Sakroiliiti taklit eden hodgkin lenfoma: Olgu sunumu]

Musculoskeletal syndromes may be associated with neoplastic diseases. We hereby report a case of sacroiliitis that was diagnosed as Hodgkin's lymphoma during the follow-up process. Though sacroiliitis was confirmed with magnetic resonance imaging (MRI), a diagnosis of malignancy associated with sacroiliitis may be delayed and cause a clinical challenge. We aimed to discuss the presentation of lymphoma with sacroiliac joint involvement and its probable mechanisms and review the literature

Paget's disease of the bone: a case report

WOS: 000379526700010Paget's disease of the bone is a chronic disease of unknown etiology that affects mainly elderly population. Genetic and environmental factors play an important role in the pathogenesis of the disease. Paget's disease is characterized by increased bone resorption followed by excessive new bone formation. The diagnosis is usually made incidentally during radiological investigations for other conditions or due to an unexpected elevation of serum alkaline phosphatase. Focal pain in the involved bones is the most common symptom of disease. Nitrogen containing bisphosphonates are first line drugs in the treatment. In this study we present a patient diagnosed with Paget's disease and discussed the features of this disorder which is of importance in the elderly population

Brait-fahn-schwarz disease: Parkinson's disease and amyotrophic lateral sclerosis complex

WOS: 000381980000033PubMed: 26319125Neurodegenerative diseases such as Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) are sometimes present together, as in the Parkinsonism-dementia complex of Guam. Outside the specific geographical regions, the combination of ALS and PD is rare [1]. This neurodegenerative complex was first described by Brait et al. [2] and clinically presents with levodopa responsive parkinsonism followed by AL

The relationship between vitamin D level and lipid profile in patients admitted to physical medicine and rehabilitation outpatient clinic

Amaç: Kardiyovasküler (KVS) hastalıklar, dünya çapında önde gelen ölüm sebeplerindendir. Epidemiyolojik çalışmalarda serum 25 Hidroksi D vitamini (25-OH D) ile KVS hastalık risk faktörlerinden olan lipid profili arasında negatif korelasyon olduğu gösterilmiştir. Bununla birlikte 25-OH D vitamin düzeyi ile hastalık arasındaki ilişkinin nedensel olup olmadığı veya sadece yaşam tarzı ile ilişkili bir belirteç olduğu durumu belirsizdir. Vitamin D takviyesinin serum lipid profili üzerine etkileri araştıran plasebo kontrollü çalışmalar farklı sonuçlar vermiştir. Bu çalışmanın amacı serum vitamin D konsantrasyonu ile lipid profili arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntem: Fiziksel Tıp ve Rehabilitasyon polikliniğine ağrı şikayetiyle başvuran 204 hasta çalışmaya dahil edildi. Hastaların demografik özellikleri kaydedildi. Açlık serum 25-OH D vitamini, total kolesterol, LDL, HDL ve trigliserid konsantrasyonları ölçüldü. Bulgular: Hastaların ortalama 25-OH D düzeyleri 10.66.5 ng/mL, D vitamini eksikliği prevalansı %92.2 idi. Hastalar 25-OH D vitamin düzeylerine göre 20 ng/mL, 20-30 ng/mL ve 30 ng/mL olmak üzere 3 gruba ayrıldı. Yüksek D vitamini konsantrasyonu olan hastalarda D vitamini eksikliği olan hastalara göre serum total kolesterol, TG ve LDL düzeyleri düşük ve HDL düzeyi daha yüksek olmasına rağmen, bu fark istatistiksel olarak anlamlı değildi (p 0.05). Sonuç: D vitamini eksikliği prevalansı ve uygun olmayan lipid profilinin olumsuz etkileri göz önüne alındığında, yüksek riskli toplumlarda D vitamini durumunun incelenmesi, düzeltilmesi ve korunmasının uygun olacağı görüşündeyiz.Aim: Cardiovascular disease (CVD) is one of the leading causes of deaths worldwide. Epidemiological studies have shown an inverse association between serum 25-hydroxy vitamin D (25-OH D) and cardiovascular risk factors including lipid profile. However, it is still unclear whether 25-OH D level is causally related to the disease or is just a marker of lifestyle. Placebo-controlled trials that examined the effect of vitamin D supplementation on serum lipid profile have provided divergent results. The aim of this study is to investigate the relationship between serum vitamin D concentration and lipid profile. Materials and Methods: Two hundred and four patients admitted to physical medicine and rehabilitation outpatient clinic with the complaint of pain were included in this study. The demographic characteristics of patients were recorded. Fasting serum concentrations of 25-OH vitamin D, total cholesterol, high-density lipoprotein (HDL), low- density lipoprotein (LDL) and triglyceride were measured. Results: The mean level of 25-OH D was 10.6±6.5 ng/mL, the prevalence of vitamin D deficiency was 92.2%. Patients were classified into 3 groups according to the 25-OH vitamin D levels as 30 ng/mL. Although in patients with higher vitamin D concentration, serum levels of total cholesterol, TG, and LDL were lower and HDL was higher compared to patients with vitamin D deficiency, this association was not statistically significant (p>0.05). Conclusion: Given the prevalence of vitamin D insufficiency and the detrimental consequences of an unfavorable lipid profile, we believe that investigation, correction, and maintenance of vitamin D status may be indicated in high- risk populations

Temperament and character profile in failed back surgery syndrome: A cross-sectional clinical study

Sengul, Ilker/0000-0002-7675-7814WOS: 000387302000016PubMed: 27476913AIM: Some psychometric properties may predict the development of failed back surgery syndrome (FBSS). The aim of this study was to determine the pain, disability, and depression severity in patients diagnosed with FBSS, and to determine the temperament and character subgroups in comparison with control group. MATERIAL and METHODS: Thirty-eight patients diagnosed with FBSS, and 35 patients with favourable outcome after lumbar spinal surgery were included to the study. Pain intensity, disability, depression scores, temperament and character profile were determined by the visual analogue scale (VAS), Roland Morris Disability Index, Beck Depression Inventory, and Temperament and Character Inventory. RESULTS: Pain intensity, disability, and depression scores were higher in the FBSS group (p<0.001). There were no significant differences between temperament and character subgroups between study groups except one of the temperament subgroup, reward dependence (p=0.05). There was a negative correlation between self-directedness and leg pain severity in the FBSS group (p=0.01, r=-0.400). CONCLUSION: No significant differences were found between the FBSS and control groups with respect to temperament and character profile but FBSS was the cause of severe pain, disability, and higher depression scores. This group of patients must therefore be evaluated psychiatrically and should also be subjected to a clinical examination, and they should be managed using a multidisciplinary approach