302 research outputs found

    Origin of second-harmonic generation in the incommensurate phase of K2SeO4

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    We show that a ferroelectric phase transition takes place in the incommensurate phase of the K2SeO4 crystal. The ferroelectric character of the IC phase explains the second-harmonic generation observed in the corresponding temperature range.Comment: 5 pages, 1 figur

    Constitutional-Legal and Political Responsibility of Political Parties in the Russian Federation to Electors

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    Analysis of the legal and political responsibility of officials of a democratically elected state to their constituents. The subjects of the above responsibility may be elected officials of the legislative (representative) bodies of state power. The constitutional status of elected persons exercising public authority on behalf of individuals suggests the possibility of terminating their powers as sanctions only on the basis of the rules of law enshrined in the relevant acts and establishing clear reasons and procedures for liability. The current legislation of the Russian Federation provides for various types of constitutional and legal sanctions

    Electronic educational resources in learning and fixing practical skills histology in the study in medical university

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    This article analyzes the first Russian experience in the development and application in teaching medical students a multimedia electronic educational resources in the Department of Histology. It is shown the need to introduce into the educational process of students new learning opportunities that enable professionals to form a new type of thinking, and owns the modern information technologies.Π‘Ρ‚Π°Ρ‚ΡŒΡ посвящСна Π°Π½Π°Π»ΠΈΠ·Ρƒ ΠΏΠ΅Ρ€Π²ΠΎΠ³ΠΎ Π² России ΠΎΠΏΡ‹Ρ‚Π° Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ ΠΈ примСнСния Π² ΠΎΠ±ΡƒΡ‡Π΅Π½ΠΈΠΈ студСнтов мСдицинских Π²ΡƒΠ·ΠΎΠ² ΠΌΡƒΠ»ΡŒΡ‚ΠΈΠΌΠ΅Π΄ΠΈΠΉΠ½ΠΎΠ³ΠΎ элСктронного ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ рСсурса Π½Π° ΠΊΠ°Ρ„Π΅Π΄Ρ€Π΅ гистологии. Показана Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ внСдрСния Π² ΡƒΡ‡Π΅Π±Π½Ρ‹ΠΉ процСсс Π½ΠΎΠ²Ρ‹Ρ… возмоТностСй обучСния студСнтов, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‰ΠΈΡ… Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ спСциалистов с Π½ΠΎΠ²Ρ‹ΠΌ Ρ‚ΠΈΠΏΠΎΠΌ ΠΌΡ‹ΡˆΠ»Π΅Π½ΠΈΡ ΠΈ Π²Π»Π°Π΄Π΅ΡŽΡ‰Π΅Π³ΠΎ соврСмСнными ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹ΠΌΠΈ тСхнологиями

    РаспространСнный аппСндикулярный ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚: лапароскопичСский ΠΈΠ»ΠΈ ΠΎΡ‚ΠΊΡ€Ρ‹Ρ‚Ρ‹ΠΉ доступ β€” критичСский Π°Π½Π°Π»ΠΈΠ·

