85 research outputs found

    Acceptability, reliability, validity and responsiveness of the Turkish version of WOMAC osteoarthritis index

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    SummaryObjectiveTo evaluate the acceptability, reliability, validity and responsiveness of the Turkish version of Western Ontario and McMaster Universities (WOMAC) osteoarthritis (OA) index in physiotherapy outpatient practice in Turkey.MethodData were obtained from 72 patients with OA of the knee. They were asked to answer two disease-specific questionnaires (WOMAC LK 3.1 and Lequesne-Algofunctional Index of Severity for the knee) and one generic instrument (Medical Outcomes study SF-36 Survey-SF-36). Acceptability was assessed in terms of refusal rate, rates of missing responses, and administration time. Reliability was assessed using Cronbach's alpha. Content validity was assessed by examining the floor and ceiling effects, and skew of the distributions. Convergent and divergent validity was assessed by examining the Pearson's correlation coefficients. Responsiveness was determined by examining effect size (ES), standardized response means (SRM) and P values generated using Wilcoxon's test.ResultsThe overall response rate was 100%. Alpha values for all WOMAC subscales exceeded the value of 0.70 at both baseline and follow-up assessments. Frequency distributions of scores were symmetrical. Subscales had negligible floor and ceiling effects. Both pain and physical function subscales were fairly correlated with the subscales measuring similar constructs of SF-36, whereas they were weakly correlated with other dimensions of SF-36. A good correlation was obtained between WOMAC total and Lequesne index. The pain and physical function subscales of WOMAC index were the most responsive subscales.ConclusionThe Turkish WOMAC OA index is acceptable, valid, reliable and responsive for use in Turkish patients with knee OA

    Medya ve güvenlik sektörü gözetimi: sınırlar ve imkânlar

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    Media and security sector oversights: limits and potential

    Accendendo una candela: religione e trasformazione dello spazio urbana a Istanbul

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    Burning a candle: religion and the transformation of the urban space in Istanbu

    Il potere dell'acqua

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    The power of water In this article, the authors evaluate the growing importance of water and the so-called "water wars" especially in light of the 5th World Water Forum organized in Istanbul, Turkey. For Turkey and its surrounding region, water has long been a source for geostrategic power, a maker and breaker of peace, as well as an important socio-economic developmental lever. The authors also concentrate on the ways in which water has recently become an arena for neoliberal economic policies and a way to further weaken public economies

    Cytotoxic sesquiterpene coumarins from the roots of heptaptera cilicica

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    Preliminary 2-day cancer cell screening assays indicated that the dichloromethane extract of the roots of Heptaptera cilicica showed relatively strong cytotoxic activity. Eleven sesquiterpene coumarin ethers with potent and selective cytotoxic activities were isolated from the dichloromethane extract of the roots of H. cilicica. Furthermore, revised spectroscopic data for 14'-acetoxybadrakemone (4) and complete NMR spectroscopic assignments for colladonin (6) and colladin (7) are reported
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