377 research outputs found

    On Lattice QCD with Many Flavors

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    We discuss the confining and chiral-symmetry breaking properties of QCD with a large number of flavors NfN_f. In a Monte Carlo simulation of QCD with Nf=16N_f =16 staggered fermions, we find clear evidence of a first order bulk phase transition which separates phases with broken and unbroken chiral symmetry. This is consistent with extrapolations of earlier studies with smaller NfN_f, and is also as expected from general arguments. Thus, even when the perturbative renormalization group flow has a new infrared stable fixed point near the origin, lattice artifacts induce chiral symmetry breaking, and presumably confinement, at sufficiently strong coupling.Comment: 10 pages, LaTeX, figures part of the LaTeX fil

    Asymptotic Behavior of the Correlator for Polyakov Loops

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    The asymptotic behavior of the correlator for Polyakov loop operators separated by a large distance RR is determined for high temperature QCD. It is dominated by nonperturbative effects related to the exchange of magnetostatic gluons. To analyze the asymptotic behavior, the problem is formulated in terms of the effective field theory of QCD in 3 space dimensions. The Polyakov loop operator is expanded in terms of local gauge-invariant operators constructed out of the magnetostatic gauge field, with coefficients that can be calculated using resummed perturbation theory. The asymptotic behavior of the correlator is exp(MR)/R\exp(-MR)/R, where MM is the mass of the lowest-lying glueball in (2+1)(2+1)-dimensional QCD. This result implies that existing lattice calculations of the Polyakov loop correlator at the highest temperatures available do not probe the true asymptotic region in RR.Comment: 10 pages, NUHEP-TH-94-2

    The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes

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    Most cancer types exhibit aberrant transcriptional activity, including derepression of retrotransposable elements (RTEs). However, the degree, specificity and potential consequences of RTE transcriptional activation may differ substantially among cancer types and subtypes. Representing one extreme of the spectrum, we characterize the transcriptional activity of RTEs in cohorts of esophageal adenocarcinoma (EAC) and its precursor Barrett's esophagus (BE) from the OCCAMS (Oesophageal Cancer Clinical and Molecular Stratification) consortium, and from TCGA (The Cancer Genome Atlas). We found exceptionally high RTE inclusion in the EAC transcriptome, driven primarily by transcription of genes incorporating intronic or adjacent RTEs, rather than by autonomous RTE transcription. Nevertheless, numerous chimeric transcripts straddling RTEs and genes, and transcripts from stand-alone RTEs, particularly KLF5- and SOX9-controlled HERVH proviruses, were overexpressed specifically in EAC. Notably, incomplete mRNA splicing and EAC-characteristic intronic RTE inclusion was mirrored by relative loss of the respective fully-spliced, functional mRNA isoforms, consistent with compromised cellular fitness. Defective RNA splicing was linked with strong transcriptional activation of a HERVH provirus on Chr Xp22.32 and defined EAC subtypes with distinct molecular features and prognosis. Our study defines distinguishable RTE transcriptional profiles of EAC, reflecting distinct underlying processes and prognosis, thus providing a framework for targeted studies

    Heavy Quark Free Energies and Screening in SU(2) Gauge Theory

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    We investigate the singlet, triplet and colour average heavy quark free energies in SU(2) pure gauge theory at various temperatures T. We focus on the long distance behaviour of the free energies, studying in particular the temperature dependence of the string tension and the screening masses. The results are qualitatively similar to the SU(3) scenario, except near the critical temperature Tc of the deconfining transition. Finally we test a recently proposed method to renormalize the Polyakov loop.Comment: 5 pages, 4 figures, contribution to the Proceedings of SEWM 2002 (Heidelberg

    Quasimolecular JtetJ_{\rm tet}=3/2 moments in the cluster Mott insulator GaTa4_4Se8_8

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    Quasimolecular orbitals in cluster Mott insulators provide a route to tailor exchange interactions, which may yield novel quantum phases of matter. We demonstrate the cluster Mott character of the lacunar spinel GaTa4_4Se8_8 using resonant inelastic x-ray scattering (RIXS) at the Ta L3L_3 edge. Electrons are fully delocalized over Ta4_4 tetrahedra, forming quasimolecular JtetJ_{\rm tet}=3/2 moments. The modulation of the RIXS intensity as function of the transferred momentum q allows us to determine the cluster wavefunction, which depends on competing intracluster hopping terms that mix states with different character. This mixed wavefunction is decisive for the macroscopic properties since it affects intercluster hopping and exchange interactions and furthermore renormalizes the effective spin-orbit coupling constant. The versatile wavefunction, tunable via intracluster hopping, opens a new perspective on the large family of lacunar spinels and cluster Mott insulators in general.Comment: 7 pages, 4 figures, plus supplementary informatio

    Quarkonium Suppression

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    I discuss quarkonium suppression in equilibriated strongly interacting matter. After a brief review of basic features of quarkonium production I discuss the application of recent lattice data on the heavy quark potential to the problem of quarkonium dissociation as well as the problem of direct lattice determination of quarkonium properties in finite temperature lattice QCD.Comment: Invited plenary talk presented on 4th International Conference on Physics and Astrophysics of Quark Gluon Plasma (ICPAQGP-2001), November 26-30, 2001, Jaipur; 12 pp, LaTeX, uses pramana.st
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