip, with an aim of developing knowledge of the relationship between gossip and employee behaviour in
the workplace. The study analysed survey data in a two stage process, from 362 employees across a range
of industries in Taiwan. The findings revealed that job-related gossip predicted employee cynicism and
mediated the relationship between psychological contract violation and cynicism, and that non-job-related
gossip showed a similar but weaker effect to employee cynicism. The contribution made by this paper is of
value to both the academic subject domain and managers in Human Resources. Firstly, we have identified
two constructs of gossip, job related and non-job related gossip not previously reported and a validated scale
has been created. Secondly, we have confirmed that these different constructs of gossip impact differently on
employee behaviour and therefore HR managers should be cautious about gossip in the workplace, as it can
cause cynical behaviour amongst employees
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance.
MAF1 is a global repressor of RNA polymerase III transcription that regulates the expression of highly abundant noncoding RNAs in response to nutrient availability and cellular stress. Thus, MAF1 function is thought to be important for metabolic economy. Here we show that a whole-body knockout of Maf1 in mice confers resistance to diet-induced obesity and nonalcoholic fatty liver disease by reducing food intake and increasing metabolic inefficiency. Energy expenditure in Maf1(-/-) mice is increased by several mechanisms. Precursor tRNA synthesis was increased in multiple tissues without significant effects on mature tRNA levels, implying increased turnover in a futile tRNA cycle. Elevated futile cycling of hepatic lipids was also observed. Metabolite profiling of the liver and skeletal muscle revealed elevated levels of many amino acids and spermidine, which links the induction of autophagy in Maf1(-/-) mice with their extended life span. The increase in spermidine was accompanied by reduced levels of nicotinamide N-methyltransferase, which promotes polyamine synthesis, enables nicotinamide salvage to regenerate NAD(+), and is associated with obesity resistance. Consistent with this, NAD(+) levels were increased in muscle. The importance of MAF1 for metabolic economy reveals the potential for MAF1 modulators to protect against obesity and its harmful consequences
Orthogonality Catastrophe in Parametric Random Matrices
We study the orthogonality catastrophe due to a parametric change of the
single-particle (mean field) Hamiltonian of an ergodic system. The Hamiltonian
is modeled by a suitable random matrix ensemble. We show that the overlap
between the original and the parametrically modified many-body ground states,
, taken as Slater determinants, decreases like , where is
the number of electrons in the systems, is a numerical constant of the
order of one, and is the deformation measured in units of the typical
distance between anticrossings. We show that the statistical fluctuations of
are largely due to properties of the levels near the Fermi energy.Comment: 12 pages, 8 figure
Ronald V. Dellums v. George Bush (D.D.C. 1990): Memorandum Amicus Curiae of Law Professors
This joint memorandum is submitted to the court hearing Dellums v. Bush. This amicus brief advocates that the President may not order American armed forces to make war without consultation with and approval by Congress. The brief also argues that the case is justiciable
\u3cem\u3eRonald V. Dellums v. George Bush\u3c/em\u3e (D.D.C. 1990): Memorandum \u3cem\u3eAmicus Curiae\u3c/em\u3e of Law Professors
This joint memorandum is submitted to the court hearing Dellums v. Bush. This amicus brief advocates that the President may not order American armed forces to make war without consultation with and approval by Congress. The brief also argues that the case is justiciable
Ground-State Magnetization for Interacting Fermions in a Disordered Potential : Kinetic Energy, Exchange Interaction and Off-Diagonal Fluctuations
We study a model of interacting fermions in a disordered potential, which is
assumed to generate uniformly fluctuating interaction matrix elements. We show
that the ground state magnetization is systematically decreased by off-diagonal
fluctuations of the interaction matrix elements. This effect is neglected in
the Stoner picture of itinerant ferromagnetism in which the ground-state
magnetization is simply determined by the balance between ferromagnetic
exchange and kinetic energy, and increasing the interaction strength always
favors ferromagnetism. The physical origin of the demagnetizing effect of
interaction fluctuations is the larger number of final states available for
interaction-induced scattering in the lower spin sectors of the Hilbert space.
We analyze the energetic role played by these fluctuations in the limits of
small and large interaction . In the small limit we do second-order
perturbation theory and identify explicitly transitions which are allowed for
minimal spin and forbidden for higher spin. These transitions then on average
lower the energy of the minimal spin ground state with respect to higher spin.
For large interactions we amplify on our earlier work [Ph. Jacquod and A.D.
Stone, Phys. Rev. Lett. 84, 3938 (2000)] which showed that minimal spin is
favored due to a larger broadening of the many-body density of states in the
low-spin sectors. Numerical results are presented in both limits.Comment: 35 pages, 24 figures - final, shortened version, to appear in
Physical Review
Guillain-Barré syndrome: a century of progress
In 1916, Guillain, BarrĂ© and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts â novel findings that identified the disease we now know as GuillainâBarrĂ© syndrome (GBS). 100 years on, we have made great progress with the clinical and pathological characterization of GBS. Early clinicopathological and animal studies indicated that GBS was an immune-mediated demyelinating disorder, and that severe GBS could result in secondary axonal injury; the current treatments of plasma exchange and intravenous immunoglobulin, which were developed in the 1980s, are based on this premise. Subsequent work has, however, shown that primary axonal injury can be the underlying disease. The association of Campylobacter jejuni strains has led to confirmation that anti-ganglioside antibodies are pathogenic and that axonal GBS involves an antibody and complement-mediated disruption of nodes of Ranvier, neuromuscular junctions and other neuronal and glial membranes. Now, ongoing clinical trials of the complement inhibitor eculizumab are the first targeted immunotherapy in GBS
Advantages of dynamic âclosed loopâ stable isotope flux phenotyping over static âopen loopâ clamps in detecting silent genetic and dietary phenotypes
In vivo insulin sensitivity can be assessed using âopen loopâ clamp or âclosed loopâ methods. Open loop clamp methods are static, and fix plasma glucose independently from plasma insulin. Closed loop methods are dynamic, and assess glucose disposal in response to a stable isotope labeled glucose tolerance test. Using PPARαâ/â mice, open and closed loop assessments of insulin sensitivity/glucose disposal were compared. Indirect calorimetry done for the assessment of diurnal substrate utilization/metabolic flexibility showed that chow fed PPARαâ/â mice had increased glucose utilization during the light (starved) cycle. Euglycemic clamps showed no differences in insulin stimulated glucose disposal, whether for chow or high fat diets, but did show differences in basal glucose clearance for chow fed PPARαâ/â versus SV129J-wt mice. In contrast, the dynamic stable isotope labeled glucose tolerance tests reveal enhanced glucose disposal for PPARαâ/â versus SV129J-wt, for chow and high fat diets. Area under the curve for plasma labeled and unlabeled glucose for PPARαâ/â was â1.7-fold lower, P < 0.01 during the stable isotope labeled glucose tolerance test for both diets. Area under the curve for plasma insulin was 5-fold less for the chow fed SV129J-wt (P < 0.01) but showed no difference on a high fat diet (0.30 ± 0.1 for SV129J-wt vs. 0.13 ± 0.10 for PPARαâ/â, P = 0.28). This study demonstrates that dynamic stable isotope labeled glucose tolerance test can assess âsilentâ metabolic phenotypes, not detectable by the static, âopen loopâ, euglycemic or hyperglycemic clamps. Both open loop and closed loop methods may describe different aspects of metabolic inflexibility and insulin sensitivity
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