2 research outputs found

    ET and LT modulate MoDCs cytokines secretions.

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    <p>MoDCs were infected with different strains of <i>B. anthracis</i>: RP42 (LT−/ET−), Sterne (LT+/ET+), RP9 (LT+/ET−), or RP10 (LT−/ET+) (A); or pre-treated with purified toxins, and then infected with the non-toxinogenic RP42 strain (B). Data show mean Il-12p70, IL-10, and TNF-α concentrations in culture supernatants (+/−SD) representative of three independent experiments. (C) MoDCs were pre-treated with a different range of purified ET concentrations (1, 10 and 40 ng/ml), and then infected with the non-toxinogenic RP42 strain. Data show mean Il-12p70, IL-10, and TNF-α concentrations in culture supernatants (+/−SD) representative of three independent experiments. Student <i>t-test</i>; <i>*, p<0.05; **, p<0.001</i> as compared with RP42 infected cells. NI: not infected.</p
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