Lifestyle carbon footprints and changes in lifestyles to limit global warming to 1.5 °C, and ways forward for related research

This paper presents an approach for assessing lifestyle carbon footprints and lifestyle change options aimed at achieving the 1.5 °C climate goal and facilitating the transition to decarbonized lifestyles through stakeholder participatory research. Using data on Finland and Japan it shows potential impacts of reducing carbon footprints through changes in lifestyles for around 30 options covering food, housing, and mobility domains, in comparison with the 2030 and 2050 per-capita targets (2.5-3.2 tCO2e by 2030; 0.7-1.4 tCO2e by 2050). It discusses research opportunities for expanding the footprint-based quantitative analysis to incorporate subnational analysis, living lab, and scenario development aiming at advancing sustainability science on the transition to decarbonized lifestyles

Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases

Mitochondrial dysfunction increases oxidative stress and depletes ATP in a variety of disorders. Several antioxidant therapies and drugs affecting mitochondrial biogenesis are undergoing investigation, although not all of them have demonstrated favorable effects in the clinic. We recently reported a therapeutic mitochondrial drug mitochonic acid MA-5 (Tohoku J. Exp. Med., 2015). MA-5 increased ATP, rescued mitochondrial disease fibroblasts and prolonged the life span of the disease model “Mitomouse” (JASN, 2016). To investigate the potential of MA-5 on various mitochondrial diseases, we collected 25 cases of fibroblasts from various genetic mutations and cell protective effect of MA-5 and the ATP producing mechanism was examined. 24 out of the 25 patient fibroblasts (96%) were responded to MA-5. Under oxidative stress condition, the GDF-15 was increased and this increase was significantly abrogated by MA-5. The serum GDF-15 elevated in Mitomouse was likewise reduced by MA-5. MA-5 facilitates mitochondrial ATP production and reduces ROS independent of ETC by facilitating ATP synthase oligomerization and supercomplex formation with mitofilin/Mic60. MA-5 reduced mitochondria fragmentation, restores crista shape and dynamics. MA-5 has potential as a drug for the treatment of various mitochondrial diseases. The diagnostic use of GDF-15 will be also useful in a forthcoming MA-5 clinical trial

Introduction for Fisheries and Aquatic Biology

Chapter I. Aquatic Environment. Ken FURUYA and Ichiro YASUDA : chapter_1.pdfChapter II. Biology and Ecology of Aqua-Shere. Toyoji KANEKO, Katsumi TSUKAMOTO, Atsushi TSUDA, Yuzuru SUZUKI and Katsufumi SATOH : chapter_2.pdfChapter III. Aquatic Resource and Production. Ichiro AOKI, Kazuo OGAWA, Taku YAMAKAWA and Tomoyoshi YOSHINAGA : chapter_3.pdfChapter IV. Chemistry of Aquatic Organism and Their Utilization. Hiroki ABE, Shugo WATABE, Yoshihiro OCHIAI, Shigeru OKADA, Naoko YOSHIKAWA, Yoshiharu KINOSHITA, Gen KANEKO and Shigeki MATSUNAGA : chapter_4.pdfChapter V. Relation between Aqua-Shere and Human Life. Hisashi KUROKURA, Hirohide MATSUSHIMA, Shingo KUROHAGI, Haruko YAMASHITA, Akinori HINO, Kazumasa IKUTA, Satoquo SEINO, Masahiko ARIJI, Ken FURUYA, Junichiro OKAMOTO and Nobuyuki YAGI : chapter_5.pdfPart of "Introduction for Fisheries and Aquatic Biology

Implementation of Accelerated Policy-Driven Sustainability Transitions: Case of Bharat Stage 4 to 6 Leapfrogs in India

In the face of pressing environmental challenges, governments must pledge to achieve sustainability transitions within an accelerated timeline, faster than leaving these transitions to the market mechanisms alone. This had led to an emergent approach within the sustainability transition research (STR): Accelerated policy-driven sustainability transitions (APDST). Literature on APDST asserts its significance in addressing pressing environmental and development challenges as regime actors like policymakers enact change. It also assumes support from other incumbent regime actors like the industries and businesses. In this study, we identify the reasons for which incumbent industry and business actors might support APDST and whether their support can suffice for implementation. We examine the actor strategies by drawing empirical data from the Indian national government policy of mandatory leapfrog in internal combustion engine (ICE) vehicle emission control norms, known as Bharat Stage 4 to 6. This leapfrogging policy was introduced to speed up the reduction of air pollutants produced by the transport sector. A mixed-methods approach, combining multimodal discourse analysis and netnographic research, was deployed for data collection and analysis. The findings show that unlike the status quo assumption in STR, many incumbent industry and business actors aligned with the direction of the enacted policy due to the political landscape and expected gains. However, the degree of support varied throughout the transition timeline and was influenced by challenges during the transitioning process and the response of the government actors. The case suggests we pay more attention to the actors’ changing capacities and needs and consider internal and external influences in adapting the transition timelines. This study contributes to the ongoing discussion on the implementation of APDST, by examining the dynamism of actor strategies, and provides an overview of sustainability transitions in emerging economies