2 research outputs found
Preliminary Study on The Effect of Medicinal Mushroom Extract and Timolol Maleate on Dexamethasone Induced Ocular Hypertension in Feline's Eye Model
Mushrooms are like mannas and their water heal eye diseases. To
determine if aqueous mushroom extract has an effect on ocular
hypertension, 8 cats with baseline intra ocular pressure (IOP) of 14.94
\ub1 0.153mmHg were used in the first phase of this study. The second
phase consisted of 2 groups, the experimental and the control groups.
The control consisted of 2 cats (4 eyes) while the experimental
consisted of 6 cats (12 eyes). Ocular hypertension was induced in the
experimental group with 0.1% dexamethasone treatment (2 drops q.i.d x
1/12) and IOP measurement was done weekly using the Perkins hand held
Tonometer. The third phase consisted of oculo hypertensive cat eyes
(25.275 \ub1 0.363mmHg), which were further divided into control-1
and experimental group. The control-1 group (4 eyes) was left
untreated, while the experimental group was divided into 2 groups, the
mushroom treated (4 eyes) and timolol treated (4 eyes) for 15 days.
Mushroom extract decreasel IOP below baseline level showing a
significant (p < 0.001) IOP reduction of 5.24% better than the
control group, while timolol was only 0.85% better
Preliminary Study on The Effect of Medicinal Mushroom Extract and Timolol Maleate on Dexamethasone Induced Ocular Hypertension in Feline's Eye Model
Mushrooms are like mannas and their water heal eye diseases. To
determine if aqueous mushroom extract has an effect on ocular
hypertension, 8 cats with baseline intra ocular pressure (IOP) of 14.94
± 0.153mmHg were used in the first phase of this study. The second
phase consisted of 2 groups, the experimental and the control groups.
The control consisted of 2 cats (4 eyes) while the experimental
consisted of 6 cats (12 eyes). Ocular hypertension was induced in the
experimental group with 0.1% dexamethasone treatment (2 drops q.i.d x
1/12) and IOP measurement was done weekly using the Perkins hand held
Tonometer. The third phase consisted of oculo hypertensive cat eyes
(25.275 ± 0.363mmHg), which were further divided into control-1
and experimental group. The control-1 group (4 eyes) was left
untreated, while the experimental group was divided into 2 groups, the
mushroom treated (4 eyes) and timolol treated (4 eyes) for 15 days.
Mushroom extract decreasel IOP below baseline level showing a
significant (p < 0.001) IOP reduction of 5.24% better than the
control group, while timolol was only 0.85% better