Molecular characteristics of 94 MRSA isolates.

*<p>MLST and CC was deducted from PFGE pattern after at least one isolate representative of each PFGE pattern was submitted to MLST typing.</p><p>n-numer of isolates,ery- erythromycin, cli- clindamycin, fus- fusidic acid, gen- gentamicin, tri- trimethoprin/sulfamethoxazole, min- minocycline, R-resistance, I- intermediate resistance, S- susceptibility.</p

Distribution of MLSTs among MRSA and MSSA isolates tested.

<p>Black – MRSA, Grey- MSSA, striped – ST22.</p

Molecular relatedness of ST22 isolates in this survey.

<p>Dendrogram of all isolates corresponding to ST22, by deduction from PFGE patterns (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042864#s2" target="_blank">Methods</a>), including MRSA SSC<i>mec</i> IV and V, MSSA and EMRSA-15 isolate as a reference strain.</p

Molecular characterization and relatedness of MRSA isolates carried by parent-child pairs.

<p>Molecular characterization and relatedness of MRSA isolates carried by parent-child pairs.</p

Predictors for <i>S. aureus</i> and MRSA acquisition among children in Gaza, by multivariate analyses.

*<p>Multivariate model for child <i>S. aureus</i> carriage included: being a cat owner, parental <i>S. aureus</i> carriage, day care center attendance, number of household members, child sex and age.</p>**<p>% from <i>S. aureus carriers</i>.</p>$<p>Multivariate model for child MRSA carriage included: child age, sex and parental MRSA carriage.</p>+<p>Models adjusted as described above.</p

Predictors of <i>S. pneumoniae</i> carriage in children in the Gaza strip.

*<p>N = total number of children with the specified predictor.</p>**<p>% <i>S. pneumoniae</i> carriage among children with the specific predictor.</p

<i>S. pneumoniae</i> carriage by age and by PCV7 vaccine type (VT7) serotypes, serotypes added to PCV7 in PCV10 (a-VT10), serotypes added to PCV10 in PCV13 (a-VT13).

<p>Light grey-VT7 serotype carriage. Dark grey-a-VT10 (1, 5, 7F), Black – a-VT13 (3, 6A, 19A), White - Non-VT13 carriage.</p

Prevalence of antibiotic resistance among isolates.

<p>Black - children. Grey - Parents. PNSSP: penicillin non-susceptible <i>S. pneumoniae</i> (MIC>0.06 mg/L), PRSP: penicillin resistant <i>S. pneumoniae</i> (MIC≥2.0 mg/L), ERSP: erythromycin resistant <i>S. pneumoniae</i> (MIC>0.5 mg/L), TMP/SXTR-SP: trimethoprim-sulfamethoxazolenon-susceptible <i>S. pneumoniae</i> (MIC>0.5 mg/L),MDR-SP: multi-drug resistant <i>S. pneumoniae</i>, defined as non-susceptible to at least penicillin and erythromycin.</p

Potential coverage of antibiotic resistant strains in children by PCV7 (Light Grey), PCV10 (Light+Dark Grey) and PCV13 (Light+Dark Grey+Black).

<p>PSSP: penicillin susceptible <i>S. pneumoniae</i>, PNSSP: penicillin non-susceptible <i>S. pneumoniae</i> (MIC>0.06 mg/L), PRSP: penicillin resistant <i>S. pneumoniae</i> (MIC≥2.0 mg/L), MDR-SP: multi-drug resistant <i>S. pneumoniae</i>, defined as non-susceptible to at least penicillin and erythromycin.</p