Berezinskii-Kosterlitz-Thouless transitions in an easy-plane ferromagnetic superfluid

A two-dimensional (2D) spin-1 Bose gas exhibits two Berezenskii-Kosterlitz-Thouless (BKT) transitions in the easy-plane ferromagnetic phase. The higher temperature transition is associated with superfluidity of the mass current determined predominantly by a single spin component. The lower temperature transition is associated with superfluidity of the axial spin current, quasi-long range order of the transverse spin density and binding of polar-core spin vortices (PCVs). Above the spin BKT temperature, the component circulations that make up each PCV spatially separate, suggesting possible deconfinement analogous to quark deconfinement in high energy physics. Intercomponent interactions give rise to superfluid drag between the spin components, which we calculate analytically at zero temperature. We present the mass/spin superfluid phase diagram as a function of quadratic Zeeman energy $q$. At $q=0$ the system is in an isotropic spin phase with $\mathrm{SO}(3)$ symmetry. Here the fluid response exhibits a system size dependence, suggesting the absence of a BKT transition. Despite this, for finite systems the decay of spin correlations changes from exponential to algebraic as the temperature is decreased.Comment: 4 pages + refs, 3 figures. Interpretation of Fig. 3 results has changed since v

Intramolecular and Lattice Melting in n-Alkane Monolayers: An Analog of Melting in Lipid Bilayers

URL:http://link.aps.org/doi/10.1103/PhysRevLett.83.2362 DOI:10.1103/PhysRevLett.83.2362Molecular dynamics (MD) simulations and neutron diffraction experiments have been performed on n-dotriacontane ( n-C32D66) monolayers adsorbed on a graphite basal- plane surface. The diffraction experiments show little change in the crystalline monolayer structure up to a temperature of ~350K above which a large thermal expansion and decrease in coherence length occurs. The MD simulations provide evidence that this behavior is due to a phase transition in the monolayer in which intramolecular and translational order are lost simultaneously. This melting transition is qualitatively similar to the gel-to-fluid transition found in bilayer lipid membranes.Acknowledgment is made to the U.S. National Science Foundation under Grants No. DMR-9314235 and No. DMR-9802476, the Missouri University Research Reactor, and to the donors of The Petroleum Research Fund, administered by the ACS, for partial support of this research. We thank L. Criswell for assistance with the figures

Molecular imaging of inflammation and intraplaque vasa vasorum: A step forward to identification of vulnerable plaques?

Current developments in cardiovascular biology and imaging enable the noninvasive molecular evaluation of atherosclerotic vascular disease. Intraplaque neovascularization sprouting from the adventitial vasa vasorum has been identified as an independent predictor of intraplaque hemorrhage and plaque rupture. These intraplaque vasa vasorum result from angiogenesis, most likely under influence of hypoxic and inflammatory stimuli. Several molecular imaging techniques are currently available. Most experience has been obtained with molecular imaging using positron emission tomography and single photon emission computed tomography. Recently, the development of targeted contrast agents has allowed molecular imaging with magnetic resonance imaging, ultrasound and computed tomography. The present review discusses the use of these molecular imaging techniques to identify inflammation and intraplaque vasa vasorum to identify vulnerable atherosclerotic plaques at risk of rupture and thrombosis. The available literature on molecular imaging techniques and molecular targets associated with inflammation and angiogenesis is discussed, and the clinical applications of molecular cardiovascular imaging and the use of molecular techniques for local drug delivery are addressed

Combined In Silico and In Vitro Approach Predicts Low Wall Shear Stress Regions in a Hemofilter that Correlate with Thrombus Formation In Vivo

A major challenge in developing blood-contacting medical devices is mitigating thrombogenicity of an intravascular device. Thrombi may interfere with device function or embolize from the device to occlude distant vascular beds with catastrophic consequences. Chemical interactions between plasma proteins and bioengineered surface occur at the nanometer scale; however, continuum models of blood predict local shear stresses that lead to platelet activation or aggregation and thrombosis. Here, an iterative approach to blood flow path design incorporating in silico, in vitro, and in vivo experiments predicted the occurrence and location of thrombi in an implantable hemofilter. Low wall shear stress (WSS) regions identified by computational fluid dynamics (CFD) predicted clot formation in vivo. Revised designs based on CFD demonstrated superior performance, illustrating the importance of a multipronged approach for a successful design process