Comparative pharmaceutical and analytical study of Kasisadi Ghrita prepared by two different methods

Introduction: Sneha Kalpana are the dosage forms which can be used both internally as well as externally. Generally, Sneha Kalpana is prepared by using Agni as source of heating. However, Kasisadi Ghrita is an exception where the sunlight is used as source of heating. This unusual method of preparation looks attractive because of natural heat (sunlight) that is required in the preparation and the yield that may be obtained. The Sneha is heated with volatile drugs in Surya Paka for a specific time so that less heat allows them to leave their active principles in Sneha. The difference between Bhanupaka and Agnipaka is also an area of interest, on this formulation as far as its manufacturing is considered. Kasisadi Ghrita is a herbo-mineral formulation indicated for various skin diseases. Materials and Methods: Kasisadi Ghrita were prepared by classical method of Bhanupaka (KGB) and usual method of Agnipaka (KGA). Both KGB and KGA were analyzed as per the standard protocol. Discussion and Conclusion: Preparation of Kasisadi Ghrita by Agnipaka method is easy as it consumes less time. There were no pharmaceutical constraints in preparation of both samples. Tamra Paatra helps to retain more heat than other vessels during Bhanupaka. The results of the pharmaceutical and analytical study can be considered as the preliminary standards for the preparation of Kasisadi Ghrita