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    The perforative acute appendicitis with the development of diffuse peritonitis increases the incidence of postoperative complications to 47%, and mortality to 3%. Mortality in the case of the development of diffuse purulent peritonitis makes 4.5-58%, and it can exceed 70% in severe forms of diffuse peritonitis with the development of infectious-toxic shock and multiple organ failure. National Clinical Guidelines for acute appendicitis with diffuse peritonitis allow for appendectomy from both the median and laparoscopic access in the absence of general contraindications to the creation of pneumoperitoneum. However, despite the proven advantages of laparoscopic appendectomy, there are opponents of its use in diffuse forms of appendicular peritonitis. An increased number of postoperative abscesses with a minimally invasive approach has been reported in literature; however, recent randomized studies refute this fact. There is also evidence that the laparoscopic method for appendicular peritonitis often leads to a lengthening of the operation time and higher operating costs, but at the same time there is a decrease in postoperative pain syndrome, a reduction in the length of inpatient treatment and early social and labor rehabilitation, which leads to an overall decrease in hospital costs. Thus, to date, there is no generally accepted opinion about the advisability of laparoscopic access for appendicular peritonitis. At the moment, the presence of diffuse peritonitis is the most common intraoperative reason for refusing a minimally invasive surgical treatment. However, there is a tendency to trying to standardize indications and contraindications, which was the objective of our literature review.ΠžΡΡ‚Ρ€Ρ‹ΠΉ Π°ΠΏΠΏΠ΅Π½Π΄ΠΈΡ†ΠΈΡ‚ являСтся Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ распространСнным острым хирургичСским Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠ΅ΠΌ ΠΈ, нСсмотря Π½Π° Ρ‚ΠΎ Ρ‡Ρ‚ΠΎ имССтся Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ сокращСниС Π΅Π³ΠΎ Π΄ΠΎΠ»ΠΈ Π² ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅ Π²Ρ€Π°Ρ‡Π°-Ρ…ΠΈΡ€ΡƒΡ€Π³Π° (40,3% β€” 2000, 24,8% β€” 2019), ΠΎΠ½ всС Ρ€Π°Π²Π½ΠΎ Π·Π°Π½ΠΈΠΌΠ°Π΅Ρ‚ ΠΏΠ΅Ρ€Π²ΠΎΠ΅ мСсто ΠΏΠΎ встрСчаСмости ΠΈ ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠΉ активности.ΠŸΠ΅Ρ€Ρ„ΠΎΡ€Π°Ρ‚ΠΈΠ²Π½Π°Ρ Ρ„ΠΎΡ€ΠΌΠ° острого Π°ΠΏΠΏΠ΅Π½Π΄ΠΈΡ†ΠΈΡ‚Π° с Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ΠΌ распространСнного ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π° ΡƒΠ²Π΅Π»ΠΈΡ‡ΠΈΠ²Π°Π΅Ρ‚ частоту послСопСрационных ослоТнСний Π΄ΠΎ 47%, Π° Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ β€” Π΄ΠΎ 3%. Π›Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π² случаС развития Ρ€Π°Π·Π»ΠΈΡ‚ΠΎΠ³ΠΎ Π³Π½ΠΎΠΉΠ½ΠΎΠ³ΠΎ ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π° составляСт 4,5–58%, Π° ΠΏΡ€ΠΈ тяТСлых Ρ„ΠΎΡ€ΠΌΠ°Ρ… распространСнного ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π° с Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ΠΌ ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΎΠ½Π½ΠΎ-токсичСского шока ΠΈ ΠΏΠΎΠ»ΠΈΠΎΡ€Π³Π°Π½Π½ΠΎΠΉ нСдостаточности ΠΌΠΎΠΆΠ΅Ρ‚ ΠΏΡ€Π΅Π²Ρ‹ΡˆΠ°Ρ‚ΡŒ 70%.