133 research outputs found
Processing of functional fine scale ceramic structures by ink-jet printing
International audienceThis review illustrates the potentiality of ink-jet printing for the fabrication of functional fine scale ceramic structures corresponding to two different kinds of micro-pillar arrays i.e. (i) PZT skeletons, etc..
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derived neutrophil to lymphocyte ratio dnlr change between baseline and cycle 2 is correlated with benefit during immune checkpoint inhibitors ici in advanced non small cell lung cancer nsclc patients
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Parameter Estimation for Personalization of Liver Tumor Radiofrequency Ablation
International audienceMathematical modeling has the potential to assist radiofrequency ablation (RFA) of tumors as it enables prediction of the extent of ablation. However, the accuracy of the simulation is challenged by the material properties since they are patient-specific, temperature and space dependent. In this paper, we present a framework for patient specific radiofrequency ablation modeling of multiple lesions in the case of metastatic diseases. The proposed forward model is based upon a computational model of heat diffusion, cellular necrosis and blood flow through vessels and liver which relies on patient images. We estimate the most sensitive material parameters, those need to be personalized from the available clinical imaging and data. The selected parameters are then estimated using inverse modeling such that the point to-mesh distance between the computed necrotic area and observed lesions is minimized. Based on the personalized parameters, the ablation of the remaining lesions are predicted. The framework is applied to a dataset of seven lesions from three patients including pre- and post-operative CT images. In each case, the parameters were estimated on one tumor and RFA is simulated on the other tumor(s) using these personalized parameters, assuming the parameters to be spatially invariant within the same patient. Results showed significantly good correlation between predicted and actual ablation extent (average point-to-mesh errors of 4.03 mm)
Deletion of the entire interferon-Îł receptor 1 gene causing complete deficiency in three related patients
A new vibration damping method using a semi-passive control
A new damping system, based on piezoceramics shunted with a specific time sequence, is presented: Unlike ofher passive devices, the dissipation does nof occur in a resistance or in a resistor/inductor circuit. The basic idea is to adequately deform the piezo output voltage waveform in order to create a phase shift between the output voltage and the mechanical displacement. The voltage distortion is obtained by switching from short circuit to an open circuit configuration in a repetitive sequence synchronous with the mofion. The switching removes periodically the electric charges from the piezoelectric elements, changes the mechanical overall stiffness and creates non-linearities, thus creating several dissipations mechanisms. Experiments have been run on a cantilever device equipped with ceramic plates and a switching network. The results show a damping level higher that what is achievable with a passive circuit approach. Furthermore, the proposed approach works over a large bandwidth thus leading to important reduction for transient vibration
L'Egfl7 (VE-Statine) diminue la néovasculogenÚse induite par les progéniteurs endothéliaux humains
PARIS-BIUP (751062107) / SudocSudocFranceF
Long-term effects (5 days) of Ćstradiol, T3 or insulin injections on plasma concentrations and estimated hepatic balance of metabolites in energy-deprived preruminant calves
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Short-term effects of oestradiol, T3 or insulin infusions on plasma concentrations and estimated hepatic balances of metabolites in energy-deprived preruminant calves
A soluble nadimide end-capped fluorinated resin
International audienceDiglyme-soluble flurinated nadimide end-capped oligomers were prepared by two distincts routes and were characterized by their molecular weight distribution and their rheological behavior. The thermomechanical behavior of polymerized films and four-ply laminates were examined to study the potential properties of these resins as matrix for composites. The storage modulus G' of the laminates was 5.2 GPa at room temperature and showed good constancy up to 300°
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