ASUPAN LEMAK DAN KADAR NITRIC OXIDE PADA PENDERITA HIPERTENSI PRIMER DAN NORMOTENSI

Pola konsumsi tinggi lemak dapat berisiko tinggi terhadap kejadian hipertensi. Konsumsi lemak jenuh berlebihan dapat menimbulkan gangguan fungsi sel endotel pembuluh darah. Adanya kerusakan sel endotel ini kemudian menyebabkan penurunan kemampuan vasodilatasi dinding pembuluh darah sehingga terjadi peningkatan tekanan darah. Hal ini ditandai dengan penurunan kadar nitric oxide pada hipertensi. Penelitian ini bertujuan untuk menganalisis perbedaan asupan lemak dan kadar serum nitric oxide pada penderita hipertensi primer dan normotensi. Penelitian ini merupakan penelitian observasional analitik dengan rancangan cross sectional. Sampel penelitian terdiri dari 15 orang kelompok hipertensi primer dan 15 orang kelompok normal sebagai kelompok pembanding, berusia antara 40-70 tahun, dan yang mengunjungi Rumah Sakit Umum Haji Surabaya. Sampel dibagi secara acak. Pengumpulan data dilakukan melalui wawancara, food recall 2x24 jam dan pemeriksaan sampel darah. Kadar serum Nitric Oxide diukur dengan menggunakan metode ELISA (Enzyme-Linked Immunosorbent Assay). Data dianalisis dengan uji t-test independen. Hasil penelitian menunjukkan bahwa rata-rata tingkat konsumsi lemak lebih tinggi pada penderita hipertensi sedangkan kadar nitric oxide lebih rendah pada penderita hipertensi dibandingkan dengan subyek normal. Secara statistik terdapat perbedaan yang signifikan antara kedua kelompok mengenai kadar serum nitric oxide (p = 0,023) dan tingkat konsumsi lemak (p = 0,004). Kesimpulannya adalah ada perbedaan tingkat konsumsi lemak dan kadar serum nitric oxide antara penderita hipertensi primer dengan normotensi

KADAR ZINC, CUPRUM DAN SELENIUM PADA PENDERITA HIPERTENSI PRIMER DAN NORMOTENSI

One of the causes of primary hypertension is an exposure to free radicals. The formation of free radicals in the body can be prevented by taking antioxidants. The role of trace element such as zinc, cuprum and selenium is as a catalyst of antioxidant enzyme that are naturally present in the body. The objective of this study was to analyze the different of levels of zinc, cuprum and selenium in both normotensive and primary hypertension patients. This study was an analytical observational with cross sectional design. Samples were 15 primary hypertension patients and 15 normal individuals as a comparison group, aged between 40-70 years old, who visited Haji Hospital Surabaya. Samples were divided randomly. The data was collected through interviews, 2x24 hour food recall and examination of blood samples. Serum concentrations of Zinc, Cuprum and Selenium were measured by using AAS (Atomic Absorption Spectrophotometer) method. The data were analyzed by t-test independent test. The result of the study showed that the average levels of zinc, cuprum and selenium in hypertension patients were lower than the normotensive patients. However, statistically there was no difference found between the two groups regarding serum zinc levels (p=0.852) and there was a significant difference between the two groups regarding serum cuprum levels ( p=0.022) and serum selenium levels (p=0.014). The conclusion is there are different of levels of cuprum and selenium serum between the two groups but not with the levels of zinc

Decreased Effects of Hypertension Therapy Caused By Interaction Between Angiotensin Converting Enzyme Inhibitors (ACE-Inh) And Bananas

