Cosmic Strings as Emitters of Extremely High Energy Neutrinos

We study massive particle radiation from cosmic string kinks, and its observability in extremely high energy neutrinos. In particular, we consider the emission of moduli --- weakly coupled scalar particles predicted in supersymmetric theories --- from the kinks of cosmic string loops. Since kinks move at the speed of light on strings, moduli are emitted with large Lorentz factors, and eventually decay into many pions and neutrinos via hadronic cascades. The produced neutrino flux has energy $E \gtrsim 10^{11} \rm{GeV}$, and is affected by oscillations and absorption (resonant and non-resonant). It is observable at upcoming neutrino telescopes such as JEM-EUSO, and the radio telescopes LOFAR and SKA, for a range of values of the string tension, and of the mass and coupling constant of the moduli.Comment: 13 pages, 2 figure

Cost-effectiveness of intensive Vs. standard follow-up models for patients with breast cancer in Shiraz, Iran

Background: Breast cancer is the most common type of cancer amongst women throughout the world. Currently, there are various follow-up strategies implemented in Iran, which are usually dependent on clinic policies and agreement among the resident oncologists. Purpose: A cost-effectiveness analysis was performed to assess the cost-effectiveness of intensive follow-up versus standard models for early breast cancer patients in Iran. Materials and methods: This cross sectional study was performed with 382 patients each in the intensive and standard groups. Costs were identified and measured from a payer perspective, including direct medical outlay. To assess the effectiveness of the two follow-up models we used a decision tree along with indicators of detection of recurrence and metastasis, calculating expected costs and effectiveness for both cases; in addition, incremental cost-effectiveness ratios were determined. Results: The results of decision tree showed expected case detection rates of 0.137 and 0.018 and expected costs of US24,494.62 and US6,859.27, respectively, for the intensive and standard follow-up models. Tornado diagrams revealed the highest sensitivity to cost increases using the intensive follow-up model with an ICER=US148,196.2. Conclusion: Overall, the results showed that the intensive follow-up method is not cost-effective when compared to the standard model

Second generation of HIV surveillance system: A pattern for IRAN

Background: For the purpose of minimizing the HIV/AIDS epidemic effects, one of the programs is the promotion of scientific methods and setting of the suitable surveillance systems. The present research was conducted to design the HIV/AIDS surveillance system in Iran applying WHO recommendations and the experience of some countries. Methods: In 2009, based on the country's requirements, the HIV/AIDS surveillance system was proposed and designed for Iran. The Delphi technique was utilized to find the views of experts. Data analysis was conducted based on a comparison of the attributes of the HIV/AIDS surveillance systems in the countries under consideration using a descriptive and theoretical analysis. Results: The model was approved obtaining the final score of 36.3 out of 44, viz 82.5. Conclusion: Designing and performing of the HIV/AIDS surveillance pattern in the direction of "second generation of HIV/AIDS surveillance" can be considered as an important step in the improvement of the patient's control and precaution of HIV/AIDS. © Iranian Red Crescent Medical Journal