19 research outputs found
Forensic analysis of the Turkey 2023 presidential election
Concerns about the integrity of Turkey's elections have increased with the
recent transition from a parliamentary democracy to an executive presidency
under Recep Tayyip Erdogan. Election forensics tools are used to identify
statistical traces of certain types of electoral fraud, providing important
information about the integrity and validity of democratic elections. Such
analyses of the 2017 and 2018 Turkish elections revealed that malpractices such
as ballot stuffing or voter manipulation may indeed have played a significant
role in determining the election results. Here, we apply election forensic
statistical tests for ballot stuffing and voter manipulation to the results of
the first round of the 2023 presidential election in Turkey. We find that the
2023 elections exhibit similar statistical irregularities to those observed in
the 2018 presidential elections, however the magnitude of these distortions has
decreased. We estimate that 2.4% (SD 1.9%) of electoral units may have been
affected by ballot-stuffing practices in favour of Erdogan, compared to 8.5%
(SD 3.9%) in 2018. We also find that areas with few and smaller polling
stations had significantly inflated vote and turnout numbers, again, in favour
of Erdogan. Our results suggest that Turkish elections continue to be riddled
with statistical irregularities, which may be indicative of electoral fraud
The effects of citalopram and low-dose risperidone on memory and anxiety in rats subjected to chronic immobilization stress
OBJECTIVES: Many clinical reports describe the beneficial effects of low-dose atypical antipsychotic added to the antidepressants in the management of anxiety disorders. The aim of this study was to evaluate the effect of low-dose atypical antipsychotic when added to antidepressant treatment on cholinergic M1 receptor expression in the hippocampus and amygdale region in learning and cognitive disorders caused by anxiety. METHODS: The treatments were administered by using different test models on memory, learning, and anxiety, as well as the effect on muscarinic M1 receptor expression levels were assessed. Citalopram (10 mg/kg/sc) and combination [citalopram and risperidone (1 mg/kg/sc)] treatments were applied after stress induction using the immobilization model in rats. Animals groups were randomly divided as: control, stress, stress + citalopram, and stress + combination treatment group. Rats in stress groups were immobilized in cages for 4 h a day for 15 days. On days 1–5, groups were subjected to Morris water maze (MWM), open field, and elevated plus maze (EPM) tests. RESULTS: MWM test results have shown that citalopram induces an anxiolytic effect. Low-dose risperidone treatment has increased the antidepressant-like activity of citalopram in all tests. In OFT the number of squares that rats were circulating on the plane was increased and the time spent by the rats on the maze platform was also increased in MWM. In addition to this, the time spent by the rats on the open arms of the EPM test were also increased. Since the combined treatment increased the discovery of the environment and the active behaviour in tests; all those reflected the increase in general activity. Findings also suggest that treatments may play an effective role in altering the expression level of M1 receptors which are effective in learning and recalling information in the amygdale and the hippocampus. Combination treatment has been shown to provide a meaningful correction of stress-induced memory and learning functions. CONCLUSIONS: These findings indicate that combination treatment may help reduce the stress-induced impairments in cognitive functions
Epidural anesthesia may attenuate lipid peroxidation during aorto-femoral surgery
Purpose: To determine the effect of epidural anesthesia (FP) on oxygenation of the chronically ischemic limb in patients undergoing aorto-femoral bypass grafting and to assess whether it produces an alteration of lipid peroxidation and antioxidant status following revascularization