The role of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, crp and albumin to predict postoperative one-year mortality in patients with hip fractures

Elderly patients are espcialy at high risk for postoperative complications. This is even more important following hip fracture surgery due to its fragility and comorbidities. Using certain biomarkers may be an interesting way of tackling the question of optimal patient management. In this study we aimed to determine the status of values such as NLR, PLR, albumin, and CRP, which can be easily accessed from blood tests that we routinely use, in predicting mortality in patients who underwent partial prosthesis after hip fractures. Patients over 70 years of age with intertrochanteric femur and collum femoris fractures and who underwent partial endoprosthesis were included in the study. The neutrophil lymphocyte and platelet lymphocyte ratios, albumin values, and CRP values were recorded by examining the hemogram and biochemistry tests taken routinely at the time of admission to the hospital, 1 day before the surgery and on the 1st post-operative day. The distribution of clinical and socio-demographic characteristics of individuals according to their survival within the scope of the study has elaborated that there is a statistically significant difference in terms of age, gender, diagnosis, time to surgery (days) of the deceased and surviving individuals. It is observed that the majority of the patients who died were women and were diagnosed with collum femoris. It was determined that there was a statistically significant difference only in CRP and albumin values between the two groups in postoperative parameters. According to the outcomes of this analysis one can conclude that NLR and PLR values measured preoperatively on the hemogram panel can be used to predict 1-year mortality. Regardless of the fracture period, low albumin value is seen as an independent variable in predicting mortality. [Med-Science 2022; 11(2.000): 729-33

Is the proximal femoral nail a favourable option for trochanteric femur fractures in osteopenic elderly patients?

Primary aim of this study to evaluate the functional results and complications of the patients aged 70 and over whom are treated with proximal femoral nail (PFN) because of hip fracture. 128 patients out of 223 patients were included in the study, who were aged 70 and over, to whom treated with proximal femoral nail because of hip fracture in our clinic between 2006 and 2014. Since 26 of these 128 patients who were included in this study passed away before the follow up period of 1 year, they were excluded from the study. Fractures were evaluated by AO/OTA classification. Their Singh index and morphological cortical indexes were calculated from the pre-surgery radiographies. The functional situations of the patients were evaluated by Harris hip score. Average age of the evaluated 102 patients was 81.13 (70-98), 44 of them were male, 58 of them were female. According to AO/OTA fracture classification 48 of them were 31-A1, 25 of them were 31-A2, 29 of them were 31-A3. 54 fractures were on the left hip, 48 fractures were on the right hip. Average Singh index was 2.72 (1-5), average morphological cortical index was 2.94 (2.1-3.7), average Harris hip score was 74.3 (49-88). 4 patients have had complications after surgery and revised with other treatment modalities. Since the functional results are on a satisfactory level, in our opinion as well, proximal femoral nail should be considered among the surgical treatments in the elderly patients with hip fracture. [Med-Science 2023; 12(2.000): 378-82

Acute effects of Red Bull energy drink on ventricular repolarization in healthy young volunteers: a prospective study

Objective: Energy drinks (EDs) are widely consumed products of the beverage industry and are often chosen by teenagers and young adults. Several adverse cardiovascular events and malignant cardiac arrhythmias following consumption of EDs have been reported in the literature. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the dispersion of repolarization and that an increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. This study investigated the acute effects of Red Bull ED on ventricular repolarization as assessed by the Tp-e interval and Tp-e/QT ratio