Effect of L-glutamine on electrocardiographic, hemodynamic, Left ventricular function parameters and heart antioxidant enzymes in STZ-nicotinamide induced cardiomyopathy in rat.

<p><b>Foot note:</b> Results are represented as mean ± SEM, (n = 6). Data was analyzed by one way ANOVA followed by <i>post hoc</i> Tukey's test, ^*<i>p</i><0.05, ^**<i>p</i><0.01, ^***<i>p</i><0.001 and ns –non-significant compared with diabetic control group, ^#<i>p</i><0.05, ^##<i>p</i><0.01, 442 ^###<i>p</i><0.001 and ns – non-significant when compared with control non-diabetic group. ^$<i>p</i><0.05, ^$$<i>p</i><0.001 compared with L-glutamine (500 mg/kg).</p

Histopathology of rat heart by hematoxyline and Eosin staining.

<p>NM =  normal myocardium, CE =  cytoplasmic eosinophilia, IN  =  mycardial inflammation, CV =  cytoplasmic vacuolization. (A) Non-diabetic control, (B) Diabetic control group, (C) L-glutamine (500 mg/kg) and (D) L-glutamine (1000 mg/kg).</p

Effect on electrocardiographic parameters.

<p>(A) Non-diabetic control, (B) Diabetic control group, (C) L-glutamine (500 mg/kg) and (D) L-glutamine (1000 mg/kg).</p