820 research outputs found

    Vapor Distribution above an Evaporating Sessile Drop

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    An experimental technique was developed that uses infrared tomography to measure the three-dimensional vapor distribution above an evaporating sessile drop. The technique was applied to measure the vapor distributions above evaporating drops of hexane and 3-methylpentane (3MP) at room temperature and pressure. The molecular masses of these two species are heavier than air and the vapor from the evaporating drop forms a flat, disk-shaped cloud. A Fourier transform infrared spectrometer (FTIR) was used to measure the spectral absorbance along a set of paths passing through the vapor cloud. From a set of path-averaged absorbance measurements, a two-dimensional spatial concentration distribution was determined using a computed tomography routine. A three-dimensional concentration distribution was obtained from multiple two-dimensional distributions obtained at different elevations above the drop. The vapor distributions for both hexane and 3MP differ significantly from the values predicted by the solutions for diffusion-limited evaporation and indicate the effect of buoyancy-induced convection of the vapor. These measurements are the first quantitative measurements of the vapor distribution above a sessile drop and are important for advancing the understanding of the vapor phase transport mechanisms, and thus sessile drop evaporation

    STUDY OF THE O-18+Ni-64 TWO-NEUTRON TRANSFER REACTION AT 84 MeV BY MAGNEX

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    A study of the two-neutron transfer reaction of the O-18 + Ni-64 system at 84 MeV incident energy to the ground and first 2(+) excited state of the residual Ni-66 nucleus is presented. The experiment was performed at the INFN-LNS (Italy) by using the large acceptance MAGNEX spectrometer. Theoretical models are used in order to disentangle the competition between long-range and short-range correlations

    Aeromonas no processamento de queijos tipos Minas Frescal e Colonial.

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    Resumo: Com o objetivo de estabelecer, durante o processamento do queijo Minas Frescal e Colonial os possíveis pontos de contaminação e a forma de disseminação de bactérias do gênero Aeromonas, foram analisados, quanto à presença do micro-organismo, diferentes produtos e pontos do fluxograma de produção. Para o Queijo Minas Frescal, Aeromonas spp. foram isoladas no leite cru, leite pasteurizado, ambiente de produção e nas mãos dos manipuladores. A. caviae foi a espécie mais frequentemente identificada, sendo também isoladas A. sobria e A. schubertii. Durante o processamento do queijo Colonial, as espécies A. hydrophila, A. caviae, A. sobria, A. veronii e A. jandaei foram isoladas a partir da água, mãos dos manipuladores, utensílios, leite cru e após tratamento térmico e de massa coagulada. Os resultados demonstram que o gênero Aeromonas encontra-se disseminado nas diferentes etapas do processamento de queijos, destacando-se o leite cru como principal fonte de contaminação para o processamento industrial e artesanal. [Aeromonas in processing line of Minas Frescal and Colonial cheeses]. Abstract: The aim of this study is to establish possible contamination points and dissemination forms of the bacteria genus Aeromonas during the processing of the Brazilian cheeses Minas Frescal and Colonial. Therefore, different products and production points of the process were analyzed to determine the presence of the microorganism. In Minas Frescal cheese, Aeromonas spp. was isolated in raw and pasteurized milk, in the environment and on the handlers? hands. A. caviae was the most frequently identified species, but A. sobria and A. schubertii were also isolated. During the processing of Colonial cheese, the species A. hydrophila, A. caviae, A. sobria, A. veronii and A. jandaei were isolated in the water, raw milk, after thermal treatment and curd, as well as on the handlers' hands and utensils. The results showed that the genus Aeromonas is disseminated throughout different stages of both cheese processes while the raw milk stands out as the main source of contamination in the industrial and handmade processing

    Long-range versus short-range correlations in the two-neutron transfer reaction Ni 64 (O 18, O 16) Ni 66

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    Recently, various two-neutron transfer studies using the (18O,16O) reaction were performed with a large success. This was achieved because of a combined use of the microscopic quantum description of the reaction mechanism and of the nuclear structure. In the present work we use this methodology to study the two-neutron transfer reaction of the 18O+64Ni system at 84 MeV incident energy, to the ground and first 2+ excited state of the residual 66Ni nucleus. All the experimental data were measured by the large acceptance MAGNEX spectrometer at the Instituto Nazionale di Fisica Nucleare \u2013Laboratori Nazionali del Sud (Italy). We have performed exact finite range cross section calculations using the coupled channel Born approximation (CCBA) and coupled reaction channel (CRC) method for the sequential and direct two-neutron transfers, respectively. Moreover, this is the first time that the formalism of the microscopic interaction boson model (IBM-2) was applied to a two-neutron transfer reaction. From our results we conclude that for two-neutron transfer to the ground state of 66Ni, the direct transfer is the dominant reaction mechanism, whereas for the transfer to the first excited state of 66Ni, the sequential process dominates. A competition between long-range and short-range correlations is discussed, in particular, how the use of two different models (Shell model and IBM's) help to disentangle long- and short-range correlations

    Outbreak Of NDM-1-producing Klebsiella Pneumoniae In A Neonatal Unit In Colombia

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    Six multiresistant, NDM-1-producing Klebsiella pneumoniae strains were recovered from an outbreak that affected six neonatal patients in a Colombian hospital. Molecular analysis showed that all of the isolates harbored the blaNDM-1, qnrA, and intI1 genes and were clonally related. Multilocus sequence typing showed that the isolates belonged to a new sequence type (ST1043) that was different from the sequence types that had previously been reported. This is the first report of NDM-1-producing isolates in South America

    Modeling dose-response relationships of the effects of fesoterodine in patients with overactive bladder

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    <p>Abstract</p> <p>Background</p> <p>Fesoterodine is an antimuscarinic for the treatment of overactive bladder, a syndrome of urgency, with or without urgency urinary incontinence (UUI), usually with increased daytime frequency and nocturia. Our objective was to develop predictive models to describe the dose response of fesoterodine.</p> <p>Methods</p> <p>Data from subjects enrolled in double-blind, placebo-controlled phase II and III trials were used for developing longitudinal dose-response models.</p> <p>Results</p> <p>The models predicted that clinically significant and near-maximum treatment effects would be seen within 3 to 4 weeks after treatment initiation. For a typical patient with 11 micturitions per 24 hours at baseline, predicted change was -1.2, -1.7, and -2.2 micturitions for placebo and fesoterodine 4 mg and 8 mg, respectively. For a typical patient with 2 UUI episodes per 24 hours at baseline, predicted change was -1.05, -1.26, and -1.43 UUI episodes for placebo and fesoterodine 4 mg and 8 mg, respectively. Increase in mean voided volume was estimated at 9.7 mL for placebo, with an additional 14.2 mL and 28.4 mL for fesoterodine 4 mg and 8 mg, respectively.</p> <p>Conclusions</p> <p>A consistent dose response for fesoterodine was demonstrated for bladder diary endpoints in subjects with overactive bladder, a result that supports the greater efficacy seen with fesoterodine 8 mg in post hoc analyses of clinical trial data. The dose-response models can be used to predict outcomes for doses not studied or for patient subgroups underrepresented in clinical trials.</p> <p>Trial Registration</p> <p>The phase III trials used in this analysis have been registered at ClinicalTrials.gov (NCT00220363 and NCT00138723).</p
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