Prevalence of hypertension in Indonesia is quite high at 25.8%. Drug of choice for therapeutic treatment of hypertension is the class of Angiotensin Converting Enzyme Inhibitor. ACE-inhibitors can increase potassium that have a role in blood pressure regulation. Bananas are a source of high potassium. When ACE-inhibitors are consumed with bananas, interactions may occur and will lead to adverse drug reactions such as hyperkalemia and decreased effects of  blood  pressure  therapy.  This  study  aimed  to  investigate  the  interaction  of  bananas  with captopril and lisinopril against systolic and diastolic blood pressure in hypertensive rats. This was  an  experimental  study  with  pre  test-post  test  control  group  design.  Thirty  rats  were randomly  divided  into  6  groups,  without  treatment  (negative  control),  hypertension  (positive control),  hypertension  with  treatment  1  (captopril  2.25mg/kgBW  once  a  day),  hypertension with treatment 2 (lisinopril 0.6mg/kgBW once a day), hypertension with treatment 3 (captopril with banana) and hypertension  with treatment 4 (lisinopril with banana). Blood pressure  was measured  using  Non  Invasive  Blood  Pressure  technique  equipped  with  Non  Invasive  Blood Pressure  System  (CODA®)  at  before,  after  3  days  of  treatment.  Data  were analyzed  by  One Way  Anova.  The  results  showed  that  there  was  a  significant  difference  in  systolic  blood pressure  between    groups  and  there  was  no    difference  in  diastolic  blood  pressure  (p>0.05). Consumption of captopril or lisinopril along with bananas for 3 days can lower systolic blood pressure but not lower diastolic blood pressure

Perancangan Berkas Rekam Medis Kedokteran Gigi di Klinik Sakinah Kabupaten Jember

Gigi merupakan salah satu bagian tubuh manusia selain sidik jari dan golongan darah yang dapat digunakan sebagai sarana identifikasi dalam sebuah kasus kematian, khususnya bila rekaman tentang data gigi semasa hidup seseorang disimpan secara baik.1 Klinik Sakinah merupakan salah satu klinik di Kabupaten Jember yang memberikan pelayanan kesehatan gigi namun belum terdapat berkas rekam medis khusus untuk pelayanan gigi. Tujuan penelitian ini adalah untuk merancang berkas rekam medis kedokteran gigi di Klinik Sakinah Kabupaten Jember. Penelitian ini merupakan penelitian kualitatif, dimana peneliti menggali informasi tentang kebutuhan desain berkas rekam medik gigi berkaitan dengan aspek isi, penggunaan, dan ciri fisik. Kebutuhan desain berkas rekam medik gigi klinik Sakinah dikumpulkan melalui wawancara dengan subyek penelitian. Subjek penelitian berjumlah tiga orang yaitu pimpinan klinik Sakinah, dokter gigi, dan tenaga administrasi klinik Sakinah yang dipilih dengan teknik purposive sampling.. Perancangan berkas rekam medik gigi klinik Sakinah mengacu pada kebutuhan pengguna,aturan perancangan formulir, dan standar nasional rekam medis kedokteran gigi. Berkas rekam medik gigi klinik Sakinah berisi data pasien, kondisi umum pasien, odontogram, dan pemeriksaan. Desain berkas rekam medik gigi telah memenuhi kebutuhan pengguna baik aspek isi, penggunaan, dan ciri fisik Perlu dilakukan penyempurnaan pada data odontogram pada desain formulir rekam medis gigi sesuai dengan standar nasional rekam medis kedokteran gigi

