3 research outputs found
Application of Baltic Pine (Pinus sylvestris) Needle Extract as a Gut Microbiota-Modulating Feed Supplement for Domestic Chickens (Gallus gallus)
Funding Information: This research was funded within the framework of the European Agricultural Fund for Rural Development (EAFRD) program, grant number 18-00-A01620-000042. Publisher Copyright: Ā© 2023 by the authors.The valorization of wood industry residues is very desirable from a circular economy perspective. Pine needle extracts are known for their health-promoting properties and therefore can be used as herbal remedies and nutritional supplements. Since the withdrawal of antibiotics as growth promoters in the European Union, natural feed additives that improve poultry health and production are needed. It was proposed that pine needle extract could be a good alternative to antibiotic usage at sub-therapeutic concentrations. The results relevant to our assumption could be obtained by using domestic chickens as an in vivo model for the evaluation of gut microbiota-altering properties of pine needle extract as an herbal supplement. We tested the antimicrobial effects of Baltic pine (Pinus sylvestris) needle extract. Then, we used chicken (Gallus gallus) that received feed supplemented with two different concentrations of the extract for 40 days to evaluate the changes in gut microbiota using 16S rRNA gene sequencing. This preliminary study demonstrated trends toward dose-dependent desirable changes in broiler microbiome, such as a reduction in the relative abundance of Campylobacter.publishersversionPeer reviewe
Prevalence and treatment of arterial hypertension in hospitalised patients with type 2 diabetes mellitus
ArteriÄlÄ hipertensija ir bieži sastopama pacientiem ar 2. tipa CD. PasaulÄ pÄc prognostiskiem datiem 2. tipa CD slimnieku skaits dubultosies lÄ«dz 2030. gadam, tas nozÄ«mÄ, ka palielinÄsies arÄ« 2. tipa CD radÄ«to komplikÄciju incidence, viena no kurÄm ir arteriÄlÄ hipertensija. Å Ä« komplikÄcija rada virkni procesu, kuri ietekmÄ pacienta darbaspÄjas, dzÄ«ves kvalitÄti un dzÄ«ves ilgumu.
PÄtÄ«juma mÄrÄ·is bija noskaidrot arteriÄlÄs hipertensijas izplatÄ«bu un ÄrstÄÅ”anas metodes 2. tipa CD slimniekiem; iegÅ«tos rezultÄtus salÄ«dzinÄt ar kontroles grupu, kurÄ tika iekļauti hospitalizÄtie cilvÄki vecumÄ pÄc 45 gadiem bez 2. tipa CD un citÄm endokrÄ«nÄm saslimÅ”anÄm. Tika salÄ«dzinÄti riska faktori: smÄÄ·ÄÅ”ana, stresa ietekme, alkohola lietoÅ”ana, arteriÄlÄ hipertensija un 2. tipa CD anamnÄze radiniekiem.
ArteriÄlÄ hipertensija tika konstatÄta 85,4% 2. tipa CD slimniekiem, tas ir par 54,7% biežÄk nekÄ respondentiem, kuriem nav 2. tipa CD. PaaugstinÄts asinsspiediens dažÄdÄs pakÄpÄs tika konstatÄts 87,9% sievieÅ”u un 70% vÄ«rieÅ”u, kuri slimo ar 2. tipa CD; savukÄrt respondentiem, kuri neslimo ar 2. tipa CD, sievieÅ”u starpÄ paaugstinÄts asinsspiediens tika konstatÄts 53,4% un vÄ«rieÅ”u - 59%.
Tas nozÄ«mÄ, ka arteriÄlÄ hipertensija ir vairÄk izplatÄ«ta starp 2. tipa CD slimniekiem. Å ajÄ grupÄ ir biežÄk sastopamas augstÄkas arteriÄlÄs hipertensijas pakÄpes nekÄ kontroles grupÄ. AbÄs grupÄs respondentus vienÄdi ietekmÄ riska faktori - smÄÄ·ÄÅ”ana, palielinÄts ĶMI, diÄtas neievÄroÅ”ana. Daudziem respondentiem trÅ«kst motivÄcijas sekot lÄ«dzi savam arteriÄlajam asinsspiedienam; respondenti nepievÄrÅ” uzmanÄ«bu tam, kÄdu antihipertensÄ«vo terapiju viÅi saÅem, kÄ arÄ« nozÄ«mÄtos medikamentus lieto neregulÄri.Arterial hypertension is common for patients with type 2 diabetes. Prognostic data for worldwide shows that number of patients with type 2 diabetes will double by 2030, this means that the increase in type 2 diabetes incidence, also will increase the type 2 diabetes complications incidence one of which is arterial hypertension. This complication run series of processes, that effect patients ability to work, quality of life and survival.
The aim of the study was to determine the prevalence and treatment methods of arterial hypertension for type 2 diabetes patients and to compare the results with the control group, which included people aged over 45 years, hospitalized without type 2 diabetes and other endocrinological diseases. The aim was also to compare risk factors such as: smoking, exposure to stress, alcohol intake, arterial hypertension and type 2 diabetes in the family.
Arterial hypertension was found for 85.4% of patients who have type 2 diabetes, which is 54.7% more likely than respondents who do not have type 2 diabetes. Increased varying degrees of blood pressure was found for 87.9% women and 70% men suffering from type 2 diabetes, while respondents who suffer from type 2 diabetes among women high blood pressure was found in 53.4% cases and for men - in 59% cases.
This means that arterial hypertension is more common among patients with type 2 diabetes, this group is more common in higher grade arterial hypertension than in the control group. Both groups of respondents were equally affected by risk factors such as smoking, higher BMI. Many respondents are not motivated to follow up the level of blood pressure, they do not pay attention what antihypertensive medication they receive, as well they use antihypertensive therapies occasionally
Application of Baltic Pine (<i>Pinus sylvestris</i>) Needle Extract as a Gut Microbiota-Modulating Feed Supplement for Domestic Chickens (<i>Gallus gallus</i>)
The valorization of wood industry residues is very desirable from a circular economy perspective. Pine needle extracts are known for their health-promoting properties and therefore can be used as herbal remedies and nutritional supplements. Since the withdrawal of antibiotics as growth promoters in the European Union, natural feed additives that improve poultry health and production are needed. It was proposed that pine needle extract could be a good alternative to antibiotic usage at sub-therapeutic concentrations. The results relevant to our assumption could be obtained by using domestic chickens as an in vivo model for the evaluation of gut microbiota-altering properties of pine needle extract as an herbal supplement. We tested the antimicrobial effects of Baltic pine (Pinus sylvestris) needle extract. Then, we used chicken (Gallus gallus) that received feed supplemented with two different concentrations of the extract for 40 days to evaluate the changes in gut microbiota using 16S rRNA gene sequencing. This preliminary study demonstrated trends toward dose-dependent desirable changes in broiler microbiome, such as a reduction in the relative abundance of Campylobacter