Antioxidant and Antifatigue Properties of the Aqueous Extract of Moringa oleifera

The effects of the aqueous extract of Moringa oleifera on swimming performance and related biochemical parameters were investigated in male Wistar rats (130–132 g). Four groups of rats (16 per group) were fed a standard laboratory diet and given distilled water, 100, 200, or 400 mg/kg of extract, respectively, for 28 days. On day 28, 8 rats from each group were subjected to the forced swimming test with tail load (10% of body weight). The remaining 8 rats per group were subjected to the 90-minute free swim. Maximum swimming time, glycemia, lactamia, uremia, triglyceridemia, hepatic and muscle glycogen, hematological parameters, and oxidative stress parameters (superoxide dismutase, catalase, reduced glutathione, and malondialdehyde) were measured. Results. M. oleifera extract increased maximum swimming time, blood hemoglobin, blood glucose, and hepatic and muscle glycogen reserves. The extract also increased the activity of antioxidant enzymes and decreased the blood concentrations of malondialdehyde. Furthermore, it decreased blood concentrations of lactate, triglycerides, and urea. In conclusion, the antifatigue properties of M. oleifera extract are demonstrated by its ability to improve body energy stores and tissue antioxidant capacity and to reduce the tissue build-up of lactic acid

Petrology and geochemical framework of dolerites dykes of Temté, North Cameroon

International audienceThe Temté basement in North Cameroon is crosscut by dyke swarms with N 20°–40° trending, including dykes 15–30 m wide, up to 3 km-long. Representative rocks exhibit intersertal to sub-ophitic textures. Electron microprobe analyses identified diopside, augite, pargasite, biotite, Ti-magnetite, plagioclase, and sanidine. Whole-rock ICP-MS and ICP-AES chemical analyses showed compositions of basaltic andesite, basaltic trachyandesite and trachyandesite in composition. Igneous differentiation was likely governed by fractional crystallization associated with limited fluid metasomatism. Some lavas could have been moderately contaminated by crustal materials during feeding of local cracks through turbulent magma flows. Discrimination geochemical diagrams and immobile trace and REE element ratios show that the mantle source of Temté dolerites was a deep phlogopite-bearing EMII mantle component and has undergone moderate to high partial melting rate. Correlations of fieldwork and analytical data with previous results evidence the Temté dolerite dyke swarms as fingerprints of crustal extension accompanying regional uplift in an active continental margin when early rifting led to the formation of the Poli marginal basin