Bir devlet hastanesinin ilk yılında gerçekleştirilen 52 olguluk tiroid ince-iğne aspirasyon biyopsilerinin retrospektif tanısal analizi

Nodüler tiroidal hastalık, sıklıkla gözlenir (ultrasonografik değerlendirmelerde ve otopsilerde %25-40) ve klinik pratikte zorluklara yol açmaktadır. Sık görülen ve kadınlarda, iyot eksikliğine, radyasyona maruz kalanlarda ve artan yaşla insidansı yükselen, genellikle benign bir hastalıktır. Biz, bir perifer devlet hastanesinin ilk yılında, tek cerrah tarafından uygulanan, tiroid bezi ince-iğne aspirasyon biyopsisi (TIIAB) tanısal sonuçlarının retrospektif analizini raporlamayı amaçladık. Çalışmada, Ekim 2006 ve Şubat 2008 tarihleri arasında Ankara Gölbaşı Hasvak Devlet Hastanesi, Genel Cerrahi Kliniği'nde gerçekleştirilen 52 TIIAB retrospektif olarak değerlendirildi ve yetersiz, benign, şüpheli ve malign olarak sınıflandırıldı. Olgularımızın büyük çoğunluğu benign karekterdeydi ve benign olanların geneli kolloidal nodüler sitolojiye sahipti. Elli iki olgu arasında yalnızca iki şüpeli olgu saptandı ve postoperatif olarak bir tanesi papiller tiroid karsinoması olarak adlandırılan tiroid malignitesini sergilemişti. Bu çalışma sadece, bir ilçenin tek hastanesinin ilk yılında, hastaneye başvuran hastaların tiroid bezi ince-iğne aspirasyon sitolojilerinin retrospektif analizini göstermek amacıyla yapılmıştır.The disease of nodular thyroid is frequently observed (25- 40% in ultrasonographic evaluations and autopsies) and has difficulties in clinical practice. It is a common and frequently benign disease having incidence which increases with age, and is increased in women, in people with iodine deficiency, and after radiation exposure. We aimed to report the retrospective analysis of diagnostic results of fine-needle aspiration biopsy (FNAB) of thyroid gland is performed from one surgeon in the first year of a peripheral state hospital. In the present study, 52 fine-needle aspiration cytology of the thyroid gland (FNAC-t) is performed at Department of General Surgery, Ankara Golbasi Hasvak State Hospital between the dates of October 2006 and February 2008 evaluated retrospectively and classified as non-diagnostic, benign, indeterminate, and malignant. Agreat majority of our cases had benign character and the generality of the benign ones had colloidal nodular cytology. Only two indeterminate cases were detected among the 52 cases and postoperatively, one of them had been exhibited thyroidal malignity called papillary thyroidal carcinoma. This study was performed to show only a retrospective analysis of FNAC-t about the patients applying to the unique hospital of a county in the interval of the first year of the hospital

A 80-year-old woman with B-cell prolymphocytic leukemia

Prolymhocytic leukemia (PLL) is a rare subtype of lymphocytic leukemias and its cells are immature lymphocytes. It is divided into 2 subgroups: T-PLL and B-PLL according to the lymphocytic origin of the cells. Discriminating B-PLL from other diseases with clinically-similar features is important because of the different treatment approaches and follow-up programs. Hereby, we report a 80-year-old woman presenting with fatigue, leucocytosis and mild anemia. Her peripheral blood smear evaluation revealed 85% prolymphocytes with moderately condensed nuclear chromatin, prominent nucleoli, and a faintly basophilic cytoplasm. Positron emission tomography-computed tomography showed mediastinal lymph nodes with cervical lymph nodes. There was no pathological FDG involvement in the spleen. Bone marrow aspiration smear exhibit atypical wide lymphocytes with prominent nucleoli and abundant agranular cytoplasm. Flow cytometry analysis revealed positive CD5+, CD19+, CD20+, CD22+, CD11c+, CD25+, CD79a+ and CD79b+. Fluorescence in situ hybridization technique analysis reveals no t(11;14). Bone marrow biopsy revealed interstitially distributed atypical cells with wide nucleus and prominent nucleolus