Alts : An Adaptive Load Balanced Task Scheduling Approach for Cloud Computing

Abstract: According to the research, many task scheduling approaches have been proposed like GA, ACO, etc., which have improved the performance of the cloud data centers concerning various scheduling parameters. The task scheduling problem is NP-hard, as the key reason is the number of solutions/combinations grows exponentially with the problem size, e.g., the number of tasks and the number of computing resources. Thus, it is always challenging to have complete optimal scheduling of the user tasks. In this research, we proposed an adaptive load-balanced task scheduling (ALTS) approach for cloud computing. The proposed task scheduling algorithm maps all incoming tasks to the available VMs in a load-balanced way to reduce the makespan, maximize resource utilization, and adaptively minimize the SLA violation. The performance of the proposed task scheduling algorithm is evaluated and compared with the state-of-the-art task scheduling ACO, GA, and GAACO approaches concerning average resource utilization (ARUR), Makespan, and SLA violation. The proposed approach has revealed significant improvements concerning the makespan, SLA violation, and resource utilization against the compared approaches

Hierarchical plant extracts in silver nanoparticles preparation: Minuscular survey to achieve enhanced bioactivities

Extracts obtained from M. longifolia (Lamiaceae) and R. ellipticus (Rosaceae) were selected to utilize in the reduction and stabilization of silver nanoparticles (AgNPs) for achieving remarkable bioactivities. In brief, the cytotoxic potential of the as synthesize AgNPs was high at higher concentrations. In DPPH assay, maximum antioxidant potential was shown by AgNPs synthesized from M. longifolia. Meanwhile, Methanolic extracts exhibited more antioxidant potential than chloroform based extracts.Further, brine shrimp lethality assay was carried out to achieve 34.6 μg/mL & 25.65 μg/mL LD50 values against the NPs prepared from M. and R., respectively. In addition, antioxidant activities were carried by ABTS Radical cation assay where 38.6 μg/mL and 47 μg/mL IC50 values were obtained for the NPs obtained from M. longifolia and R. ellipticus, respectively. Reducing power assay (0.370–0.15 and 0.37–0.26 mean absorbance) and DPPH (% scavenging: 88.91–46.48 and 88.91–44.78) percentages were recorded for M. and R. synthesized AgNPs, respectively.In brief, M. longifolia functionalized particles performed better in comparison to R. ellipticus treated particles. In addition, the nano assembly dispersed in polar solvent demonstrated better results in comparison to non-polar solvents.In conclusion, the as synthesized AgNPs were better in bioactivities than crude extracts of the selected plants.In future, this work could be extended to isolating active components for the nanofabrication of biologically intelligent nanoparticles for pharmacological interest. In the proposed investigation, the purified bioactivities fractions would be highlighted for further consideration in various medical treatments

Anti-Snake Venom Properties of Medicinal Plants: A Comprehensive Systematic Review of Literature

Snakebite is one of the major health issues posing considerable morbidity and mortality. According to an estimate of World Health Organization (WHO) (World health organization, 2021) approximately 5 million people are bitten by several species of snakes resulting in up to 2.5 million envenomation cases annually. The mainstay of treatment for envenomation is intravenous administration of anti-snake venom. Although antivenom neutralizes the systemic effects but it does not relieve the symptoms such as venom-induced hemorrhage, necrosis and nephrotoxicity. Moreover, the use of antivenoms is associated with hypersensitivity reactions including urticaria, anaphylaxis, or serum sickness due to their heterologous property. Furthermore, stringent storage conditions and narrow specificity of antivenoms limit their use in both developed as well as developing countries. In this context, researchers have been searching for natural products and plant extracts to explore their antivenom activity along with anti-myotoxic, anti-hemorrhagic and anti-inflammatory properties. Plant remedies may prove to be an effective alternate for antivenom sera with less adverse events and better tolerability. To the best of our knowledge, this is the first comprehensive review of medicinal plants possessing anti-snake venom activities against certain species of snakes. The current review highlights the investigated plants with their phytochemical analysis to integrate the available information for future research and development of antivenom sera