6,159 research outputs found
Promoting Inclusivity in the Archive: A literature review reassessing tradition through theory and practice
The call for social justice and rise of postmodernism in the second half of the 20th century forced the critical re-evaluation of the traditional archive and its presumed neutral role in the collection and creation of history. Reappraisal of traditional archive theory and practice was forced by heightened critical conscious among the field and its constituents. This literature review examines contemporary methodologies and methods influenced by the postmodern movement and call for social justice in the archive. Affect theory, radical empathy, and queer/ed methodology provide new frameworks for the thinking about the archive space and work towards the creation of a more diverse and inclusive archive. The collection of oral histories and participatory, community archiving practices provide concrete methods for employing the aforementioned theories. This paper purports that these ideas may be better framed within the context of the post-postmodern movement of metamodernism and calls for the continual evaluation of archival theory and practice within this vein
Book Review of Heather McCrea, Diseased Relations: Epidemic, Public Health, and State-Building in Yucatán, Mexico, 1847-1924
Diseased Relations is an impressive work succinct in its focus on the topic of public health history in the Mexican state of Yucatán. Adding to a growing body of scholarship on the nineteenth and early twentieth centuries, this book offers a new lens through which to consider the mechanics of state formation. In this turn to the study of disease and public health, McCrea pulls in the unfolding story of science’s understanding of the origin and spread of diseases and reflects upon the dialogue between national officials and state or local officials in the Yucatán. By choosing to focus on specific disease campaigns, McCrea extends the common discussion of state formation and casts it into a light of intimacy and personal level as she explores the ways in which disease prevention touched and changed the lives of individuals. Instead of viewing ‘nation-building’ through abstractions, she adroitly pursues the palpable and deadly topic of disease and efforts to combat epidemics as a clear implementation of the long-arm of the state into the private lives of individuals
Connecting Seniors in Franklin County Vermont to Community Resources
Vermont currently has the second oldest population in the country and the elderly population is continuing to increase. Senior citizens define aging successfully as having good health, strong friendships, and being able to participate in activities. In order to meet the needs of seniors it is important to find ways to better connect them with available community resources. The aim of this project was to create a pamphlet of community resources available to seniors in Franklin County, Vermont to aid in connecting them to community involvement and support.https://scholarworks.uvm.edu/fmclerk/1274/thumbnail.jp
Monstrous Mobility in Dr. Jekyll and Mr. Hyde and Dracula
This thesis explores Late Victorian Gothic texts that are central to theories on monstrosity in terms of mobility by examining Dr. Jekyll and Mr. Hyde and Dracula. The goal of this project is to survey the ways in which two exemplary monsters, Mr. Hyde and Count Dracula, promote mobility for others and themselves as an inherent part of their monstrosity. The variety of this mobility is demonstrated by examples showing how monsters move and encourage movement in ways that are social and transformative as well as physical. Because social mobility is essential to these movements, this study also considers the societies these monsters enter and interrupt. The gentleman bachelors of Dr. Jekyll and Mr. Hyde and Dracula\u27s Crew of Light and the women they seek to protect are presented as monolithic groups that the monster joins, transforms, and spurs into movement. By identifying mobility as one of the main attributes of monstrosity, this argument seeks to not only add to the copious amount of scholarship already done on these works but also to reconcile some of them since many of the most critically controversial aspects of these texts are rooted in the monster\u27s mobility. A study focused on movement not only adds something that is missing from the existing discussion on these seminal monsters but also provides a new framework through which to discuss constantly evolving theories of monstrosity
Subverting sterols: rerouting an oxysterol-signaling pathway to promote tumor growth.
Oxysterols are oxidized derivatives of cholesterol that are generated enzymatically or through autoxidation. Initially identified as important lipid signaling molecules in the context of atherosclerosis and inflammation, accumulated evidence indicates that these lipid-signaling molecules can have pleiotropic effects on the fate and function of the immune system. These effects range from the regulation of immune cell survival and proliferation to chemotaxis and antiviral immunity. New studies now indicate that tumor-derived oxysterols can serve to subvert the immune system by recruiting protumorigenic neutrophils into the tumor microenvironment. The consequence of this recruitment is the generation of proangiogenic factors and matrix metalloproteinase proteins that provide a tumor a significant growth and survival advantage. In combination with other recent studies, these data highlight the ongoing cross talk between sterol metabolism and the immune system, and they raise the intriguing possibility that targeting oxysterol pathways could serve as a novel therapeutic approach in the war on cancer
- …
