668 research outputs found
Kinetics of exciton photoluminescence in type-II semiconductor superlattices
The exciton decay rate at a rough interface in type-II semiconductor
superlattices is investigated. It is shown that the possibility of
recombination of indirect excitons at a plane interface essentially affects
kinetics of the exciton photoluminescence at a rough interface. This happens
because of strong correlation between the exciton recombination at the plane
interface and at the roughness. Expressions that relate the parameters of the
luminescence kinetics with statistical characteristics of the rough interface
are obtained. The mean height and length of roughnesses in GaAs/AlAs
superlattices are estimated from the experimental data.Comment: 3 PostScript figure
Irreversible and reversible modes of operation of deterministic ratchets
We discuss a problem of optimization of the energetic efficiency of a simple
rocked ratchet. We concentrate on a low-temperature case in which the
particle's motion in a ratchet potential is deterministic. We show that the
energetic efficiency of a ratchet working adiabatically is bounded from above
by a value depending on the form of ratchet potential. The ratchets with
strongly asymmetric potentials can achieve ideal efficiency of unity without
approaching reversibility. On the other hand we show that for any form of the
ratchet potential a set of time-protocols of the outer force exist under which
the operation is reversible and the ideal value of efficiency is also achieved.
The mode of operation of the ratchet is still quasistatic but not adiabatic.
The high values of efficiency can be preserved even under elevated
temperatures
K-string tensions at finite temperature and integrable models
It has recently been pointed out that simple scaling properties of Polyakov
correlation functions of gauge systems in the confining phase suggest that the
ratios of k-string tensions in the low temperature region is constant up to
terms of order T^3. Here we argue that, at least in a three-dimensional Z_4
gauge model, the above ratios are constant in the whole confining phase. This
result is obtained by combining numerical experiments with known exact results
on the mass spectrum of an integrable two-dimensional spin model describing the
infrared behaviour of the gauge system near the deconfining transition.Comment: 22 pages, 7 figures, 1 tabl
KK Parity in Warped Extra Dimension
We construct models with a Kaluza-Klein (KK) parity in a five- dimensional
warped geometry, in an attempt to address the little hierarchy problem present
in setups with bulk Standard Model fields. The lightest KK particle (LKP) is
stable and can play the role of dark matter. We consider the possibilities of
gluing two identical slices of 5D AdS in either the UV (IR-UV-IR model) or the
IR region (UV-IR-UV model) and discuss the model-building issues as well as
phenomenological properties in both cases. In particular, we find that the
UV-IR-UV model is not gravitationally stable and that additional mechanisms
might be required in the IR-UV-IR model in order to address flavor issues.
Collider signals of the warped KK parity are different from either the
conventional warped extra dimension without KK parity, in which the new
particles are not necessarily pair-produced, or the KK parity in flat universal
extra dimensions, where each KK level is nearly degenerate in mass. Dark matter
and collider properties of a TeV mass KK Z gauge boson as the LKP are
discussed.Comment: 35 pages, 11 figure
Influence of mechanical and geometrical properties of embedded long-gauge strain sensors on the accuracy of strain measurement
In many civil and geotechnical applications it is of interest to monitor the strain deep inside the structure; consequently, it is necessary to embed the sensors into the structure's material. Construction and geotechnical materials, such as concrete and soil, can be affected by local defects, e.g. cracks, air pockets and inclusions. To monitor these materials at a structural level it is necessary to use long-gauge sensors. As the sensor has to be embedded in the host material, its presence causes perturbation of the strain field and influences the accuracy of the strain measurement. The aim of this research was to identify the critical parameters that influence the accuracy of the strain measurement, to study how these parameters affect the accuracy, and to give recommendations for sensor users. The study was based on finite element analysis and all involved materials were assumed to have the MöhrCoulomb elastic, perfectly plastic behavior. A suitability of the numerical model for the analysis was verified using the experimental results of two cases reported in the literature and one on-site application. The study revealed that the most important parameters that influence the accuracy of the strain measurement are the goodness of interaction (strain transfer) between the host material and the anchor pieces of the sensor, the ratio between equivalent Young's modulus of the sensor and the Young's modulus of the host material, the radius of the anchor piece and the gauge length. The numerical model and parametric study are presented in detail along with practical recommendations. © 2012 IOP Publishing Ltd.The authors would like to thank the Spanish Ministry of Education, with support received under the National Program for Mobility of Researchers (O.M. EDU/1456/2010, ref. PR2010-0293) which enabled the joint