12 research outputs found

    Comments on the Refractive Index of Tin Sulphide Nano-crystalline Thin Films

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    The refractive indices of nano-crystalline thin films of Tin (IV) Sulphide (SnS) were investigated here. The experimental data conformed well with the single oscillator model for refractive indices. Based on the this, we explain the increasing trend of refractive index to the improvement in crystal ordering with increasing grain size.Comment: Nine figure

    Examining Brain Structure after Pediatric Mild Traumatic Brain Injury

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    Mild traumatic brain injuries (mTBIs) affect millions of children annually and present a huge burden to the public health care system. mTBIs often lead to emotional, cognitive, and physical difficulties, together known as post concussive symptoms (PCS), which usually resolve within 4 weeks of injury. In up to one third of all mTBI cases, PCS can be longer lasting and are referred to as persistent PCS (PPCS). In the pediatric population, since mTBI occurs when the brain is still developing, it can lead to altered developmental trajectories, and consequently affect children's cognitive functioning, symptomatology, and quality of life. This thesis aimed to use advanced neuroimaging techniques, [i.e., diffusion tensor imaging (DTI), neurite orientation dispersion and density imaging (NODDI), and voxel-based morphometry (VBM)] to study unexamined aspects of brain structure associated with mTBI, PPCS, and neurocognitive outcomes after mTBI. I used DTI and NODDI to examine white matter microstructure after mTBI at different time points after injury in comparison to orthopedic injury (OI) and used VBM to examine cerebellar gray matter volume and its association to neurocognitive outcomes of mTBI. The results revealed: 1) No post-acute differences in brain structure (white matter microstructure or gray matter) between children with mTBI or OI, 2) Age moderated differential trajectories of white matter change, 3- and 6-months post-injury in symptomatic children with mTBI compared to asymptomatic children with mTBI and an OI comparison group, 3) Higher gray matter volume in the motor regions of the cerebellum 3-months after injury in the mTBI compared to the OI group, 4) Disruptions in the association between reaction time and cerebellar volume in children with mTBI. This novel set of studies provides new knowledge about brain structure following pediatric mTBI and has important implications for improving our understanding of neurobiological correlates of pediatric mTBI

    Role of platelet count in diagnosis of oral potentially malignant disorders and oral squamous cell carcinoma

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    Introduction: Platelets play an important role in the metabolic functions of malignant tissues. Platelet count is the major marker for malignancy and their increase in number can depict stages, severity and metastasis of cancer.  Increase in number of platelet count can be used in early diagnosis of cancer. However, use of some chemotherapeutic agents is associated with low platelet count. Therefore, the platelet to cancer cell ratio varies through the course of the disease and is highly affected by treatment. Aim: To assess correlation between platelet count and progression of malignancy. Materials and method: Platelet counts were retrieved from patients diagnosed oral potentially malignat disorders and oral squamous cell carcinoma based on clinical data. The collected data is analyzed to correlate the platelet count in oral potentially malignat disorders and oral squamous cell carcinoma compared to healthy control patients. Result: Nonsignificant differnce was noted in platelet count in oral potentially malignat disorders and oral squamous cell carcinoma compared to healthy control patients. Conclusion: Thrombocystosis is a poor predicator for malignancy, platelet count alone cannot determine the severity of malignancy, correlation with histopathologic data can better establish the grading of malignancy

    Role of Platelet Count in Diagnosis of Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma

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    Introduction: Platelets play an important role in the metabolic functions of Malignant tissues. Platelet count is the major marker for Malignancy and their increase in number can depict stages, severity and metastasis of cancer.  Increase in number of platelet count can be used in early diagnosis of cancer. However, use of some chemotherapeutic agents is associated with low platelet count. Therefore, the platelet to cancer cell ratio varies through the course of the disease and is highly affected by treatment. Aim: To assess correlation between platelet count and progression of Malignancy. Materials and method: Platelet counts were retrieved from patients diagnosed oral potentially Malignat disorders and oral squamous cell carcinoma based on clinical data. The collected data is analyzed to correlate the platelet count in oral potentially Malignat disorders and oral squamous cell carcinoma compared to healthy control patients. Result: Nonsignificant differnce was noted in platelet count in oral potentially Malignat disorders and oral squamous cell carcinoma compared to healthy control patients. Conclusion: Thrombocystosis is a poor predicator for Malignancy, platelet count alone cannot determine the severity of Malignancy, correlation with histopathologic data can better establish the grading of Malignancy

    Convolvulus plant—A comprehensive review from phytochemical composition to pharmacy

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    Convolvulus genus is a representative of the family of Convolvulaceae. Convolvulus plants are broadly distributed all over the world and has been used for many centuries as herbal medicine. Convolvulus genus contains various phytochemicals such as flavonoids, alkaloids, carbohydrates, phenolic compounds, mucilage, unsaturated sterols or terpenes, resin, tannins, lactones, and proteins. This review highlights the phytochemical composition, antimicrobial and antioxidant activities, application as food preservative, traditional medicine use, anticancer activities, and clinical effectiveness in human of Convolvulus plants. All the parts of Convolvulus plants possess therapeutic benefits; preliminary pharmacological data validated their use in traditional medicine. However, further preclinical and clinical experiments are warranted before any application in human health

    Boundary driven unconventional mechanism of macroscopic magnetic field generation in beam-plasma interaction

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    The all pervading magnetic field in nature has aroused great curiosity and spawned many efforts to understand its generation. We propose, simulate, and experimentally demonstrate another mechanism of long-scale magnetic field generation in the context of a laser-plasma interaction. It relies on two realistic features, namely the finite size of the laser generated electron beam and an initial current imbalance. It is shown that magnetic fields of scale lengths comparable to the transverse beam dimension, are generated much before the onset of conventional instabilities associated with the beam-plasma system. This is due to radiative leakage at the boundaries of the finite beam, wherein even a small but finite current imbalance plays the crucial role of a radiative antenna. These features have been absent in simulations and theoretical analyses using the periodic boundary condition
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