ASUPAN MAKAN DAN PROFIL LIPID PEGAWAI DENGAN STATUS GIZI NORMAL DAN OBESITAS

Obesitas merupakan masalah gizi dan kesehatan kronis karena prevalensinya yang terus meningkat dan menjadi faktor risiko dari penyebab kematian ke-lima di dunia. Obesitas adalah suatu keadaan penumpukan lemak berlebihan atau abnormal yang dapat menimbulkan gangguan kesehatan. Salah satu penyebab terjadinya obesitas adalah asupan makan sehari-hari yang berlebihan. Obesitas yang terjadi dalam jangka waktu lama akan berdampak pada perubahan profil lipid seperti kolesterol total, LDL dan HDL. Penelitian ini bertujuan untuk mengetahui perbedaan asupan makan dan profil lipid pegawai dengan status gizi normal dan obesitas di Politeknik Negeri Jember. Jenis penelitian ini observasional analitik dengan desain studi cross sectional. Penelitian dilaksanakan di Politeknik Negeri Jember. Sampel penelitian adalah pegawai yang bekerja di Politenik Negeri Jember dan berstatus PNS yang berumur ≥ 30 tahun dan berjumlah 36 orang. Sampel dibagi kedalam dua kelompok yaitu status gizi normal dan obesitas. Teknik sampling dengan purposive sampling. Data asupan makan dikumpulkan dengan metode wawancara dan food recall, status gizi dengan pengukuran antropometri dan data profil lipid dengan pemeriksaan laboratorium. Data yang diperoleh dianalisis menggunakan Independent T-test dan Mann Whitney dengan signifikansi p = 0,05. Hasil penelitian ini menunjukkan tidak didapatkan perbedaan yang signifikan dari asupan karbohidrat (p= 0,203; p>0,05), protein (p= 0,303; p>0,05) dan serat (p= 0,481; p>0,05) pada kedua kelompok responden. Sedangkan, asupan energi (p=0,002; p<0,05) dan lemak (p=0,027; p<0,05) terdapat perbedaan yang signifikan antara responden dengan status gizi normal dan obesitas. Tidak didapatkan perbedaan kadar kolesterol total (p=0,351), LDL (p=0,173) dan HDL (p=0,250) antara kelompok dengan status gizi normal dan obesitas

Asupan Makan Dan Profil Lipid Pada Pegawai Dengan Status Gizi Obesitas Dan Status Gizi Normal

Obesitas merupakan masalah kesehatan kronis dan menjadi risiko penyebab kematian kelima di dunia. Obesitas merupakan keadaan penumpukan lemak berlebihan atau abnormal yang dapat menimbulkan gangguan kesehatan. Seseorang dikatakan obesitas dapat dilihat dari Indeks Masaa Tubuh > 25 kg/m2. Salah satu penyebab terjadinya obesitas adalah pola makan dan akan bermanifestasi pada perubahan profil lipid seperti kolesterol total, LDL dan HDL. Penelitian ini bertujuan untuk mengetahui perbedaan asupan makan dan profil lipid pegawai negeri sipil dengan status gizi normal dan obesitas di Politeknik Negeri Jember. Metode penelitian menggunakan observasional analitik dengan desain cross sectional. Sampel adalah PNS yang bekerja di Politenik Negeri Jember yang berumur ≥ 30 tahun dan berjumlah 38 orang. Teknik sampling dengan purposive sampling. Data dikumpulkan dengan metode wawancara, food recall, antropometri dan pemeriksaan laboratorium. Data yang diperoleh dianalisis menggunakan Independent T-test dan Mann Whitney. Hasil penelitian menunjukkan tidak didapatkan perbedaan yang signifikan dari asupan karbohidrat (p= 0,203; p>0,05), protein (p= 0,303; p>0,05) dan serat (p= 0,481; p>0,05) pada kedua kelompok responden. Asupan energi (p=0,002; p<0,05) dan lemak (p=0,027; p<0,05) memiliki perbedaan yang signifikan antara responden dengan status gizi normal dan obesitas. Tidak didapatkan perbedaan kadar kolesterol total (p=0,351), LDL (p=0,173) dan HDL (p=0,250) pada kelompok yang obesitas maupun status gizi normal

Pemberdayaan Komite Sekolah Dalam Menyediakan Jajanan (Snack) Sehat Dan Bergizi Bagi Siswa SDN Antirogo I Jember

Primary School children experience of rapid growth and development period that required an adequate food consumption for the balanced nutrition in according with the needs of children. Although breakfast remains a priority in child nutrition care. Snack for Primary School Children can be an alternative to sufficient the their nutritional needs who have not fulfilled from breakfast. The contribution of snack for primary school children to fulfill the daily nutritional adequacy should be between 15-20%. Students at SDN Antirogo I are commonly to consuming unhealthy snacks. There is no school effort to provided nutritious snacks. This devotional activity aims to enhance the role of school committees including of parents, teachers and canteen managers in providing safe, healthy and nutritious snacks in schools. Stages of the implementation of devotional activities was observation methods, interviews, discussions, counseling, practice, assistance and monitoring evaluation. The devotional activities was held four months with the aim of a school committee. The output were an increase of knowledge and understanding of healthy food snack for primary school children, commitment of PAZI team formation and module of healthy food snack guides

