Evaluation of serum lipid profile in cases of pre-eclampsia and eclampsia

Background: According to the current knowledge, rise in the serum triglyceride level is a major contributor in the pathogenesis of preeclampsia and eclampsia. The present study was designed to compare the changes in lipid profile in normal pregnancy, pre-eclampsia & eclampsia cases.Methods: A case control study was done consisting of total 100 study subjects, 75 already diagnosed pre-eclamptic & eclamptic women and 25 normotensive pregnant women. Age range was 18-35 years, gestational age 28 weeks to term were included. Serum Total Cholesterol (TC), triglyceride and HDL-cholesterol by enzymatic colorimetric method were done.Results: Results showed that level of serum triglycerides in mild pre-eclampsia (156.22 ± 66.5 mg/dl), severe pre-eclampsia (168.30 ± 68.1 mg/dl) & eclampsia (224.89 ± 84.40 mg/dl) as compared to normal pregnant women (130.95 ± 44.64 mg/dl) was increased significantly (P <0.05). Other parameters TC, HDL-C, LDL-C were not changed significantly.Conclusions: The findings of the present study are consistent with previous studies, suggesting increased levels of serum triglyceride as an important factor in the pathological process of preeclampsia & eclampsia. This may help in developing strategies for prevention or early diagnosis of the disorder

Improve Performance of FAUB Error for Three Phase Power Distribution System

Distribution system issues, similar to loss minimization, planning and energy restoration, in some cases include the phase adjustment. Flawed dispersion will lead few regions full and couple of zones with less stacked. In this way to keep away from these conditions, prevailing of force and subsequently controlling of load is required in those territories. It brings about the load equalization. Load equalization or balancing out is that the system to prevent the system from over burdening situation. Amid this paper we have a tendency to plan and execution of power load adjusting by utilizing mathematical logic (fuzzy logic) tool compartment of a MATLAB. As indicated by past work consequences of Final Absolute Average Unbalance i.e. FAUB/Phase= 3.33kw. We will modify variation of input reliable with fuzzy principle. On the off chance that we plan the standards steady with given principles then the FAUB will be diminishing from 3.33kW. DOI: 10.17762/ijritcc2321-8169.150610

Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner.

Fibronectin (Fn1) is an evolutionarily conserved extracellular matrix glycoprotein essential for embryonic development. Global deletion of Fn1 leads to mid-gestation lethality from cardiovascular defects. However, severe morphogenetic defects that occur early in embryogenesis in these embryos precluded assigning a direct role for Fn1 in cardiovascular development. We noticed that Fn1 is expressed in strikingly non-uniform patterns during mouse embryogenesis, and that its expression is particularly enriched in the pharyngeal region corresponding with the pharyngeal arches 3, 4, and 6. This region bears a special importance for the developing cardiovascular system, and we hypothesized that the localized enrichment of Fn1 in the pharyngeal region may be essential for cardiovascular morphogenesis. To test this hypothesis, we ablated Fn1 using the Isl1(Cre) knock-in strain of mice. Deletion of Fn1 using the Isl1(Cre) strain resulted in defective formation of the 4th pharyngeal arch arteries (PAAs), aberrant development of the cardiac outflow tract (OFT), and ventricular septum defects. To determine the cell types responding to Fn1 signaling during cardiovascular development, we deleted a major Fn1 receptor, integrin α5 using the Isl1(Cre) strain, and observed the same spectrum of abnormalities seen in the Fn1 conditional mutants. Additional conditional mutagenesis studies designed to ablate integrin α5 in distinct cell types within the Isl1(+) tissues and their derivatives, suggested that the expression of integrin α5 in the pharyngeal arch mesoderm, endothelium, surface ectoderm and the neural crest were not required for PAA formation. Our studies suggest that an (as yet unknown) integrin α5-dependent signal extrinsic to the pharyngeal endothelium mediates the formation of the 4th PAAs

An empirical rule for extended range prediction of duration of Indian summer monsoon breaks

Prediction of the duration of the Indian summer monsoon breaks is highly desirable. It will help in planning water resource management, sowing and harvesting. Applicability of the recently discovered regime transition rules for the Lorenz model in predicting the duration of monsoon breaks, is explored in this paper. Using several indices of the observed summer monsoon intraseasonal oscillation (ISO), it is shown that the peak anomaly in an active regime can be used as a predictor for the duration of the subsequent break spell. It is also found that the average growth rate around the threshold to an active condition can be used as a predictor of the peak anomaly in the active spell. Average growth around the threshold to an active condition can give useful prediction of the duration of the following break, on an average, about 23 days (38 days) in advance of its commencement (end)

Impact of human intervention and climate change on natural flow regime

According to the ‘natural flow paradigm’, any departure from the natural flow condition will alter the river ecosystem. River flow regimes have been modified by anthropogenic interventions and climate change is further expected to affect the biotic interactions and the distribution of stream biota by altering streamflow. This study aims to evaluate the hydrologic alteration caused by dam construction and climatic changes in a mesoscale river basin, which is prone to both droughts and monsoonal floods. To analyse the natural flow regime, 15 years of observed streamflow (1950–1965) prior to dam construction is used. Future flow regime is simulated by a calibrated hydrological model Soil and Water Assessment Tool (SWAT), using ensemble of four high resolution (~25 km) Regional Climate Model (RCM) simulations for the near future (2021–2050) based on the SRES A1B scenario. Finally, to quantify the hydrological alterations of different flow characteristics, the Indicators of Hydrological Alteration (IHA) program based on the Range of Variability Approach (RVA) is used. This approach enables the assessment of ecologically sensitive streamflow parameters for the pre- and post-impact periods in the regions where availability of long-term ecological data is a limiting factor. Results indicate that flow variability has been significantly reduced due to dam construction with high flows being absorbed and pre-monsoon low flows being enhanced by the reservoir. Climate change alone may reduce high peak flows while a combination of dam and climate change may significantly reduce variability by affecting both high and low flows, thereby further disrupting the functioning of riverine ecosystems. We find that, in the Kangsabati River basin, influence of dam is greater than that of the climate change, thereby emphasizing the significance of direct human intervention