Symptoms of anxiety and depression in type 2 diabetes: Associations with clinical diabetes measures and self-management outcomes in the norwegian HUNT study

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.OBJECTIVE: To determine if symptoms of depression and anxiety are differentially associated with clinical diabetes measures and self-management behaviours in individuals with Type 2 diabetes, and whether these associations vary by patient sex. RESEARCH DESIGN AND METHODS: A cross-sectional analysis using data from 2035 adults with Type 2 diabetes in the Nord-Trøndelag Health Study. Multivariate logistic regression was used to explore associations between symptoms of depression and anxiety and waist girth, HDL cholesterol, systolic blood pressure, triglycerides, c-reactive protein, glycemic control, diet adherence, exercise, glucose monitoring, foot checks for ulcers, and the subjective patient experience. Analyses were stratified by sex. RESULTS: Depression was associated with a lower likelihood of avoiding saturated fats (OR=0.20 [95% CI: 0.06, 0.68]) and increased odds of physical inactivity (OR=1.69 [95% CI: 1.37, 2.72]). Anxiety was associated with increased odds of eating vegetables (OR=1.66 [95% CI: 1.02, 2.73]), and an over two-fold increase of feeling that having diabetes is difficult. In women, anxiety was associated with elevated c-reactive protein levels (OR=1.57 [95% CI: 1.05, 2.34]). In men, depressive symptoms were associated with elevated HbA1c (OR=5.00 [95% CI: 1.15, 8.23). CONCLUSIONS: Symptoms of depression and anxiety were differentially associated with some key diabetes-related measures. Our results suggest sex-specific differences with respect to two important clinical outcomes (i.e., anxiety and CRP in women and depression and glycemic control in men). These findings should alert practitioners to the importance of detection and management of psychological symptoms in individuals with Type 2 diabetes.Revisión por pare

Diabetes Mellitus tipo 2 y Síntomas de ansiedad: Un estudio transversal en Perú

Objective: To determine the association between diabetes mellitus type 2 and anxiety symptoms using a population-based study from the semi urban population of Tumbes, Peru. Research design and methods: The present study was an observational, analytical cross-sectional one. Data from a population-based study conducted in Tumbes, Peru between 2016 and 2017 was analyzed. The variables studied were T2DM, defined using fasting glucose and anxiety symptoms, using the Goldberg scale. Results: Data from 1609 individuals was analyzed, with mean age 48.16 (SD:10.61) and 810 women (50.3%), where a total of 161 were classified as having T2DM (10.0%; CI 95%: 8.5%-11.4%) and 675 individuals had anxiety symptoms (41.95%; CI 95%:39.5%-44.3%). A statistically significant association was found between DM2 and anxiety symptoms (p <0.001). Furthermore, those patients aware of their diagnosis of diabetes over 5 years had a 56% (95% CI: 25% - 96%) higher prevalence of anxiety symptoms compared to participants without DM2. Conclusion: An association was found between DM2 and anxiety symptoms; there being a higher prevalence of anxiety symptoms in participants previously aware of having DM2. Periodic monitoring of anxiety symptoms is recommended in these patients.Objetivo: Determinar si existe una asociación entre diabetes mellitus tipo 2 y síntomas de ansiedad usando un estudio de base poblacional en la zona de Tumbes, Perú. Material y Métodos: El presente estudio fue de tipo observacional, transversal analítico. Se analizaron los datos procedentes de un estudio realizado en Tumbes, Perú entre los años 2016 al 2017. Las variables de interés fueron diabetes mellitus tipo 2 como exposición; medido con glucosa en ayunas, y síntomas de ansiedad como variable resultado, evaluado usando la escala de Goldberg. Resultados: Se analizó 1609 individuos con edad media de 48,16 (DE:10,61) y 810 mujeres (50,3%); donde un total de 161 participantes padecían de DM2 (10,0%; IC 95%: 8,5%-11,4%) y 675 participantes (41,95%; IC95%:39,5%-44,3%) tenían síntomas de ansiedad. Se encontró una asociación estadísticamente significativa entre DM2 y síntomas de ansiedad (p<0,001); más aún, aquellos pacientes con diagnóstico de diabetes mayor a 5 años tenían 56% (IC 95%: 25% - 96%) mayor prevalencia de síntomas de ansiedad en comparación con los participantes sin DM2. Conclusión: Se encontró asociación entre DM2 y síntomas de ansiedad; habiendo mayor prevalencia de síntomas de ansiedad en los participantes previamente conscientes de padecer DM2. Se recomienda hacer un seguimiento periódico de los síntomas de ansiedad en estos pacientes.Tesi