Cold Water Immersion: A Foe for Immediate Leg Strength Recovery Post Strenuous Activity

Recovery post sport activities of demanding nature has become a matter of great concern in present days. To add information in the knowledge bank regarding the rate and trend in lower limbs tiredness recovery due to cold water immersion (CWI) after strenuous workout present research in a highly controlled manner was conducted. Ten participants of equal caliber were selected purposively for the experiment. They ran at Target Heart Rate Zone of 80%-90% of their Maximum Heart Rate for 20 minutes, and had a session of idle CWI (20?C) post activity for 30 minutes. Isometric Leg Strength Test and Sergeant Jump Test were conducted pre activity, post activity and post CWI for availing data. Descriptive statistics, rANOVA and bonferroni post hoc test were employed using IBM SPSS-17. Level of significance choosen was 0.05. Significant decreased state of post workout readings were observed in both the cases. Further post recovery no improvement in state of lower limbs isometric strength was found, whereas decrease in explosive leg strength was evident. Thus it can be concluded that instead of being friend CWI is a foe for immediate leg strength recovery. In future more research having different and prolonged observation points can be framed to have clear idea on this issue. Keywords: Sports, Recovery, Cold Water Immersion, Isometric Leg Strength, Explosive Leg Strength

Assessment of Airborne Fungi in Childrens Hospital Located in Kolkata India

Fungal spores contribute significant concentration in the bioaerosol of various environmental conditions which may have potential health threats. Our study was aimed at determining the presence of disseminating airborne fungi in a pediatric government hospital in Kolkata. The study was started from the post-monsoon to the middle winter (August to December 2008) in the indoor and outdoor environment of the hospital with temperature and humidity ranges of 11.2 °C-35.2 °C and 70 per cent-90 per cent, respectively. Air sampling was performed at 14 days intervals during the daytime following the gravitation settling method, and the fungal colonies were identified based on micro and macro morphological characteristics. The percentage contribution of individual fungal species from the outdoor section and indoor units (Newborn Baby Ward, Respiratory Care Unit, Step Down Ward, Thalassemia Care Unit) of the hospital environment was calculated. We observed profound aeromycofloral diversity where the outdoor environment was mostly colonised by sterile hyphae (16.43 %) along with the allergenic Aspergillus fumigatus (13.6 %) and Penicillium sp. (12.32 %). Conversely, an abundance of Cladosporium herbarum (24.7 %) and Penicillium sp. (17.85 %) followed by Aspergillus sp. (12.9 %) and sterile hyphae (14.51 %) were found in different indoor units. Our results showed the diversity of airborne mycoflora which promotes the trend to health difficulties and thus the hospital environment monitoring along with proper control measures is essential

Role of Organochlorine Pesticides in Chronic Kidney Diseases of Unknown Etiology

Chronic kidney disease (CKD) contributes to a significant burden on the healthcare system and economy worldwide. In the last two decades, a new form of CKD: chronic kidney disease of unknown etiology (CKDu) in which the disease is not attributed to known causes has emerged as a major health issue in different geographical areas over the world mainly from farming community and has become a global concern today. Despite intense and numerous research works dedicated to CKDu, very little is known with certainty regarding its etiology and the pathophysiology behind its development. Recent evidences are emerging in favor of possible role of agrochemicals and pesticides in the pathogenesis of CKDu. Organochlorine pesticides (OCPs) due to their longer half-life and lipophilic nature persist long in the environment and are known to be biomagnified through food chain. Some study reports by the authors and a few others constitute the important body of evidences depicting the association between chronic exposures to OCPs and occurrence of CKDu through environmental contamination in farming as well as non-farming communities in different geographical areas around the globe

Postprandial Plasma Glucose Responses And Glycaemic Indices Of Different Forms Of A Large Sago Meal.

The aim of the study was to determine the postprandial plasma glucose responses and glycaemic indices of three different physical forms of a sago meal. Twelve healthy subjects consumed in random order, three white bread meals and three sago meals (sago porridge, sago paste and sago gel) on separate days at least 1 week apart after an overnight fast

Antioxidant, antiinflammatory and antiinvasive activities of biopolyphenolics

A large number of polyphenolic and heterocyclic compounds, i.e. 4-methylcoumarins, 4-methylthionocoumarins, xanthones, pyrazoles, pyrazolylacrylonitriles, flavones and isoflavones have been tested for their antioxidant activity towards NADPH-catalysed liver-microsomal lipid peroxidation with a view to establish their structure-activity relationship. Inhibition of microsomal lipid peroxidation by 7,8-dihydroxy-4-methylcoumarin (DHMC, 2) and 7,8-diacetoxy-4-methylcoumarin (DAMC, 3) was intriguing. We also found that dihydroxy and diacetoxy derivatives of 4-methylthionocoumarin were more potent in comparison to the corresponding coumarin derivatives in inhibiting TNF-α induced expression of ICAM-1. The effect of nine different xanthones has been examined on the modulation of cytokine-induced expression of ICAM-1 in human endothelial cells. 1,4-Dihydroxyxanthone (10) showed enhanced antioxidant activity as well as the inhibition of the expression of cell adhesion molecules, such as ICAM-1, VCAM-1 and E-selectin on endothelial cells in a concentration and time dependent manner. Antioxidant activity of different pyrazoles and pyrazolylacrylonitriles and antiinvasive activity of flavones and isoflavones against solid tumors have also been studied

