895 research outputs found
Racial Profiling and the War on Terror: Changing Trends and Perspectives
Minorities in the United States have often been treated unfairly by law enforcement agencies. Prior to the September 11, 2001, terrorist attack on the United States, Blacks were the main victims of racial profiling. Since the terrorist attack, however, Arabs and Muslims are becoming the primary targets for profiling by law enforcement agencies. There are some remarkable similarities between the profiling of Blacks and the profiling of Arabs and Muslims. In both cases, the fundamental problems with racial profiling are that it violates the civil liberties of innocent people and denies minorities the equal protection of the law. The War on Terror has redefined racial profiling. It has not only led to a shift in the target population, but it has also changed the ways in which racial profiling is conducted
Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and Haemophilus influenzae type b (Hib). Methods: We conducted a retrospective analysis of SCA patients admitted to the Medical Research Council Unit, The Gambia during a five-year period when there was high coverage of Hib and Pneumococcal conjugate vaccination. We evaluated 161 admissions of 126 patients between April 2010 and April 2015. Results: Pathogenic bacteria were identified in blood cultures from 11 of the 131 admissions that had cultures taken (8.4%, 95% CI 4.5-14.1%). The most frequent isolate was Salmonella Typhimurium (6/11; 54.5%), followed by Staphylococcus aureus (2/11; 18.2%) and other enteric Gram-negative pathogens (2/11; 18.2%) and there was one case of H. influenzae non-type b bacteraemia (1/11; 9.1%). There were no episodes of bacteraemia caused by S. pneumoniae or Hib. Conclusions: The low prevalence of S. pneumoniae and Hib, and the predominance of non-typhoidal Salmonella as a cause of bacteraemia suggest the need to reconsider optimal antimicrobial prophylaxis and the empirical treatment regimens for patients with SCA
Cryopreservation of mature embryos of coconut (Cocos nucifera L.) and subsequent regeneration of plantlets
Cryopreservation of immature embryos of coconut (Cocos nucifera L.)
Réponse d'embryons immatures de cocotiers (7 à 8 mois après la pollinisation) à la congélation par azote liquide (-196¼C) : survie et germinatio
Use of zygotic embryo culture to collect germplasm of coconut (Cocos nucifera L.)
The in vitro culture of zygotic embryos solves the problems encountered in transporting and storing coconut seeds (Cocos nucifera L.). especially when obtained under field collecting conditions. Embryo sampling and short-term storage methods have been developed. Direct inoculation into culture on media, enabling embryo growth under axenic conditions. has been successfully carried out under field collecting conditions. An alternative method holds embryos in endosperm cores in a salt solution for brief periods before excision and inoculation into culture in a laboratory. The techniques and equipment used are described in this paper, as well as the subsequent development of the ernbryos and the transfer of plants to natural growing conditions
A four-month gatifloxacin-containing regimen for treating tuberculosis.
BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin-sensitive pulmonary tuberculosis. METHODS: We conducted a noninferiority, randomized, open-label, controlled trial involving patients 18 to 65 years of age with smear-positive, rifampin-sensitive, newly diagnosed pulmonary tuberculosis in five sub-Saharan African countries. A standard 6-month regimen that included ethambutol during the 2-month intensive phase was compared with a 4-month regimen in which gatifloxacin (400 mg per day) was substituted for ethambutol during the intensive phase and was continued, along with rifampin and isoniazid, during the continuation phase. The primary efficacy end point was an unfavorable outcome (treatment failure, recurrence, or death or study dropout during treatment) measured 24 months after the end of treatment, with a noninferiority margin of 6 percentage points, adjusted for country. RESULTS: A total of 1836 patients were assigned to the 4-month regimen (experimental group) or the standard regimen (control group). Baseline characteristics were well balanced between the groups. At 24 months after the end of treatment, the adjusted difference in the risk of an unfavorable outcome (experimental group [21.0%] minus control group [17.2%]) in the modified intention-to-treat population (1356 patients) was 3.5 percentage points (95% confidence interval, -0.7 to 7.7). There was heterogeneity across countries (P=0.02 for interaction, with differences in the rate of an unfavorable outcome ranging from -5.4 percentage points in Guinea to 12.3 percentage points in Senegal) and in baseline cavitary status (P=0.04 for interaction) and body-mass index (P=0.10 for interaction). The standard regimen, as compared with the 4-month regimen, was associated with a higher dropout rate during treatment (5.0% vs. 2.7%) and more treatment failures (2.4% vs. 1.7%) but fewer recurrences (7.1% vs. 14.6%). There was no evidence of increased risks of prolongation of the QT interval or dysglycemia with the 4-month regimen. CONCLUSIONS: Noninferiority of the 4-month regimen to the standard regimen with respect to the primary efficacy end point was not shown. (Funded by the Special Program for Research and Training in Tropical Diseases and others; ClinicalTrials.gov number, NCT00216385.)
