Existence of global strong solutions to a beam-fluid interaction system

We study an unsteady non linear fluid-structure interaction problem which is a simplified model to describe blood flow through viscoleastic arteries. We consider a Newtonian incompressible two-dimensional flow described by the Navier-Stokes equations set in an unknown domain depending on the displacement of a structure, which itself satisfies a linear viscoelastic beam equation. The fluid and the structure are fully coupled via interface conditions prescribing the continuity of the velocities at the fluid-structure interface and the action-reaction principle. We prove that strong solutions to this problem are global-in-time. We obtain in particular that contact between the viscoleastic wall and the bottom of the fluid cavity does not occur in finite time. To our knowledge, this is the first occurrence of a no-contact result, but also of existence of strong solutions globally in time, in the frame of interactions between a viscous fluid and a deformable structure

Far-infrared imaging antenna arrays

A far-infrared imaging antenna array has been demonstrated for the first time. The array is a line of evaporated silver bow-tie antennas on a fused-quartz substrate with bismuth-microbolometer detectors. The measured optical transfer function shows that the system is diffraction limited. This imaging array should find direct application in fusion plasma diagnostics. If the microbolometers can be replaced by more sensitive diode detectors, the array should also find application in radiometry and radar

Calpain-Catalyzed Proteolysis of Human dUTPase Specifically Removes the Nuclear Localization Signal Peptide

Calpain proteases drive intracellular signal transduction via specific proteolysis of multiple substrates upon Ca(2+)-induced activation. Recently, dUTPase, an enzyme essential to maintain genomic integrity, was identified as a physiological calpain substrate in Drosophila cells. Here we investigate the potential structural/functional significance of calpain-activated proteolysis of human dUTPase.Limited proteolysis of human dUTPase by mammalian m-calpain was investigated in the presence and absence of cognate ligands of either calpain or dUTPase. Significant proteolysis was observed only in the presence of Ca(II) ions, inducing calpain action. The presence or absence of the dUTP-analogue α,β-imido-dUTP did not show any effect on Ca(2+)-calpain-induced cleavage of human dUTPase. The catalytic rate constant of dUTPase was unaffected by calpain cleavage. Gel electrophoretic analysis showed that Ca(2+)-calpain-induced cleavage of human dUTPase resulted in several distinctly observable dUTPase fragments. Mass spectrometric identification of the calpain-cleaved fragments identified three calpain cleavage sites (between residues (4)SE(5); (7)TP(8); and (31)LS(32)). The cleavage between the (31)LS(32) peptide bond specifically removes the flexible N-terminal nuclear localization signal, indispensable for cognate localization.Results argue for a mechanism where Ca(2+)-calpain may regulate nuclear availability and degradation of dUTPase

Model for evaluation of the maneuvering object's trajectory using Kalman filters

A new approach for construction of an object maneuvering model for evaluation of movement trajectory using Kalman filter is proposed. The approach proposed is based on application of the object's dynamic equations. Such approach is better for obtaining adequate models of object maneuvering in comparison with the known ones. The state equations of Kahnan filter are derived for describing the movement of a ship maneuvering by the heading

Existence of a weak solution to a nonlinear fluid-structure interaction problem with heat exchange

In this paper, we study a nonlinear interaction problem between a thermoelastic shell and a heat-conducting fluid. The shell is governed by linear thermoelasticity equations and encompasses a time-dependent domain which is filled with a fluid governed by the full Navier-Stokes-Fourier system. The fluid and the shell are fully coupled, giving rise to a novel nonlinear moving boundary fluid-structure interaction problem involving heat exchange. The existence of a weak solution is obtained by combining three approximation techniques–decoupling, penalization and domain extension. In particular, the penalization and the domain extension allow us to use the methods already developed for compressible fluids on moving domains. In such a way, the proof is more elegant and the analysis is drastically simplified. Let us stress that this is the first time the heat exchange in the context of fluid-structure interaction problems is considered

Imaging Antenna Arrays

A far-infrared imaging antenna array has been demonstrated for the first time. The array is a line of evaporated silver bow-tie antennas on a fused-quartz substrate with bismuth-micro-bolometer detectors. The measured optical transfer function shows that the system is diffraction-limited. This imaging array should find direct application in fusion plasma diagnostics. If the microbolometers can be replaced by more sensitive diode detectors, the array should also find application in radiometry and radar