B cell epitope mapping across four MOMPs in <i>Chlamydia</i> infected koalas after administration with placebo or vaccine.

<p>Response profile of a <i>C</i><i>. pecorum</i> F infected koala administered with a placebo (adjuvant only) across our MOMP peptide library (<b>A</b>). Response profiles of a naturally infected <i>C</i><i>. pecorum</i> G koala immunized with recombinant MOMP G (<b>B</b>), and a naturally infected <i>C</i><i>. pecorum</i> F koala immunized with recombinant MOMP G (<b>C</b>) across our MOMP peptide library. The blue line represents the absorbance of the pre-immunized sample. The red line represents the 20 weeks post-immunized sample. The green line indicates the background (Mean and two times standard deviation of negative controls).</p

B cell epitope mapping across four MOMPs in naturally, <i>C</i><i>. pecorum</i> genotype G infected koalas.

<p>Response profiles of two wild koalas naturally infected with <i>C</i><i>. pecorum</i> G, Popeye (<b>A</b>) and Mars Bar (<b>B</b>) across MOMP peptide library and amino acid alignment of four MOMPs at VD4 epitope (<b>C</b>) (dots represent the consensus). Representative blot of plasma from the koalas infected with <i>C</i><i>. pecorum</i> G against four recombinant full length MOMP proteins (<b>D</b>). The blue line indicates the mean of absorbance of four <i>Chlamydia</i> free animals. The red line indicates the <i>Chlamydia</i> infected animal. The green line indicates the background (Mean and two times standard deviation of negative controls).</p

B cell epitope mapping across four MOMPs in naturally, <i>C</i><i>. pecorum</i> genotype F infected koalas.

<p>Response profiles of two wild koalas naturally infected with <i>C</i><i>. pecorum</i> F, Nixon (<b>A</b>) and Felix Pitt (<b>B</b>) across MOMP peptide library. Alignment of four MOMPs at an epitope at variable domain two (<b>C</b>), and two overlapping epitopes at variable domain four (<b>D</b>) (dots represent the consensus). The blue line indicates the mean of absorbance of four <i>Chlamydia</i> free animals. The red line indicates the <i>Chlamydia</i> infected animal. The green line indicates the background (Mean and two times standard deviation of negative controls).</p