Synthesis and antibacterial studies of azodispersed dyes derived from 2-(thiazol-2-yl)phthalazine-1,4-diones Synthesis and antimicrobial of new anthraquinone derivatives incorporating pyrazole moiety

Abstract A dibenzobarrelene derivative was used as key intermediate for the synthesis of 2-(4-(methyl/phenylthiaz-ol-2-yl)-2,3,4a,5,10,10a-hexahydro-5,10-benzenobenzo[g]phthalazine-1,4-diones. These compounds were coupled with the appropriate diazonium chlorides to give the corresponding 5-(arylazo)thiazole derivatives. The synthesized dyes were applied to polyester as disperse dyes, and their antibacterial, color measurement, and fastness properties were evaluated. Abstract Treatment of 2-cyano-N-(9,10-dioxo-9,10-dihydro-anthracen-2-yl)-acetamid

Improving healthspan via changes in gut microbiota and fermentation

Dietary resistant starch impact on intestinal microbiome and improving healthspan is the topic of this review. In the elderly population, dietary fiber intake is lower than recommended. Dietary resistant starch as a source of fiber produces a profound change in gut microbiota and fermentation in animal models of aging. Dietary resistant starch has the potential for improving healthspan in the elderly through multiple mechanisms as follows: (1) enhancing gut microbiota profile and production of short-chain fatty acids, (2) improving gut barrier function, (3) increasing gut peptides that are important in glucose homeostasis and lipid metabolism, and (4) mimicking many of the effects of caloric restriction including upregulation of genes involved in xenobiotic metabolism