work that made this study possible. The Streicker Bridge project was realized with help of Turner Construction Co., HNTB, AG Construction Corp., Vollers Excavating & Constr., SMARTEC SA, Micron Optics, Princeton Facilities, and staff and students of CEE department of Princeton University.Calderón GarcÃa, PA.; Glisic, B. (2012). Influence of mechanical and geometrical properties of embedded long-gauge strain sensors on the accuracy of strain measurement. Measurement Science and Technology. (23):1-15. https://doi.org/10.1088/0957-0233/23/6/065604S11523GliÅ¡ić, B., & Inaudi, D. (2007). Fibre Optic Methods for Structural Health Monitoring. doi:10.1002/9780470517819Ansari, F. (2007). Practical Implementation of Optical Fiber Sensors in Civil Structural Health Monitoring. Journal of Intelligent Material Systems and Structures, 18(8), 879-889. doi:10.1177/1045389x06075760Li, H.-N., Zhou, G.-D., Ren, L., & Li, D.-S. (2009). Strain Transfer Coefficient Analyses for Embedded Fiber Bragg Grating Sensors in Different Host Materials. Journal of Engineering Mechanics, 135(12), 1343-1353. doi:10.1061/(asce)0733-9399(2009)135:12(1343)Torres, B., Payá-Zaforteza, I., Calderón, P. A., & Adam, J. M. (2011). Analysis of the strain transfer in a new FBG sensor for Structural Health Monitoring. Engineering Structures, 33(2), 539-548. doi:10.1016/j.engstruct.2010.11.012Kesavan, K., Ravisankar, K., Parivallal, S., Sreeshylam, P., & Sridhar, S. (2010). Experimental studies on fiber optic sensors embedded in concrete. Measurement, 43(2), 157-163. doi:10.1016/j.measurement.2009.08.010Azenha, M., Faria, R., & Ferreira, D. (2009). Identification of early-age concrete temperatures and strains: Monitoring and numerical simulation. Cement and Concrete Composites, 31(6), 369-378. doi:10.1016/j.cemconcomp.2009.03.004Glisic, B. (2011). Influence of the gauge length on the accuracy of long-gauge sensors employed in monitoring of prismatic beams. Measurement Science and Technology, 22(3), 035206. doi:10.1088/0957-0233/22/3/035206Leng, J. S., Winter, D., Barnes, R. A., Mays, G. C., & Fernando, G. F. (2006). Structural health monitoring of concrete cylinders using protected fibre optic sensors. Smart Materials and Structures, 15(2), 302-308. doi:10.1088/0964-1726/15/2/009Calderón, P. A., Adam, J. M., Ivorra, S., Pallarés, F. J., & Giménez, E. (2009). Design strength of axially loaded RC columns strengthened by steel caging. Materials & Design, 30(10), 4069-4080. doi:10.1016/j.matdes.2009.05.014Adam, J. M., Ivorra, S., Pallarés, F. J., Giménez, E., & Calderón, P. A. (2009). Axially loaded RC columns strengthened by steel caging. Finite element modelling. Construction and Building Materials, 23(6), 2265-2276. doi:10.1016/j.conbuildmat.2008.11.014Adam, J. M., Ivorra, S., Pallares, F. J., Jiménez, E., & Calderón, P. A. (2008). Column–joint assembly in RC columns strengthened by steel caging. Proceedings of the Institution of Civil Engineers - Structures and Buildings, 161(6), 337-348. doi:10.1680/stbu.2008.161.6.337Adam, J. M., Ivorra, S., Pallares, F. J., Giménez, E., & Calderón, P. A. (2009). Axially loaded RC columns strengthened by steel cages. Proceedings of the Institution of Civil Engineers - Structures and Buildings, 162(3), 199-208. doi:10.1680/stbu.2009.162.3.199Johansson, M., & Gylltoft, K. (2001). Structural behavior of slender circular steel-concrete composite columns under various means of load application. Steel and Composite Structures, 1(4), 393-410. doi:10.12989/scs.2001.1.4.393Johansson, M., & Gylltoft, K. (2002). Mechanical Behavior of Circular Steel–Concrete Composite Stub Columns. Journal of Structural Engineering, 128(8), 1073-1081. doi:10.1061/(asce)0733-9445(2002)128:8(1073
Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay
BACKGROUND: Colorectal cancer (CRC) is the second leading cause of cancer deaths despite the fact that detection of this cancer in early stages results in over 90% survival rate. Currently less than 45% of at-risk individuals in the US are screened regularly, exposing a need for better screening tests. We performed two case-control studies to validate a blood-based test that identifies methylated DNA in plasma from all stages of CRC. METHODOLOGY/PRINCIPAL FINDINGS: Using a PCR assay for analysis of Septin 9 (SEPT9) hypermethylation in DNA extracted from plasma, clinical performance was optimized on 354 samples (252 CRC, 102 controls) and validated in a blinded, independent study of 309 samples (126 CRC, 183 controls). 168 polyps and 411 additional disease controls were also evaluated. Based on the training study SEPT9-based classification detected 120/252 CRCs (48%) and 7/102 controls (7%). In the test study 73/126 CRCs (58%) and 18/183 control samples (10%) were positive for SEPT9 validating the training set results. Inclusion of an additional measurement replicate increased the sensitivity of the assay in the testing set to 72% (90/125 CRCs detected) while maintaining 90% specificity (19/183 for controls). Positive rates for plasmas from the other cancers (11/96) and non-cancerous conditions (41/315) were low. The rate of polyp detection (>1 cm) was approximately 20%. CONCLUSIONS/SIGNIFICANCE: Analysis of SEPT9 DNA methylation in plasma represents a straightforward, minimally invasive method to detect all stages of CRC with potential to satisfy unmet needs for increased compliance in the screening population. Further clinical testing is warranted
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