Stranding of dolphins along north Andhra Pradesh coast

On 6th November 2021, a Risso’s Dolphin, Grampus griseus (G. Cuvier, 1812) which measured as 230 cm in total length was stranded on the Rushikonda beach, Visakhapatnam. Reported stranding of this species from coast of Andhra Pradesh is rare

Emerging organic contaminants in the river Ganga and key tributaries in the middle Gangetic Plain, India:Characterization, distribution & controls

The presence and distribution of emerging organic contaminants (EOCs) in freshwater environments is a key issue in India and globally, particularly due to ecotoxicological and potential antimicrobial resistance concerns. Here we have investigated the composition and spatial distribution of EOCs in surface water along a ∼500 km segment of the iconic River Ganges (Ganga) and key tributaries in the middle Gangetic Plain of Northern India. Using a broad screening approach, in 11 surface water samples, we identified 51 EOCs, comprising of pharmaceuticals, agrochemicals, lifestyle and industrial chemicals. Whilst the majority of EOCs detected were a mixture of pharmaceuticals and agrochemicals, lifestyle chemicals (and particularly sucralose) occurred at the highest concentrations. Ten of the EOCs detected are priority compounds (e.g. sulfamethoxazole, diuron, atrazine, chlorpyrifos, perfluorooctane sulfonate (PFOS), perfluorobutane sulfonate, thiamethoxam, imidacloprid, clothianidin and diclofenac). In almost 50% of water samples, sulfamethoxazole concentrations exceeded predicted no-effect concentrations (PNECs) for ecological toxicity. A significant downstream reduction in EOCs was observed along the River Ganga between Varanasi (Uttar Pradesh) and Begusarai (Bihar), likely reflecting dilution effects associated with three major tributaries, all with considerably lower EOC concentrations than the main Ganga channel. Sorption and/or redox controls were observed for some compounds (e.g. clopidol), as well as a relatively high degree of mixing of EOCs within the river. We discuss the environmental relevance of the persistence of several parent compounds (notably atrazine, carbamazepine, metribuzin and fipronil) and associated transformation products. Associations between EOCs and other hydrochemical parameters including excitation emission matrix (EEM) fluorescence indicated positive, significant, and compound-specific correlations between EOCs and tryptophan-, fulvic- and humic-like fluorescence. This study expands the baseline characterization of EOCs in Indian surface water and contributes to an improved understanding of the potential sources and controls on EOC distribution in the River Ganga and other large river systems

In-orbit Performance of UVIT on ASTROSAT

We present the in-orbit performance and the first results from the ultra-violet Imaging telescope (UVIT) on ASTROSAT. UVIT consists of two identical 38cm coaligned telescopes, one for the FUV channel (130-180nm) and the other for the NUV (200-300nm) and VIS (320-550nm) channels, with a field of view of 28 $arcmin$. The FUV and the NUV detectors are operated in the high gain photon counting mode whereas the VIS detector is operated in the low gain integration mode. The FUV and NUV channels have filters and gratings, whereas the VIS channel has filters. The ASTROSAT was launched on 28th September 2015. The performance verification of UVIT was carried out after the opening of the UVIT doors on 30th November 2015, till the end of March 2016 within the allotted time of 50 days for calibration. All the on-board systems were found to be working satisfactorily. During the PV phase, the UVIT observed several calibration sources to characterise the instrument and a few objects to demonstrate the capability of the UVIT. The resolution of the UVIT was found to be about 1.4 - 1.7 $arcsec$ in the FUV and NUV. The sensitivity in various filters were calibrated using standard stars (white dwarfs), to estimate the zero-point magnitudes as well as the flux conversion factor. The gratings were also calibrated to estimate their resolution as well as effective area. The sensitivity of the filters were found to be reduced up to 15\% with respect to the ground calibrations. The sensitivity variation is monitored on a monthly basis. UVIT is all set to roll out science results with its imaging capability with good resolution and large field of view, capability to sample the UV spectral region using different filters and capability to perform variability studies in the UV.Comment: 10 pages, To appear in SPIE conference proceedings, SPIE conference paper, 201

Physics Potential of the ICAL detector at the India-based Neutrino Observatory (INO)

The upcoming 50 kt magnetized iron calorimeter (ICAL) detector at the India-based Neutrino Observatory (INO) is designed to study the atmospheric neutrinos and antineutrinos separately over a wide range of energies and path lengths. The primary focus of this experiment is to explore the Earth matter effects by observing the energy and zenith angle dependence of the atmospheric neutrinos in the multi-GeV range. This study will be crucial to address some of the outstanding issues in neutrino oscillation physics, including the fundamental issue of neutrino mass hierarchy. In this document, we present the physics potential of the detector as obtained from realistic detector simulations. We describe the simulation framework, the neutrino interactions in the detector, and the expected response of the detector to particles traversing it. The ICAL detector can determine the energy and direction of the muons to a high precision, and in addition, its sensitivity to multi-GeV hadrons increases its physics reach substantially. Its charge identification capability, and hence its ability to distinguish neutrinos from antineutrinos, makes it an efficient detector for determining the neutrino mass hierarchy. In this report, we outline the analyses carried out for the determination of neutrino mass hierarchy and precision measurements of atmospheric neutrino mixing parameters at ICAL, and give the expected physics reach of the detector with 10 years of runtime. We also explore the potential of ICAL for probing new physics scenarios like CPT violation and the presence of magnetic monopoles.Comment: 139 pages, Physics White Paper of the ICAL (INO) Collaboration, Contents identical with the version published in Pramana - J. Physic