Stabilization and precise calibration of a continuous-wave difference frequency spectrometer by use of a simple transfer cavity

A novel, simple, and inexpensive calibration scheme for a continuous-wave difference frequency spectrometer is presented, based on the stabilization of an open transfer cavity by locking onto the output of a polarization stabilized HeNe laser. High frequency, acoustic fluctuations of the transfer cavity length are compensated with a piezoelectric transducer mounted mirror, while long term drift in cavity length is controlled by thermal feedback. A single mode Ar+ laser, used with a single mode ring dye laser in the difference frequency generation of 2–4 µm light, is then locked onto a suitable fringe of this stable cavity, achieving a very small long term drift and furthermore reducing the free running Ar+ linewidth to about 1 MHz. The dye laser scan provides tunability in the difference frequency mixing process, and is calibrated by marker fringes with the same stable cavity. Due to the absolute stability of the marker cavity, precise frequency determination of near infrared molecular transitions is achieved via interpolation between these marker fringes. It is shown theoretically that the residual error of this scheme due to the dispersion of air in the transfer cavity is quite small, and experimentally that a frequency precision on the order of 1 MHz per hour is routinely obtained with respect to molecular transitions. Review of Scientific Instruments is copyrighted by The American Institute of Physics

Probing the electron EDM with cold molecules

We present progress towards a new measurement of the electron electric dipole moment using a cold supersonic beam of YbF molecules. Data are currently being taken with a sensitivity of $10^{-27}\textrm{e.cm}/\sqrt{\textrm{day}}$. We therefore expect to make an improvement over the Tl experiment of Commins' group, which currently gives the most precise result. We discuss the systematic and statistical errors and comment on the future prospect of making a measurement at the level of $10^{-29}\textrm{e.cm}/\sqrt{\textrm{day}}$.Comment: 8 pages, 6 figures, proceedings of ICAP 200

A comparison of A-level performance in economics and business studies: how much more difficult is economics?

This paper uses ALIS data to compare academic performance in two subjects often viewed as relatively close substitutes for one another at A-level. The important role of GCSE achievement is confirmed for both subjects. There is evidence of strong gender effects and variation in outcomes across Examination Boards. A counterfactual exercise suggests that if the sample of Business Studies candidates had studied Economics nearly 40% of those who obtained a grade C or better in the former subject would not have done so in the latter. The opposite exercise uggests that 12% more Economics candidates would have achieved a grade C or better if they had taken Business Studies. In order to render a Business Studies A-level grade comparable to an Economics one in terms of relative difficulty, we estimate that a downward adjustment of 1.5 UCAS points should be applied to the former subject. This adjustment is lower than that suggested by correction factors based on conventional subject pair analysis for these two subjects

Toward a simulation approach for alkene ring-closing metathesis : scope and limitations of a model for RCM

A published model for revealing solvent effects on the ring-closing metathesis (RCM) reaction of di-Et diallylmalonate 7 has been evaluated over a wider range of conditions, to assess its suitability for new applications. Unfortunately, the model is too flexible and the published rate consts. do not agree with exptl. studies in the literature. However, by fixing the values of important rate consts. and restricting the concn. ranges studied, useful conclusions can be drawn about the relative rates of RCM of different substrates, precatalyst concn. can be simulated accurately and the effect of precatalyst loading can be anticipated. Progress has also been made toward applying the model to precatalyst evaluation, but further modifications to the model are necessary to achieve much broader aims

Upper Limits On Periodic, Pulsed Radio Emission from the X-Ray Point Source in Cassiopeia A

The Chandra X-ray Observatory recently discovered an X-ray point source near the center of Cassiopeia A, the youngest known Galactic supernova remnant. We have conducted a sensitive search for radio pulsations from this source with the Very Large Array, taking advantage of the high angular resolution of the array to resolve out the emission from the remnant itself. No convincing signatures of a dispersed, periodic source or of isolated dispersed pulses were found, whether for an isolated or a binary source. We derive upper limits of 30 and 1.3 mJy at 327 and 1435 MHz for the phase-averaged pulsed flux density from this source. The corresponding luminosity limits are lower than those for any pulsar with age less than 10^4 years. The sensitivities of our search to single pulses were 25 and 1.0 Jy at 327 and 1435 MHz. For comparison, the Crab pulsar emits roughly 80 pulses per minute with flux densities greater than 100 Jy at 327 MHz and 8 pulses per minute with flux densities greater than 50 Jy at 1435 MHz. These limits are consistent with the suggestion that the X-ray point source in Cas A adds to the growing number of neutron stars which are not radio pulsars.Comment: accepted by ApJ Letter

Pulsed beams as field probes for precision measurement

We describe a technique for mapping the spatial variation of static electric, static magnetic, and rf magnetic fields using a pulsed atomic or molecular beam. The method is demonstrated using a beam designed to measure the electric dipole moment of the electron. We present maps of the interaction region, showing sensitivity to (i) electric field variation of 1.5 V/cm at 3.3 kV/cm with a spatial resolution of 15 mm; (ii) magnetic field variation of 5 nT with 25 mm resolution; (iii) radio-frequency magnetic field amplitude with 15 mm resolution. This new diagnostic technique is very powerful in the context of high-precision atomic and molecular physics experiments, where pulsed beams have not hitherto found widespread application.Comment: 6 pages, 12 figures. Figures heavily compressed to comply with arxiv's antediluvian file-size polic

C1 inhibitor deficiency: 2014 United Kingdom consensus document

C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient patients, representing a joint venture between the United Kingdom Primary Immunodeficiency Network and Hereditary Angioedema UK. To develop the consensus, we assembled a multi-disciplinary steering group of clinicians, nurses and a patient representative. This steering group first met in 2012, developing a total of 48 recommendations across 11 themes. The statements were distributed to relevant clinicians and a representative group of patients to be scored for agreement on a Likert scale. All 48 statements achieved a high degree of consensus, indicating strong alignment of opinion. The recommendations have evolved significantly since the 2005 document, with particularly notable developments including an improved evidence base to guide dosing and indications for acute treatment, greater emphasis on home therapy for acute attacks and a strong focus on service organisation. This article is protected by copyright. All rights reserved

Coherently Dedispersed Polarimetry of Millisecond Pulsars

We present a large sample of high-precision, coherently-dedispersed polarization profiles of millisecond pulsars (MSPs) at frequencies between 410 and 1414 MHz. These data include the first polarimetric observations of several of the pulsars, and the first low-frequency polarization profiles for others. Our observations support previous suggestions that the pulse shapes and polarimetry of MSPs are more complex than those of their slower relatives. An immediate conclusion is that polarimetry-based classification schemes proposed for young pulsars are of only limited use when applied to millisecond pulsars.Comment: 28 pages, 10 figures. Text matches version that appeared in ApJS. Full paper with high-resolution figures available at ftp://ftp.jb.man.ac.uk/pub/psr/papers/msppolpton.ps.g