MOBILE MAPPING FOR CULTURAL HERITAGE: THE SURVEY OF THE COMPLEX OF ST. JOHN OF THE HERMITS IN PALERMO (ITALY)

During the 11th and 12th century, the Arab-Norman architectural style characterized the most beautiful and important Cultural Heritage buildings in Sicily, and especially in Palermo (Italy). The relevance of these monuments is highlighted by their inclusion in the UNESCO World Heritage Sites List in 2015. For many years, the University of Palermo has been studying and documenting several Arab-Norman cultural assets, and in particular, the complex of St. John of the Hermits in Palermo (Italy). A first detailed 3D survey of the main structures of this complex was carried out using a terrestrial laser scanner while the 3D survey of the entire complex was made using a Mobile Mapping System (MMS). The paper describes the workflow and the results of the mobile mapping survey undertaken with a Handheld Mobile Laser Scanner (HMLS) based on Simultaneous Localisation and Mapping (SLAM) technologies. The work allowed surveying the entire site with an extremely fast acquisition and obtaining the geometric information useful for historical architectural valuations. In addition, due to the characteristics of the site, the work enabled the assessment of the HMLS data processing testing different automatic algorithms for point cloud filtering

Feasibility of Screening Programs for Domestic Violence in Pediatric and Child and Adolescent Mental Health Services: A Literature Review

Each year, 275 million children worldwide are exposed to domestic violence (DV) and suffer negative mental and physical health consequences; however, only a small proportion receive assistance. Pediatricians and child psychiatrists can play a central role in identifying threatened children. We reviewed experiences of DV screening in pediatric and child and adolescent mental health services (CAMHS) to understand its feasibility and provide clues for its implementation. We performed bibliographic research using the Sapienza Library System, PubMed, and the following databases: MEDLINE, American Psychological Association PsycArticles, American Psychological Association PsycInfo, ScienceDirect, and Scopus. We considered a 20-year interval when selecting the articles and we included studies published in English between January 2000 and March 2021. A total of 23 out of 2335 studies satisfied the inclusion criteria. We found that the prevalence of disclosed DV ranged from 4.2% to 48%, with most prevalence estimates between 10% and 20%. Disclosure increases with a detection plan, which is mostly welcomed by mothers (70-80% acceptance rates). Written tools were used in 55% of studies, oral interviews in 40%, and computer instruments in 20%. Mixed forms were used in three studies (15%). The most used and effective tool appeared to be the Conflict Tactics Scale (CTS) (30% of studies). For young children, parental reports are advisable and written instruments are the first preference; interviews can be conducted with older children. Our research pointed out that the current literature does not provide practical clinical clues on facilitating the disclosure in pediatric clinics and CAMHS. Further studies are needed on the inpatient population and in the field of children psychiatry

Cosmology with baryons: modelling the cosmic matter distribution for Large-Scale Structure analyses.

La interacción entre las fuerzas gravitatorias e hidrodinámicas en la formación de la estructura del Universo es compleja y aún se desconoce en gran medida. Las fuerzas gravitatorias son dominantes a gran escala, donde las perturbaciones de la densidad son pequeñas y, por tanto, se pueden describir mediante una teoría lineal. Sin embargo, en las escalas pequeñas surgen no linealidades y, por lo tanto, la teoría analítica no es suficiente. El gas es perturbado tanto por las fuerzas hidrodinámicas como por la gravedad, y tienen lugar varios procesos astrofísicos. La formación de galaxias desencadena explosiones de supernovas y la inyección de energía de los agujeros negros supermasivos que se acrecientan, perturbando la distribución de la masa y remodelando el potencial gravitatorio, lo que provoca posteriormente una reacción inversa en la materia oscura.La falta de una modelización precisa de estos procesos bariónicos es una de las principales fuentes de incertidumbre en los actuales estudios de lentes gravitatorias débiles, y se espera que su impacto aumente drásticamente en las próximas campañas de observación previstas.En esta tesis, queremos desarrollar un marco para modelar de forma consistente la distribución espacial y la evolución temporal de la materia oscura, el gas y las galaxias, en la Estructura a Gran Escala del Universo. Utilizamos un enfoque basado en simulaciones, variando simultáneamente la cosmología y los procesos astrofísicos. El núcleo de nuestro marco está dado por grandes simulaciones de alta resolución, que garantizan una modelización robusta de las no linealidades a pequeñas escalas, y predicciones precisas a grandes escalas. En una fase de posprocesamiento, desplazamos las partículas en nuestras simulaciones para explorar diferentes escenarios cosmológicos y bariónicos, mediante la combinación de dos algoritmos de última generación: el modelo de escalado cosmológico y el de corrección bariónica. Implementamos versiones extendidas y optimizadas de ambos algoritmos, para alcanzar la precisión requerida por los estudios de próxima generación, y los probamos sistemáticamente por separado y en combinación. Por último, utilizamos técnicas modernas de aprendizaje automático, y en concreto redes neuronales artificiales, entrenadas para aprender las conexiones entre los parámetros cosmológicos y astrofísicos y las estadísticas relevantes del campo de materia cósmica, tal y como se miden en nuestras simulaciones. De este modo, nuestras predicciones pueden realizarse con un coste computacional insignificante, y la contribución lineal, no lineal y bariónica puede calcularse por separado. Nuestros emuladores de redes neuronales están disponibles públicamente y pueden incorporarse fácilmente a una análisis de lentes gravitatorias débiles. Utilizando nuestro marco de trabajo, la modelización de la densidad cosmica puede extenderse a escalas pequeñas sin precedentes, de forma muy precisa y con una aceleración consistente en el tiempo de cálculo. Esperamos que las técnicas desarrolladas y los resultados presentados aquí sean útiles para una amplia gama de aplicaciones en los análisis de estructuras a gran escala, y en particular en studios de lentes gravitatorias débiles y galaxias.<br /

