Crime Script Sequencing: An optimal forensic combination for cold case analysis

Criminal cases go cold when investigative leads or forensic testing does not lead to a successful arrest. In these cases, investigators are often keen to use novel methods to derive fresh ideas or insights. Recently, academics from a range of fields, including Psychology, Criminology, and Forensic Sciences have developed a range of new methods and tests to assist with police investigations. The current paper outlines a novel approach to assisting with police cold case investigations: Crime Script Sequencing. The new method combines two leading temporal methods, Crime Script Analysis and Behaviour Sequence Analysis. A real-world cold case, the bombing of Canadian Pacific Airlines Fight 21, is presented and analysed using Crime Script Sequencing to offer readers a guide of how to use the method for other investigations. Impacts, insights, and potential future developments of the method are outlined

A confirmed case of toxic shock syndrome associated with the use of a menstrual cup

Menstrual cups have been reported to be an acceptable substitute for tampons. These flexible cups have also been reported to provide a sustainable solution to menstrual management, with modest cost savings and no significant health risk. The present article documents the first case of toxic shock syndrome associated with the use of a menstrual cup in a woman 37 years of age, using a menstrual cup for the first time. Toxic shock syndrome and the literature on menstrual cups is reviewed and a possible mechanism for the development of toxic shock syndrome in the patient is described

A confirmed case of toxic shock syndrome associated with the use of a menstrual cup

Menstrual cups have been reported to be an acceptable substitute for tampons. These flexible cups have also been reported to provide a sustainable solution to menstrual management, with modest cost savings and no significant health risk. The present article documents the first case of toxic shock syndrome associated with the use of a menstrual cup in a woman 37 years of age, using a menstrual cup for the first time. Toxic shock syndrome and the literature on menstrual cups is reviewed and a possible mechanism for the development of toxic shock syndrome in the patient is described

Behaviour Tracking: Using geospatial and behaviour sequence analysis to map crime

Crime is a complex phenomenon. To understand the commission of crime, researchers must map both the temporal and the spatial processes involved. The current research combines a temporal method of analysis, Behaviour Sequence Analysis, with geospatial mapping, to outline a new method of integrating temporal and spatial movements of criminals. To show how the new method can be applied, a burglary scenario was used, and the movements and behaviours of a criminal tracked around the property. Results showed that combining temporal and spatial analyses allows for a clearer account of the process of a crime scene. The current method has application to a large range of other crimes and terrorist movements, for instance between cities and movements within each city. Therefore, the current research provides the foundation framework for a novel method of spatio-temporal analyses of crime

Clinical characteristics, multiorgan dysfunction and outcomes of patients with COVID-19: a prospective case series

BACKGROUND: Characterizing the multiorgan manifestations and outcomes of patients hospitalized with COVID-19 will inform resource requirements to address the long-term burden of this disease. We conducted a descriptive analysis using prospectively collected data to describe the clinical characteristics and spectrum of organ dysfunction, and in-hospital and longer-term clinical outcomes of patients hospitalized with COVID-19 during the first wave of the pandemic at a Canadian centre. METHODS: We conducted a prospective case series involving adult patients (aged ≥ 18 yr) with COVID-19 admitted to 1 of 2 hospitals in London, Ontario, from Mar. 17 to June 18, 2020, during the first wave of the pandemic. We recorded patients\u27 baseline characteristics, physiologic parameters, measures of organ function and therapies administered during hospitalization among patients in the intensive care unit (ICU) and in non-ICU settings, and compared the characteristics of hospital survivors and nonsurvivors. Finally, we recorded follow-up thoracic computed tomography (CT) and echocardiographic findings after hospital discharge. RESULTS: We enrolled 100 consecutive patients (47 women) hospitalized with COVID-19, including 32 patients who received ICU care and 68 who received treatment in non-ICU settings. Respiratory sequelae were common: 23.0% received high-flow oxygen by nasal cannula, 9.0% received noninvasive ventilation, 24.0% received invasive mechanical ventilation and 2.0% received venovenous extracorporeal membrane oxygenation. Overall, 9.0% of patients had cerebrovascular events (3.0% ischemic stroke, 6.0% intracranial hemorrhage), and 6.0% had pulmonary embolism. After discharge, 11 of 19 patients had persistent abnormalities on CT thorax, and 6 of 15 had persistent cardiac dysfunction on echocardiography. INTERPRETATION: This study provides further evidence that COVID-19 is a multisystem disease involving neurologic, cardiac and thrombotic dysfunction, without evidence of hepatic dysfunction. Patients have persistent organ dysfunction after hospital discharge, underscoring the need for research on long-term outcomes of COVID-19 survivors

Glucolipotoxicity initiates pancreatic beta-cell death through TNFR5/CD40-mediated STAT1 and NF-kappa B activation

Funded by Diabetes UK, NovoNordisk UK Research Foundation, and St. Bartholomew’s & The Royal London Charitable Foundation grant awards

A behavior sequence analysis of victims’ accounts of stalking behaviors

Stalking is a complex issue involving multiple behaviors and interactions between the stalker and their target. Research has typically involved grouping risk behaviors related to stalking; however, the research question in the current research was to what extent a temporal method would allow investigators to map the dynamics of stalking. Behavior Sequence Analysis is a form of systems analysis that examines sequences of events over time, providing statistically significant results from complex real-world data. The Behavior Sequence Analysis method was applied to 39 participants’ detailed accounts of stalking written in online forums. The study provides illustration of the antecedents of stalking and how it may initiate and develop through to end of contact. Both stalker behavior and decisions made by victim were included in the models. The results show multiple patterns of stalkers’ behaviors; however, the results also clearly show that victims need not perform many behaviors for stalkers to continue with their actions. A main finding was how many behavior transitions occurred before victims felt a significant problem. A large number of participants indicated that they (repeatedly) reported their case of stalking to police and authorities; however, they were mostly dismissed or felt that police did not stop the stalker’s actions. A major implication of the current research is providing a novel method to produce a framework that may be used to operationalize definitions of stalking based on coherent frameworks of stalkers’ behaviors over time