Coronavirus Disease-19 (Covid-19): the Disease That Changed the World

DergiPark: 762686tmsjIn December 2019, several cases of severe pneumonia were identified in Wuhan City, the capital of Hubei province. Upon further investigation, the pathogen causing these symptoms was identified and named as SARS-CoV-2 and the disease was given the name COVID-19 by the World Health Organization. Being able to spread rapidly through respiratory droplets and capable of asymptomatic transmission, COVID-19 became a health concern of a global scale in a matter of months. The most common signs and symptoms of COVID-19 patients at hospital admission are fever, dry cough, and dyspnea. Most people experience the disease with mild symptoms but in more severe cases these can develop into pneumonia and acute respiratory distress syndrome. In this review, we aim to summarize the current information over COVID-19 and its causative agent SARS-CoV-2

Management of a T-Tube Migration Into the Syrinx Cavity: a Case Report

DergiPark: 889380tmsjAims: To present a rare syringomyelia case that necessitated a revision surgery because of a T-tube migration into the syrinx cavity. Case Report: A 53-year-old female patient was presented with progressive pain in the right arm and numbness in the neck. She had undergone decompression and stabilization surgery at the T6-T9 levels four years ago. One year later, she underwent a T-tube placement operation for syringomyelia. She remained relatively stable until the latest admission. A detailed neurological examination revealed no difference compared to her previous neurological condition. Computerized Tomography and Magnetic Resonance Imaging scans demonstrated that the syrinx had expended and the T-tube had migrated into the syrinx cavity. A revision was carried out, the migrated T-tube was removed through fenestration, and a new T-tube was placed. Her condition had significantly improved at follow-up, and the syrinx had markedly regressed. Conclusion: Syringosubarachnoid shunting operations might lead to rare complications such as T-tube migration, which necessitate revision surgery. Nearly complete relief of symptoms can be achieved with successful revision surgery

Retrospective Analysis of Follicular Lymphoma Patients in Trakya University School of Medicine: a Single Center Experience

DergiPark: 889334tmsjAims: To establish a dataset including demographic features, disease characteristics, and survival rate of follicular lymphoma patients in Trakya Universi- ty School of Medicine and contribute to the database of follicular lymphoma in Turkey. Methods: In this retrospective cross-sectional study, we analyzed data constituting of follicular lymphoma patients over 18 years of age followed during the years of 2015-2020 in Trakya University Division of Hematology. Results: Out of 43 patients, 22 (51.2%) were female and 21 (48.8%) were male. The mean age was 56.56 (standard deviation 13.24) years. There were 5 (11.6%) pa- tients with B symptoms, presence of bone marrow involvement was seen in 17 (39.5%) patients, lastly, there were 18 (41.9%) patients with splenomegaly. Twen- ty-one (48.8%) patients received rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate, and prednisone, making it the most common treatment protocol administered in our study. Conclusion: Follicular lymphoma patients usually end up getting diagnosed at an advanced stage of the disease, presenting with incidentally noticed painless lymphadenopathy. Additionally, based on evidence in the literature, a clear gap in the successful diagnosis of follic- ular lymphoma patients can be observed between developed and developing countries. To overcome this hurdle, enhanced cooperation with hematopathology may lead to an increased awareness enabling physicians to make a more accurate diagnosis. Nonetheless, further studies are still needed to fully apprehend the epidemiology of follicular lymphoma patients in Turkey

Case Report of An Incidental Unicentric Castleman Disease

DergiPark: 889347tmsjAims: To emphasize the hardship of diagnosing Castleman disease and present a potential treatment method. Case Report: A sixty-three-year-old male patient was admitted to the outpatient clinic with an attack of acute cholecystitis. The patient’s abdominal computed tomography revealed an incidentally detected lipid dense solid mass (64x53x37 mm) at the level of right renal hilum with 29x13 mm solid components in the middle. The patient was admitted to the urology department and underwent surgery where the mass was totally excised due to suspicion of a malignancy (liposarcoma). Histopathological examination later on resulted with unicentric Castleman disease, hyaline vascular subtype. Conclusion: Since unicentric Castleman disease has an asymptomatic clinical course and is quite rare, it is necessary to rule out many potential possibilities before reaching a proper diagnosis. However, unicentric Castleman disease usually exhibits a good prognosis after the removal of the affected lymph node. Still, Castleman disease should be a candidate considered in the differential diagnosis of patients with incidentally discovered lymphadenopathy. On the whole, for a better understanding of underlying pathophysiology, there still lies a gap to be filled with knowledge acquired through further studies