The Bacco Simulation Project: Bacco Hybrid Lagrangian Bias Expansion Model in Redshift Space

We present an emulator that accurately predicts the power spectrum of galaxies in redshift space as a function of cosmological parameters. Our emulator is based on a 2nd-order Lagrangian bias expansion that is displaced to Eulerian space using cosmological $N$-body simulations. Redshift space distortions are then imprinted using the non-linear velocity field of simulated particles and haloes. We build the emulator using a forward neural network trained with the simulations of the BACCO project, which covers an 8-dimensional parameter space including massive neutrinos and dynamical dark energy. We show that our emulator provides unbiased cosmological constraints from the monopole, quadrupole, and hexadecapole of a mock galaxy catalogue that mimics the BOSS-CMASS sample down to nonlinear scales ($k\sim0.6$[$h/$Mpc]$^{3}$). This work opens up the possibility of robustly extracting cosmological information from small scales using observations of the large-scale structure of the Universe.Comment: 16 pages, 9 figure

Sarcopenia Does Not Worsen Survival in Patients With Cirrhosis Undergoing Transjugular Intrahepatic Portosystemic Shunt for Refractory Ascites

INTRODUCTION: The impact of sarcopenia in patients undergoing transjugular intrahepatic portosystemic shunt (TIPSS) insertion for refractory ascites is unknown. METHODS: All adult patients who underwent TIPSS insertion for refractory ascites between 2010 and 2018 were included. Skeletal muscle index at L3 was used to determine sarcopenia status. RESULTS: One hundred seven patients were followed for 14.2 months. Sarcopenia was present in 57% of patients. No patient had history of pre-TIPSS hepatic encephalopathy (HE). De novo HE occurred in 30% of patients. On multivariate analysis, only platelet count and L3-SMI predicted de novo HE. On multivariate analysis, age and model for end-stage liver disease with sodium predicted mortality, whereas L3-SMI and sarcopenia did not. In patients with repeat imaging, L3-SMI improved significantly post-TIPSS compared with baseline. DISCUSSION: Sarcopenia should not be considered as a contraindication to TIPSS insertion in refractory ascites because it is not associated with de novo HE or increased mortality

A systematic review of the risk factors for clinical response to opioids for all-age patients with cancer-related pain and presentation of the paediatric STOP pain study

Inter-patient variability in response to opioids is well known but a comprehensive definition of its pathophysiological mechanism is still lacking and, more importantly, no studies have focused on children. The STOP Pain project aimed to evaluate the risk factors that contribute to clinical response and adverse drug reactions to opioids by means of a systematic review and a clinical investigation on paediatric oncological patients

Genetic predisposition to hemophagocytic lymphohistiocytosis: report on 500 patients from the Italian registry

Background Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease affecting mostly children but also adults and characterized by hyperinflammatory features. A subset of patients, referred to as having familial hemophagocytic lymphohistiocytosis (FHL), have various underlying genetic abnormalities, the frequencies of which have not been systematically determined previously. Objective This work aims to further our understanding of the pathogenic bases of this rare condition based on an analysis of our 25 years of experience. Methods From our registry, we have analyzed a total of 500 unselected patients with HLH. Results Biallelic pathogenic mutations defining FHL were found in 171 (34%) patients; the proportion of FHL was much higher (64%) in patients given a diagnosis during the first year of life. Taken together, mutations of the genes PRF1 (FHL2) and UNC13D (FHL3) accounted for 70% of cases of FHL. Overall, a genetic diagnosis was possible in more than 90% of our patients with FHL. Perforin expression and the extent of degranulation have been more useful for diagnosing FHL than hemophagocytosis and the cytotoxicity assay. Of 281 (56%) patients classified as having "sporadic" HLH, 43 had monoallelic mutations in one of the FHL-defining genes. Given this gene dosage effect, FHL is not strictly recessive. Conclusion We suggest that the clinical syndrome HLH generally results from the combined effects of an exogenous trigger and genetic predisposition. Within this combination, different weights of exogenous and genetic factors account for the wide disease spectrum that ranges from HLH secondary to severe infection to FHL

Investigation of a Pt3Sn/C Electro-Catalyst in a Direct Ethanol Fuel Cell Operating at Low Temperatures for Portable Applications

A 20% Pt3Sn/C catalyst was prepared by reduction with formic acid and used in a direct ethanol fuel cell at low temperatures. The electro-catalytic activity of this bimetallic catalyst was compared to that of a commercial 20% Pt/C catalyst. The PtSn catalyst showed better results in the investigated temperature range (30 degrees-70 degrees C). Generally, Sn promotes ethanol oxidation by adsorption of OH species at considerably lower potentials compared to Pt, allowing the occurrence of a bifunctional mechanism. The bimetallic catalyst was physico-chemically characterized by X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) analyses. The presence of SnO2 in the bulk and surface of the catalyst was observed. It appears that SnO2 can enhance the ethanol electro-oxidation activity at low potentials due to the supply of oxygen-containing species for the oxidative removal of CO and CH3CO species adsorbed on adjacent Pt active sites.Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES