Determinan Ketidakpatuhan Terapi Antiretroviral pada ODHA Dewasa

Determinants of non-adherence to antiretroviral therapy in adults with HIV/AIDSPurposeThis study aimed to determine the factors of non-adherence ARV therapy in adult PLWHA.MethodsA case-control study was conducted using secondary data of the Cilacap VCT clinic with consecutive sampling technique. The total sample was 204, consisting of 102 cases and 102 controls (1:1). The cases were adult PLWHA who did not adhere to ARV therapy and the controls were adult PLWHA who adhere to ARV therapy. The bivariate analysis used Chi-square and Fisher's exact tests and multivariate analysis used logistic regression tests. ResultsThe variables that were shown to jointly affect non-adherence to ARV therapy in adult PLWHA were the level of education, CD4 count, PMO and opportunistic infections.ConclusionsThe risk factors of non-adherence to ARV therapy in adult PLWHA were the level of education, PMO, CD4 count and opportunistic infections. There needs to be a special assistance and counseling program on a regular basis to PLWHA adults with low education, obligating all PLWHA adults that start ARV therapy to have a PMO, continue HIV screening programs to entire population at risk and advocate the local governments to facilitate PLWHA who can not afford to obtain CD4 test

Faktor Risiko Kematian Akibat Dengue di Rumah Sakit Sardjito YOGYAKARTA

Risk factors of death due to dengue hemorrhagic fever in a tertiary public teaching hospital of YogyakartaPurposeWe examined risk factors of dengue hemorrhagic fever death in Dr. Sardjito Hospital.MethodWe conducted a case control study from patient medical records and interviews with parents.ResultsWe found 29 deaths and 58 patients who survived. The probability of death among obese children was 6 times higher than non obese children and the probability of death in children with prolonged shock was 12 times higher than children without prolonged shock. Other variables were family occupation, family income, residential zones, transportation, treatment financing, accuracy of diagnosis in previous health facilities, and fluid resuscitation before being referred had no significant relationship with dengue mortality.ConclusionObesity and prolonged shock were risk factors of dengue hemorrhagic fever death in children. Improved education to parents about high risk of shock syndrome among patients is needed especially for obese children. Further studies related to social determinants in dengue hemorrhagic fever death are also necessary