The devil is in the details: Genomics of transmissible cancers in Tasmanian devils - Fig 2

<p>Karyotypes of a normal female Tasmanian devil (top) with a representative karyotype of DFT1 (middle) and DFT2 (bottom). Karyotypes of the Tasmanian devil and DFT1 follow [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007098#ppat.1007098.ref019" target="_blank">19</a>]; this arrangement differs from [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007098#ppat.1007098.ref010" target="_blank">10</a>] in respect to Chromosomes 1 and 2, in which the positions are reversed. Colors in rearranged/fragmented chromosomes indicate the chromosome from which the material originated in the normal devil karyotype. M1–M5 indicate marker chromosomes resulting from fragmentation of Chromosome 1 and fusion with Chromosomes 5 and 1 in DFT1. Asterisks indicate those chromosomes/markers that have been observed to vary among karyotyped strains of DFT1. DFT2 originated from a male devil and thus possesses a Y chromosome. While one copy of Chromosome 6 has been inserted into the pericentric region of Chromosome 1, the limited available karyotypes of DFT2 thus far suggest it is otherwise relatively undifferentiated from the normal devil karyotype. DFT, devil facial tumor.</p