The place of D-dimer and L-lactate levels in the early diagnosis of acute mesenteric ischemia

INTRODUCTION: Acute mesenteric ischemia (AMI) is an abdominal-vascular emergency which is rare and has high mortality rates (60-80 %) due to late diagnosis (1-3). Although it is known that extravascular reasons like intestinal intussusception, volvulus, strangulated hernias and obstructions can cause intestinal gangrene, these are rarely the cause of AMI (1). MATERIALS AND METHODS: In this study, we used male Wistar-Albino rats weighing 250-300 grams obtained from Pamukkale University Experimental Research Laboratory. Animals were exposed to light-dark cycles for 12 hours and had free access to food and water. They were kept in cages for 7 days to stabilise their intestinal flora. In animals of group I, nothing was made other than taking 0.5 ml blood intracardially. In other animals, abdomen was reached with midline laparotomy and superior mesenteric artery (SMA) was located. In group II (operative control group), SMA was isolated and manipulated but was not ligated. In Group III (intestinal ischemia group), SMAwas isolated and ligated with 3/0 silk tie distally to the aorta. After this process, intestinal ischemia was achieved which was confirmed by paleness and pulselessness of intestines, caecum and right colon. Later on, abdomen was closed with double 3/0 polyglactin sutures. At postoperative 1st, 4th and 6th hours 0.5 ml blood was taken intracardially from the animals in groups II and III in order to quantify D-dimer and L-lactate levels. LABORATORY TESTS: D-dimer: Blood samples which were put into tubes containing sodium citrate, were seperated from plasma with centrifugation at 4000 rpm for 7 minutes. L-lactate: Blood L-lactate levels were determined from blood taken into capillary tubes with the help of immobilised enzyme electrode technology using YSI 1500 Sport portative lactate analyzer (Yellow Springs Instruments Inc., Ohio-USA). HISTOPATHOLOGIC VERIFICATION: Two cm long intestinal samples were taken from animals in which SMA was ligated in order to achieve mesenteric ischemia and these samples were fixed in 10 % formol. DISCUSSION: As a result, in rats with SMA occlusion serum D-dimer levels were not increased significantly when compared either in the group or with the basal values of the control group and values in operative control group. Therefore, it is concluded that D-dimer is not a useful marker for early diagnosis of AMI. On the other hand, it is revealed that blood L-lactate levels began to increase significantly following 4th hour of mesenteric ischemia and it is shown that this increase continued at the 6th hour. In addition, considering the utmost importance of the early diagnosis in patients with the clinical suspicion of AMI, L-lactate seems to be a suitable marker to use in emergency departments because it is achieved with a portable device that gives fast and accurate results. Nevertheless, our results are need to be supported by clinical studies with larger patient series (Tab. 2, Fig. 11, Ref. 39). Text in PDF www.elis.sk

GOALS OF BEEF CATTLE AND DAIRY PRODUCERS: A COMPARISON OF THE FUZZY PAIR-WISE METHOD AND SIMPLE RANKING PROCEDURE

Beef and dairy producers' goal hierarchies over seven goals are compared using fuzzy pair-wise comparison and simple ranking methods. Results show the two methods do not provide similar goal rankings. Producers place greater importance on some goals than others, but are not in agreement as to the relative importance of goals.Livestock Production/Industries,

Symmetry breaking and strong coupling in planar optical metamaterials

We demonstrate narrow transmission resonances at near-infrared wavelengths utilizing coupled asymmetric split-ring resonators (SRRs). By breaking the symmetry of the coupled SRR system, one can excite dark (subradiant) resonant modes that are not readily accessible to symmetric SRR structures. We also show that the quality factor of metamaterial resonant elements can be controlled by tailoring the degree of asymmetry. Changing the distance between asymmetric resonators changes the coupling strength and results in resonant frequency tuning due to resonance hybridization

Environmental urbanization assessment using gis and multicriteria decision analysis: a case study for Denizli (Turkey) municipal area

In recent years, life quality of the urban areas is a growing interest of civil engineering. Environmental quality is essential to display the position of sustainable development and asserts the corresponding countermeasures to the protection of environment. Urban environmental quality involves multidisciplinary parameters and difficulties to be analyzed. The problem is not only complex but also involves many uncertainties, and decision-making on these issues is a challenging problem which contains many parameters and alternatives inherently. Multicriteria decision analysis (MCDA) is a very prepotent technique to solve that sort of problems, and it guides the users confidence by synthesizing that information. Environmental concerns frequently contain spatial information. Spatial multicriteria decision analysis (SMCDA) that includes Geographic Information System (GIS) is efficient to tackle that type of problems. This study has employed some geographic and urbanization parameters to assess the environmental urbanization quality used by those methods. The study area has been described in five categories: very favorable, favorable, moderate, unfavorable, and very unfavorable. The results are momentous to see the current situation, and they could help to mitigate the related concerns. The study proves that the SMCDA descriptions match the environmental quality perception in the city. © 2018 Erdal Akyol et al

Beef Producer Choice in Cattle Marketing

In addition to the conventional auction method of cattle marketing, some alternative marketing arrangements include sale by private treaty, video auction, retained ownership, and use of strategic alliances. This study finds that 91% of Louisiana producers use conventional auctions, while 39% use other types of marketing arrangements. The most heavily used alternative marketing arrangement is private treaty, at 26%. Those producers using alternative marketing arrangements tend to be larger, have heavier weaning weights, have more diverse farming operations, be younger, have greater contact with their county extension agents, and depend less on income from off-farm sources.cattle marketing, conventional auction, private treaty, strategic alliance, video auction, Livestock Production/Industries, Marketing,