Etude de l'observance médicamenteuse de la personne agée vivant en foyer-logement

Ce travail de thèse de médecine générale a eu pour but d'étudier l'observance médicamenteuse de 115 personnes âgées vivant en foyer-logement par l'intermédiaire d'entretiens individuels donnant lieu chacun au remplissage d'un questionnaire. Un écart d'observance par mois faisait basculer les patients dans la catégorie " non observant ". L'oubli involontaire s'est avéré la principale cause de mauvaise observance. Le taux d'observance retrouvé en foyer-logement, 74%, était supérieur à celui relevé à domicile, en moyenne 45%, dans d'autres études. Les foyers-logements tendent à procurer des conditions de vie plus favorables que le domicile pour l'observance médicamenteuse.TOULOUSE3-BU Santé-Centrale (315552105) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Alumina-supported vanadium nanoparticles: structural characterization and CO adsorption properties

Alumina-supported vanadium particles were prepared under ultrahigh vacuum (UHV) conditions and characterized with respect to their structural and CO adsorption properties. As supporting oxide, we used a thin, well-ordered alumina film grown on NiAl(110). This allows the application of scanning tunneling microscopy (STM), infrared reflection-absorption spectroscopy (IRAS), and X-ray photoelectron spectroscopy (XPS) without charging effects. Vanadium evaporation under UHV conditions leads to the growth of nanometer-sized particles which strongly interact with the alumina support. At very low vanadium coverages, these particles are partially incorporated into the alumina film and get oxidized through the contact to alumina. Low-temperature CO adsorption in this coverage regime permits the preparation of isolated vanadium carbonyls, of which we have identified mono-, di-, and tricarbonyls of the V(CO)y type. A charge-frequency relationship was set up which allows one to quantify the extent of charge transfer from vanadium to alumina. It turns out that this charge transfer depends on the V nucleation site

Vibrational spectra of alumina- and silica-supported vanadia revisited: An experimental and theoretical model catalyst study

Oxide-supported vanadia particles were prepared via evaporation of vanadium metal in an oxygen ambient. As support oxides, we have employed thin, well-ordered alumina and silica films grown on top of NiAl(110) and Mo(112) surfaces. According to our analysis, the vanadia particles exhibit very similar morphology on both supports but differ in the extent of particle–support interactions. It is shown that these differences in the vanadia–support interface region strongly affect the CO adsorption behavior of the particles. The measured vibrational spectra of the model systems are interpreted on the basis of DFT calculations for model compounds and surface models for both the vanadia/silica and the vanadia/alumina system. The combined information is then compared with Raman spectra of real catalytic materials such as vanadia supported over -Al2O3 and mesoporous SiO2 (MCM-41) taken at different laser wavelengths. A consistent interpretation is developed, which shows that the accepted interpretation of vibrational spectra from vanadia catalysts must be revised