17,483 research outputs found
A HOLISTIC APPROACH TO SUSTAINABILITY BASED ON PLURALISTIC STEWARDSHIP
Environmental Economics and Policy,
CONJOINT ANALYSIS OF GROUNDWATER PROTECTION PROGRAMS
Three conjoint models-a traditional ratings model, a ratings difference specification, and a binary response model-were used to value groundwater protection program alternatives. The last, which is virtually identical to a dichotomous choice contingent valuation specification, produced the smallest value estimates. This suggests that the conjoint model is very sensitive to model specifications and that traditional conjoint models may overestimate economic value because many respondents are not in the market for the commodity being valued.Resource /Energy Economics and Policy,
Improving Performance of Iterative Methods by Lossy Checkponting
Iterative methods are commonly used approaches to solve large, sparse linear
systems, which are fundamental operations for many modern scientific
simulations. When the large-scale iterative methods are running with a large
number of ranks in parallel, they have to checkpoint the dynamic variables
periodically in case of unavoidable fail-stop errors, requiring fast I/O
systems and large storage space. To this end, significantly reducing the
checkpointing overhead is critical to improving the overall performance of
iterative methods. Our contribution is fourfold. (1) We propose a novel lossy
checkpointing scheme that can significantly improve the checkpointing
performance of iterative methods by leveraging lossy compressors. (2) We
formulate a lossy checkpointing performance model and derive theoretically an
upper bound for the extra number of iterations caused by the distortion of data
in lossy checkpoints, in order to guarantee the performance improvement under
the lossy checkpointing scheme. (3) We analyze the impact of lossy
checkpointing (i.e., extra number of iterations caused by lossy checkpointing
files) for multiple types of iterative methods. (4)We evaluate the lossy
checkpointing scheme with optimal checkpointing intervals on a high-performance
computing environment with 2,048 cores, using a well-known scientific
computation package PETSc and a state-of-the-art checkpoint/restart toolkit.
Experiments show that our optimized lossy checkpointing scheme can
significantly reduce the fault tolerance overhead for iterative methods by
23%~70% compared with traditional checkpointing and 20%~58% compared with
lossless-compressed checkpointing, in the presence of system failures.Comment: 14 pages, 10 figures, HPDC'1
An algebraic interpretation of the Wheeler-DeWitt equation
We make a direct connection between the construction of three dimensional
topological state sums from tensor categories and three dimensional quantum
gravity by noting that the discrete version of the Wheeler-DeWitt equation is
exactly the pentagon for the associator of the tensor category, the
Biedenharn-Elliott identity. A crucial role is played by an asymptotic formula
relating 6j-symbols to rotation matrices given by Edmonds.Comment: 10 pages, amstex, uses epsf.tex. New version has improved
presentatio
Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from northwestern Uganda following melarsoprol withdrawal
Human African trypanosomiasis (HAT) manifests as a chronic infection caused by <i>Trypanosoma brucei gambiense</i>, or as a more acute form due to <i>T. b. rhodesiense</i>. Both manifestations occur in Uganda and melarsoprol use against the former was jeopardised in the 1990s as reports of reduced efficacy increased to the point where it was dismissed as first-line treatment at some treatment centers. Previous work to elucidate possible mechanisms leading to melarsoprol resistance pointed to a P2 type adenosine transporter known to mediate melarsoprol uptake and previously shown to be mutated in significant numbers of patients not responding to the drug. Our present findings indicate that there is a low prevalence of mutants in foci where melarsoprol relapses are infrequent. In addition we observe that at the Omugo focus where the drug was withdrawn as first line over 6 years ago, the mutant alleles have disappeared, suggesting that drug pressure is responsible for fuelling their spread. Thus constant monitoring for mutants could play a key role in cost-effective HAT management by identifying which foci can still use the less logistically demanding melarsoprol as opposed to the alternative drug eflornithine. What is required now is a simple method for identifying such mutants at the point of care, enabling practitioners to make informed prescriptions at first diagnosis
Development of the Motivational Interviewing Supervision and Training Scale
The movement to use empirically supported treatments has increased the need for researchers and supervisors to evaluate therapists’ adherence to and the quality with which they implement those interventions. Few empirically supported approaches exist for providing these types of evaluations. This is also true for motivational interviewing, an empirically supported intervention important in the addictions field. This study describes the development and psychometric evaluation of the Motivational Interviewing Supervision and Training Scale (MISTS), a measure intended for use in training and supervising therapists implementing motivational interviewing. Satisfactory interrater reliability was found (generalizability coefficient p2 = .79), and evidence was found supporting the convergent and discriminant validity of the MISTS. Recommendations for refinement of the measure and future research are discussed
How to measure the spreading width for decay of superdeformed nuclei
A new expression for the branching ratio for the decay via the E1 process in
the normal-deformed band of superdeformed nuclei is given within a simple
two-level model. Using this expression, the spreading or tunneling width
Gamma^downarrow for superdeformed decay can be expressed entirely in terms of
experimentally known quantities. We show how to determine the tunneling matrix
element V from the measured value of Gamma^downarrow and a statistical model of
the energy levels. The accuracy of the two-level approximation is verified by
considering the effects of the other normal-deformed states.Comment: 4 pages, 4 figure
Three and Four Harmonically Trapped Particles in an Effective Field Theory Framework
We study systems of few two-component fermions interacting via short-range
interactions within a harmonic-oscillator trap. The dominant interactions,
which are two-body, are organized according to the number of derivatives and
defined in a two-body truncated model space made from a bound-state basis.
Leading-order (LO) interactions are solved for exactly using the formalism of
the No-Core Shell Model, whereas corrections are treated as many-body
perturbations. We show explicitly that next-to-LO and next-to-next-to-LO
interactions improve convergence as the model space increases. We present
results at unitarity for three- and four-fermion systems, which show excellent
agreement with the exact solution (for the three-body problem) and results
obtained by others methods (in the four-body case). We also present results for
finite scattering lengths and non-zero range of the interaction, including (at
positive scattering length) observation of a change in the structure of the
three-body ground state and extraction of the atom-dimer scattering length.Comment: 18 pages, 10 figure
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(Non)Parallel Evolution
Parallel evolution across replicate populations has provided evolutionary biologists with iconic examples of adaptation. When multiple populations colonize seemingly similar habitats, they may evolve similar genes, traits, or functions. Yet, replicated evolution in nature or in the laboratory often yields inconsistent outcomes: Some replicate populations evolve along highly similar trajectories, whereas other replicate populations evolve to different extents or in distinct directions. To understand these heterogeneous outcomes, biologists are increasingly treating parallel evolution not as a binary phenomenon but rather as a quantitative continuum ranging from parallel to nonparallel. By measuring replicate populations’ positions along this (non)parallel continuum, we can test hypotheses about evolutionary and ecological factors that influence the extent of repeatable evolution. We review evidence regarding the manifestation of (non)parallel evolution in the laboratory, in natural populations, and in applied contexts such as cancer. We enumerate the many genetic, ecological, and evolutionary processes that contribute to variation in the extent of parallel evolution
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