ΠΠ°Ρ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹Π΅ клиничСскиС Ρ€Π΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°Ρ†ΠΈΠΈ ΠΏΡ€ΠΈ остром Π°ΠΏΠΏΠ΅Π½Π΄ΠΈΡ†ΠΈΡ‚Π΅ с распространСнным ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚ΠΎΠΌ Π΄ΠΎΠΏΡƒΡΠΊΠ°ΡŽΡ‚ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΈΠ΅ аппСндэктомии ΠΊΠ°ΠΊ ΠΈΠ· срСдинного, Ρ‚Π°ΠΊ ΠΈ ΠΈΠ· лапароскопичСского доступа ΠΏΡ€ΠΈ отсутствии ΠΎΠ±Ρ‰ΠΈΡ… ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ ΠΊ созданию ΠΏΠ½Π΅Π²ΠΌΠΎΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½Π΅ΡƒΠΌΠ°. Однако нСсмотря Π½Π° Π΄ΠΎΠΊΠ°Π·Π°Π½Π½Ρ‹Π΅ прСимущСства лапароскопичСской аппСндэктомии, ΠΈΠΌΠ΅ΡŽΡ‚ΡΡ ΠΏΡ€ΠΎΡ‚ΠΈΠ²Π½ΠΈΠΊΠΈ Π΅Π΅ использования ΠΏΡ€ΠΈ распространСнных Ρ„ΠΎΡ€ΠΌΠ°Ρ… аппСндикулярного ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π°.Π’ Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Π΅ ΠΎΡ‚ΠΌΠ΅Ρ‡Π΅Π½ΠΎ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ количСства послСопСрационных абсцСссов ΠΏΡ€ΠΈ минимально ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΠΎΠΌ доступС, ΠΎΠ΄Π½Π°ΠΊΠΎ послСдниС Ρ€Π°Π½Π΄Ρ€ΠΎΠΌΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Π΅ исслСдования ΠΎΠΏΡ€ΠΎΠ²Π΅Ρ€Π³Π°ΡŽΡ‚ Π΄Π°Π½Π½Ρ‹ΠΉ Ρ„Π°ΠΊΡ‚. Π’Π°ΠΊΠΆΠ΅ ΠΈΠΌΠ΅ΡŽΡ‚ΡΡ Π΄Π°Π½Π½Ρ‹Π΅, Ρ‡Ρ‚ΠΎ лапароскопичСский ΠΌΠ΅Ρ‚ΠΎΠ΄ ΠΏΡ€ΠΈ аппСндикулярном ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π΅ часто ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ ΡƒΠ΄Π»ΠΈΠ½Π΅Π½ΠΈΡŽ Π²Ρ€Π΅ΠΌΠ΅Π½ΠΈ ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΈ ΠΈ Π±ΠΎΠ»Π΅Π΅ высоким ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½Ρ‹ΠΌ Π·Π°Ρ‚Ρ€Π°Ρ‚Π°ΠΌ, Π½ΠΎ ΠΏΡ€ΠΈ этом происходит ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ Π±ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ послСопСрационного синдрома, сокращСниС сроков стационарного лСчСния ΠΈ ранняя ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎ-трудовая рСабилитация, Ρ‡Ρ‚ΠΎ ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ ΠΎΠ±Ρ‰Π΅ΠΌΡƒ сниТСнию расходов Π±ΠΎΠ»ΡŒΠ½ΠΈΡ†Ρ‹.Π’Π°ΠΊΠΈΠΌ ΠΎΠ±Ρ€Π°Π·ΠΎΠΌ, Π½Π° сСгодняшний дСнь Π½Π΅Ρ‚ общСпринятого мнСния ΠΎ цСлСсообразности лапаро­скопичСского доступа ΠΏΡ€ΠΈ аппСндикулярном ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π΅. На Π΄Π°Π½Π½Ρ‹ΠΉ ΠΌΠΎΠΌΠ΅Π½Ρ‚ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ частая интраопСрационная ΠΏΡ€ΠΈΡ‡ΠΈΠ½Π° ΠΎΡ‚ΠΊΠ°Π·Π° ΠΎΡ‚ минимально ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° хирургичСского лСчСния β€” Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ распространСнного ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π°. Однако прослСТиваСтся тСндСнция ΠΊ ΠΏΠΎΠΏΡ‹Ρ‚ΠΊΠ΅ ΡΡ‚Π°Π½Π΄Π°Ρ€Ρ‚ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ показания ΠΈ противопоказания, Ρ‡Ρ‚ΠΎ ΠΈ явилось Ρ†Π΅Π»ΡŒΡŽ нашСго Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Π½ΠΎΠ³ΠΎ ΠΎΠ±Π·ΠΎΡ€Π°

