Population genetic structure of Helixpomatia L. (Mollusca, Pulmonata) from the southeastern and eastern parts of the range

On the basis of the analysis of genetic variation detectable by ISSR-PCR, the state of the gene pools of 14 populations of Roman snail Helix pomatia L. in the conditions of urbanized landscapes of the southeastern and eastern parts of the current range was examined. According to the data obtained, the majority of the studied populations of this mollusk are in satisfactory conditio

Estimation of the genetic structure of Helix pomatia L. populations (Mollusca, Pulmonata) by capillary electrophoresis of ISSR DNA fragments

Using the capillary electrophoresis of ISSR DNA fragments, the genetic structure of the adventitious populations of Helix pomatia L. (Mollusca, Pulmonata) inhabiting the territory of Eastern Europe was studie

Population genetic structure of Helixpomatia L. (Mollusca, Pulmonata) from the southeastern and eastern parts of the range

On the basis of the analysis of genetic variation detectable by ISSR-PCR, the state of the gene pools of 14 populations of Roman snail Helix pomatia L. in the conditions of urbanized landscapes of the southeastern and eastern parts of the current range was examined. According to the data obtained, the majority of the studied populations of this mollusk are in satisfactory conditio

The assessment of the genetic structure of bush snail (fruticicola fruticum) populations based on the nonspecific esterases loci

Using the polymorphic esterases loci, the genetic structure of the gastropod mollusk Fruticicola (Bradybaena) fruticum Mull., most of which lives in the south of the Central Russian Upland, was studied. For comparison, the samples were taken from the Romania, the North Caucasus, the Ural and the Vyatka regions. A total of the 1668 individuals were investigated. Of the 28 stu died populations in 11 (39.3%), there was significant shortage of the heterozygotes. The level of the expected heterozygosity fluctuated in the range He = 0.116-0.454. Using the non-parametric statistics (Chao1-bc method and 1st order jackknife method), the populations with potentially high and low diversity of the multilocus genotypes were identified. The indicators of the genetic disunity between populations averaged Φst = 0.276, Fst = 0.292. The principal component analysis and the Mantel correlation criterion RM = -0.007 showed the absence of a reliable relationship between the geographical and genetic distance between populations, which indicates a violation of the isolation model by distance and confirms the thesis put forward by us that the urbanized forest-steppe landscape disrupts the natural migration processes, leads to the strong isolation and the genetic drift in the snail populations. At the same time, the phenomenon of increasing the degree of division of the populations against the background of reduced the allelic diversity, noted by us in many groups of bush snails, can be regarded as a shift in genetic equilibrium towards an increase in the interpopupulation diversity (according to the Wright model). The revealed absence of the effect of isolation by distance can be a consequence of the action of the stabilizing natural selection. The assumption of the dependence of the esterase alleles frequencies in the bush snail populations on the genetic (biochemical) characteristics of the food objects was proposed. The effective size, calculated using the Slatkin formula turned out to be comparable with the background, adventive and relict species of the terrestrial mollusks living in the study area (Ne = 2.2-7.6). © 2019 Eco-Vector LLC. All rights reserved

Estimation of the genetic structure of Helix pomatia L. populations (Mollusca, Pulmonata) by capillary electrophoresis of ISSR DNA fragments

Using the capillary electrophoresis of ISSR DNA fragments, the genetic structure of the adventitious populations of Helix pomatia L. (Mollusca, Pulmonata) inhabiting the territory of Eastern Europe was studie

The ESC ACCA EAPCI EORP acute coronary syndrome ST-elevation myocardial infarction registry

Aims: The Acute Cardiac Care Association (ACCA)-European Association of Percutaneous Coronary Intervention (EAPCI) Registry on ST-elevation myocardial infarction (STEMI) of the EurObservational programme (EORP) of the European Society of Cardiology (ESC) registry aimed to determine the current state of the use of reperfusion therapy in ESC member and ESC affiliated countries and the adherence to ESC STEMI guidelines in patients with STEMI. Methods and results: Between 1 January 2015 and 31 March 2018, a total of 11 462 patients admitted with an initial diagnosis of STEMI according to the 2012 ESC STEMI guidelines were enrolled. Individual patient data were collected across 196 centres and 29 countries. Among the centres, there were 136 percutaneous coronary intervention centres and 91 with cardiac surgery on-site. The majority of centres (129/196) were part of a STEMI network. The main objective of this study was to describe the demographic, clinical, and angiographic characteristics of patients with STEMI. Other objectives include to assess management patterns and in particular the current use of reperfusion therapies and to evaluate how recommendations of most recent STEMI European guidelines regarding reperfusion therapies and adjunctive pharmacological and non-pharmacological treatments are adopted in clinical practice and how their application can impact on patients' outcomes. Patients will be followed for 1 year after admission. Conclusion: The ESC ACCA-EAPCI EORP ACS STEMI registry is an international registry of care and outcomes of patients hospitalized with STEMI. It will provide insights into the contemporary patient profile, management patterns, and 1-year outcome of patients with STEMI

Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: The ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology

Aims: The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). Methods and results: Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset <24 h in 196 centres across 29 countries. A total of 11 462 patients were enrolled, for whom primary percutaneous coronary intervention (PCI) (total cohort frequency: 72.2%, country frequency range 0-100%), fibrinolysis (18.8%; 0-100%), and no reperfusion therapy (9.0%; 0-75%) were performed. Corresponding in-hospital mortality rates from any cause were 3.1%, 4.4%, and 14.1% and overall mortality was 4.4% (country range 2.5-5.9%). Achievement of quality indicators for reperfusion was reported for 92.7% (region range 84.8-97.5%) for the performance of reperfusion therapy of all patients with STEMI <12 h and 54.4% (region range 37.1-70.1%) for timely reperfusion. Conclusions: The use of reperfusion therapy for STEMI in the ESC member and affiliated countries was high. Primary PCI was the most frequently used treatment and associated total in-hospital mortality was below 5%. However, there was geographic variation in the use of primary PCI, which was associated with differences in in-hospital mortality