Effect of Antihipertensive Drugs And Banana (Musa Sp.) To Potassium Serum Levels of Hypertensive Wistar Rats Model

Consumption of antihypertensive drugs has the potential to cause drug and food interactions. Captopril/lisinopril can increase potassium levels by inhibiting the activity of renin angiotensin aldosterone. If captopril/lisinopril is consumed together with bananas, there is a risk of hyperkalemia because bananas are a high pottasium fruits. The aimed of this study was to determined the effect of captopril/lisinopril given with banana (Musa Sp) on potassium serum levels of Rattus novergicus strain Wistar hypertension model. This research was an experimental study with a randomized post-test control group design.Thirty (30) male wistar strain rats aged 2-3 months, weighing 200-250 grams were divided into 6 groups. The control group (K-) non-hypertensive rats, the control group (K+) hypertension rats+standard diet, the treatment group (P1) hypertension rats + standard diet + captopril 2.25 mg/kgBB, the treatment group (P2) hypertensive rats + standard diet + lisinopril 0.6 mg/kgBB, treatment group (P3) hypertension rats + standard diet + captopril with banana and treatment group (P4)  hypertension rats + standard diet + lisinopril with bananas. Measurement of potassium serum levels was carried out using electrolyte analyzer. Furthermore, the data were analyzed by One Way ANOVA test. The results showed that there were no significant differences in potassium serum levels between all groups. In conclusion, both of captopril 2.25 mg/kgBB and lisinopril 0.6 mg/kgBB given together with banana 9g/kgBB for 3 days hasn’t caused drug and food interactions. Keywords: banana fruits, captopril, lisinopril, potassium seru

Integrated Electronic Medical Record Design With Nutritional Screening System at NCC’s Teaching Factory

One of Politeknik Negeri Jember's Teaching Factories (TEFA) that offers community nutrition services is the Nutrition Care Centre (NCC). The design of electronic medical records (EMRs) for continuous care patients, especially those with non-communicable diseases, is being studied in order to meet the ever-increasing needs of health care, assist patients who require continuous care, and improve the way that modern medical technology serves humans. The Waterfall framework concept is used in the research process, and an electronic medical record system is designed in accordance with the goals and the overall architecture of the system. Black-box testing and white-box testing are then conducted to evaluate the features, dependability, and stability of the designed electronic medical record system. Furthermore, when combined with other research findings, the design's viability is demonstrated. It is evident that the electronic medical record system created for the study's patients who require ongoing care is entirely workable. As electronic medical records continue to develop, there will be more opportunities to research and enhance this system, which will benefit patients and hospitals alike in the long run

Zinc and Copper Levels in Patients with Primary Hypertension and Normotension

One of the causes of primary hypertension is an exposure to free radicals. The formation of free radicals in the body can be prevented by taking antioxidants. Zinc and copper are cofactors of endogenous antioxidant enzyme superoxide dismutase. This study aimed to analyze the differences of zinc and copper levels in primary hypertensive and normotensive patients. This was an analytical observational study with cross sectional design and simple random sampling method. Subjects were patients aged 40-70 years at Haji General Hospital consisting of 15 primary hypertensive patients and 15 normotensive individuals (comparison group). Data was collected through interviews and laboratory test of blood samples. Zinc and Copper serum concentrations were measured by AAS. Data were analyzed by chi-square and independent samples t-test. The results showed that the mean levels of zinc and copper in primary hypertensive patients was lower than normotensive. However, statistically there was no difference in zinc serum levels (p=0.852) in the two groups, and there was a significant difference in copper serum levels (p=0.032). It can be concluded that there were differences in copper serum levels between the two groups but not with the levels of zinc