    Measurement of Dielectric Suppression of Bremsstrahlung

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    In 1953, Ter-Mikaelian predicted that the bremsstrahlung of low energy photons in a medium is suppressed because of interactions between the produced photon and the electrons in the medium. This suppression occurs because the emission takes place over on a long distance scale, allowing for destructive interference between different instantaneous photon emission amplitudes. We present here measurements of bremsstrahlung cross sections of 200 keV to 20 MeV photons produced by 8 and 25 GeV electrons in carbon and gold targets. Our data shows that dielectric suppression occurs at the predicted level, reducing the cross section up to 75 percent in our data.Comment: 11 pages, format is postscript file, gzip-ed, uuencode-e

    Anodal Block in Evaluation of Nerve Conduction Changes in Anesthetized Rats: Preclinical Non-Randomized Experimental Study

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    Background. There is currently no gold standard for functional assessment of nerve regeneration. Different researchers use various methods to assess the functionality of the regenerated nerve directly and indirectly. Indirect methods have the advantage of being minimally invasive, and the benefit of direct methods is recording the signal directly in the nerve.Objectives. To identify significant parameters of neurogram changes in the sciatic nerve in an anaesthetized rat when the anode block is applied and to evaluate neurography as a method for functional assessment of nerve regeneration.Methods. A series of experiments was performed on 10 anaesthetized rats. A DC anode was placed on the exposed sciatic nerve, more proximal and more distal to the recording electrodes, and a common cathode in the form of a needle was introduced into one of the forelimbs. Needle nichrome electrodes were introduced into the nerve using a manipulator. An original neurogram and a neurogram against anode activation were recorded by closing the DC circuit of different voltages to block the afferent signal, efferent signal and afferent and efferent signals simultaneously.Results. When the anodal block of different voltages was applied to the afferent signal, efferent signal, and afferent and efferent signals simultaneously in all 10 experiments, the frequency-amplitude characteristics of the neurogram changed significantly as compared to the original neurogram. The amplitude of the neurogram increased considerably, while the frequency decreased, though not so dramatically. The changes in amplitude and frequency parameters were revealed to depend on the voltage value. In most cases, this relationship was directly proportional to the amplitude and inversely proportional to the frequency.Conclusion. Considering the nature of the dynamics of the neurogram when exposed to the anodal block, the most significant parameter of its change is the amplitude. Changes in nerve fibre composition during its regeneration after damage cause changes in afferent and efferent signals, which is likely to be displayed in the neurogram as compared to the initial state. Thus, the anodal block can be used as a model of nerve damage, and the analysis of the dynamics of neurogram parameters β€” as a method for functional assessment of nerve regeneration

    Bremsstrahlung Suppression due to the LPM and Dielectric Effects in a Variety of Materials

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    The cross section for bremsstrahlung from highly relativistic particles is suppressed due to interference caused by multiple scattering in dense media, and due to photon interactions with the electrons in all materials. We present here a detailed study of bremsstrahlung production of 200 keV to 500 MeV photons from 8 and 25 GeV electrons traversing a variety of target materials. For most targets, we observe the expected suppressions to a good accuracy. We observe that finite thickness effects are important for thin targets.Comment: 52 pages, 13 figures (incorporated in the revtex LaTeX file

    Comparison of the results of <sup>85</sup>Kr transport modeling with the ACURATE field experiment data

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    Β© 2017, Allerton Press, Inc.Currently the Nuclear Safety Institute of the Russian Academy of Sciences (NSI RAS) jointly with the Hydrometcenter of Russia is developing the system for forecasting the transfer of radio-active substances in the atmosphere in case of radiation accidents at Russian nuclear power plants. The operation of the system is based on the numerical hydrodynamic model which allows forecasting meteorological parameters and is coupled with the mesoscale dispersion model of the transfer ofradioactive substances in the atmosphere. The results are presented of 85Kr transport modeling under the conditions of the ACURATE experiment with three transport models: FLEXPART, HYSPLIT, and the model from the NOSTRADAMUS software package. It is demonstrated that all three Lagrangian models can give a qualitative description of concentration fields from the ACURATE experiment with the best value of the RANK metric (2.5) based on three statistics

    APLIKASI MANAJEMEN KEGIATAN UNTUK ORGANISASI NON PROFIT BERBASIS WEBSITE

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    Suatu organisasi memiliki berbagai program kerja, yang di dalamnya ada kepanitian khusus. Biasanya manajemen kegiatan yang berisi pengelolaan keuangan pada masing-masing organisasi dan lembaga dikepalai oleh bendahara. Pengelolaan keuangan tersebut menjadi sebuah kebutuhan, karena bendahara tersebut wajib selalu melaporkan pencatatan keuangan. Tentu akan menjadi tidak efektif jika melakukan pencatatan keuangan harus melakukannya secara manual. Di samping susah, pencatatan secara manual sangat beresiko seperti rusak dan hilangnya buku pencatatan. Ada lagi pencatatan dengan cara lain yaitu menggunakan software yang sudah ada seperti Microsoft Excel, namun hal tersebut masih kurang efisien dan kurang efektif sehingga diperlukan tools pencatatan yang lebih baik agar mencapai tujuan dan sasaran yang diinginkan. Subjek penelitian yang dibahas pada penelitian ini adalah aplikasi pengelolaan keuangan untuk organisasi non profit berbasis website. Langkah pengembangan aplikasi yaitu menggunakan waterfall model. Dari penelitian yang dilakukan menghasilkan sebuah website tentang ”aplikasi manajemen kegiatan untuk organisasi non profit berbasis website” yang dapat digunakan untuk melakukan manajemen kegiatan bagi organisasi non profit sehingga pekerjaan seorang bendahara menjadi mudah dan efektif.Keywords: Manajemen Kegiatan, Nonprofit Online, Organisasi Non Profit