Culture in vitro d'embryons zygotiques de cocotier (Cocos nucifera L.). Méthode révisée et simplifiée d'obtention de plants de cocotiers transférables au champ
Des améliorations ont été apportées à la technique de culture in vitro des embryons zygotiques de cocotier. La suppression de l'haustorium sur des embryons ayant développé une gemmule de 2 à 4 cm a entraîné une meilleure survie des plants après leur passage sur sable. L'augmentation de la concentration en saccharose dans le milieu a permis d'accélérer le développement des embryons. Dans ce cas, le système radiculaire formé sans adjonction d'auxines rhizogènes a été satisfaisant. On a obtenu ainsi, en 5 mois, des plantules vigoureuses ayant un développement harmonieux après leur passage en conditions naturelle
Species occurrence of cetaceans in Guinea, including humpback whales with southern hemisphere seasonality
An initial inventory of the dolphins and whales occurring in Guinea's coastal waters is documented primarily from specimens and photographic evidence obtained from strandings and by-catches. Seven species are fully validated, four odontocetes, Tursiops truncatus, Sousa teuszii, Stenella frontalis, Kogia breviceps and three balaenopterid whales: Balaenoptera brydei, Balaenoptera acutorostrata and Megaptera novaeangliae. Another three reported species (Globicephala macrorhynchus, Steno bredanensis and Delphinus delphis) are insufficiently supported but thought to be valid. Small cetaceans landed as by-catch and a stranded whale were used for human consumption, but no evidence of substantial takes, directed or by-catch, was found. However, concern is raised about even minimal takes of the vulnerable Atlantic humpback dolphin. The seasonal presence of three confirmed humpback whales, two strandings (July and September) and a sighting (October), is synchronous with the species' southern hemisphere wintering/breeding season in low latitudes. We hypothesize that these whales may comprise the north-westernmost range of the population that breeds/overwinters in coastal waters of the Bight of Benin, northern Gulf of Guinea
The cetaceans of Guinea, a first check-list of documented species. Scientific Committee document SC/58/O15, International Whaling Commission, May-June 2006, St. Kitts
A CMS workshop on West African Cetacea (Conakry, May 2000), called for i.a. ‘carrying out .. inventory of cetacean species; collection, treatment and compilation of data for each state.’ The present paper is a preliminary faunal checklist of cetaceans occurring in Guinea’s EEZ. Information was gleaned from strandings, bycatches, scientific and opportunistic sightings and a literature review. Ten species are included for which supporting voucher material and data were available for examination. These are, three baleen whales: Balaenoptera brydei, Balaenoptera acutorostrata and Megaptera novaeangliae; and seven species of odontocetes: Kogia breviceps, Tursiops truncatus, Sousa teuszii, Stenella frontalis, Delphinus delphis, Steno bredanensis and Globicephala macrorhynchus. Another two species, Physeter macrocephalus and Stenella attenuate were sighted off Guinea but no photographic evidence was obtained. The current account is thought to reflect an incomplete picture of Guinea’s cetacean biodiversity. Future surveys are expected to update and investigate spatial and temporal distribution patterns for each species along Guinea’s coast. A few bycatches landed by artisanal fishers were utilised locally, but there are no signs of any substantial captures. Nonetheless, monitoring should be continued. The set-up of a national reference collection and database is recommended. The population identities of the encountered Atlantic humpback dolphin, minke whale and humpback whale are of particular interest
- …