    Some of the expression patterns of immunohistochemical markers on cells of breast carcinoma

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    In breast cancer, the level of topoisomerase lla (TOP lla) expression can have independent predictive importance due to effective antibiotic treatment with anthracycline, which acts against this protein. 578 cases of infiltrative breast carcinoma were studied. The expression of TOP lla, Ki-67, Her2-neu, ER, PR was studied by immunohistochemical method. Expression of TOP lla was evaluated with use of the scale, developed by L. Usha (overexpression > 35%). Overexpression of TOP lla was found in 14 % of breast carcinomas. The strong positive correlation was found between increase of Ki-67 expression and TOP 2a expression. We did not find any significant dependence of T0P2a expression from Her-2/neu, ER and PR expression.ΠŸΡ€ΠΈ Ρ€Π°ΠΊΠ΅ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ экспрСссии Ρ‚ΠΎΠΏΠΎΠΈΠ·ΠΎΠΌΠ΅Ρ€Π°Π·Ρ‹ На (ВОР Па) ΠΌΠΎΠΆΠ΅Ρ‚ ΠΈΠΌΠ΅Ρ‚ΡŒ ΡΠ°ΠΌΠΎΡΡ‚ΠΎΡΡ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ ΠΏΡ€Π΅Π΄ΠΈΠΊΡ‚ΠΈΠ²Π½ΠΎΠ΅ Π·Π½Π°Ρ‡Π΅Π½ΠΈΠ΅ Π² связи с эффСктивной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠ΅ΠΉ ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ Π°Π½Ρ‚ΠΈΠ±ΠΈΠΎΡ‚ΠΈΠΊΠ°ΠΌ Π³Ρ€ΡƒΠΏΠΏΡ‹ Π°Π½Ρ‚Ρ€Π°Ρ†ΠΈΠΊΠ»ΠΈΠ½ΠΎΠ², Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½Ρ‹Ρ… Π½Π° ΠΈΠ½Π³ΠΈΠ±ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ Π΄Π°Π½Π½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ°. Π˜ΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Ρ‹ 578 случая ΠΈΠ½Ρ„ΠΈΠ»ΡŒΡ‚Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠΉ ΠΊΠ°Ρ€Ρ†ΠΈΠ½ΠΎΠΌΡ‹ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ Π½Π° ΡΠΊΡΠΏΡ€Π΅ΡΡΠΈΡŽ ВОР Па, Ki-67, HER-2/neu, ER, PR иммуногистохимичСским ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ. ЭкспрСссия Ρ‚ΠΎΠΏΠΎΠΈΠ·ΠΎΠΌΠ΅Ρ€Π°Π·Ρ‹ Па ΠΎΡ†Π΅Π½ΠΈΠ²Π°Π»Π°ΡΡŒ ΠΏΠΎ шкалС, ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½Π½ΠΎΠΉ L. Usha (гипСрэкспрСссия > 35%). ГипСрэкспрСссия ΠΏΠΎ Ρ‚ΠΎΠΏΠΎΠΈΠ·ΠΎΠΌΠ΅Ρ€Π°Π·Π΅ Па Π½Π°Π±Π»ΡŽΠ΄Π°Π΅Ρ‚ΡΡ Π² 14% ΠΎΠ±Ρ€Π°Π·Ρ†ΠΎΠ² ΠΊΠ°Ρ€Ρ†ΠΈΠ½ΠΎΠΌΡ‹ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹. ΠžΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Π° ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½Π°Ρ сильная Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡ‚ΡŒ ΠΌΠ΅ΠΆΠ΄Ρƒ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ΠΌ стСпСни экспрСссии Ki-67 ΠΈ ВОР Па. Π—Π°Π²ΠΈΡΠΈΠΌΠΎΡΡ‚ΡŒ уровня экспрСссии Ρ‚ΠΎΠΏΠΎΠΈΠ·ΠΎΠΌΠ΅Ρ€Π°Π·Ρ‹ На ΠΎΡ‚ экспрСссии НСг-2/ΠΏΠ΅ΠΈ, ER, PR Π½Π΅ ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Π°
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