Perceptions of Domestic Violence: Leaving vs. Staying in Abusive Relationships

This study examined whether participants’ attributions of blame and responsibility toward a victim of domestic violence were influenced by whether or not the victim left her abuser. It also looked at whether or not educational information regarding the difficulties of leaving a violent partner would affect these attributions. Participants, all adults from the United States, either read a vignette in which a woman victim of domestic violence stayed with her abusive husband, or left him. Prior to reading the vignette, some participants were given information about the problems associated with leaving a violent partner, and some were not. All participants completed a scale measuring victim blame. No main effects of whether the victim left or whether the participant received information were found on attributions of blame, and there was not a statistically significant interaction between the victim leaving and presence of information. An interaction between whether or not the participant was a victim of domestic violence and the presence of information was found on victim blame, but further research should examine this more closely with a study specifically designed to investigate victims and their perceptions

Women’s Sexual Satisfaction in the Context of Midlife Relationships: Examining an Ecological Model and Intergenerational Caregiving

This study examined an ecological model of sexual satisfaction in midlife women in relationships, and paid particular attention to the role of intergenerational caregiving in predicting satisfaction. Participants were 1,411 midlife women in relationships who participated in the Midlife in the United States (MIDUS) national study. Using split samples for replication purposes, data from this survey were examined to test the hypothesis that an ecological model - including the macrosystem level variable of religiosity, the exosystem level variables of SES, social support, and parenthood, the mesosystem level variables of relationship satisfaction, affectual solidarity, relationship length, and sexual functioning, and the microsystem level variables of age, negative affect, and physical health and functioning – would together predict sexual satisfaction. This study also hypothesized that family caregiving status, and specifically being an intergenerational caregiver, would add to the predictive power of the existing model, with caregiving associated with decreased satisfaction. Further, this study hypothesized that the extent of the intergenerational caregiving role would be negatively associated with sexual satisfaction, above and beyond caregiving status. Finally, this study hypothesized that the relationship between extent of intergenerational caregiving and sexual satisfaction would be moderated by perceived partner support, and that this relationship would be mediated by levels of negative affect. Support for an ecological model of sexual satisfaction was found, with income, affectual solidarity, and sexual function significantly contributing to sexual satisfaction across both split samples. However, caregiver status was not associated with sexual satisfaction and did not add any predictive power to the existing ecological model. Taken together, results suggest that an ecological model is a relevant organizing framework for understanding sexual satisfaction in this population of women

Celiac disease in pediatric patients according to HLA genetic risk classes: a retrospective observational study

Background: Celiac disease (CD) is an autoimmune enteropathy in which HLA-DQ haplotypes define susceptibility. Our aim was to evaluate if belonging to a certain HLA-DQ class risk could be associated to the clinical, serological and histological presentation of CD. Methods: We performed a retrospective observational monocentric study including all 300 patients diagnosed with CD, who underwent HLA typing. Clinical, serological and histological data was collected from clinical records and their association with HLA-DQ class risk was verified through statistical tests. Results: In our sample mean age at onset was 6.7 ± 4.2 years, with a prevalence of females (n = 183; 61%), typical symptoms (n = 242; 80.6%) and anti-tTG IgA ≥ 100 U/mL (n = 194; 64.7%). Family history was present only in 19% (n = 57) of patients, and it was not significantly associated with any of the clinical and demographical data analyzed or the belonging to a certain HLA-DQ class risk. We found in the male population more frequently a coexistence of CD and atopic syndrome (males: n = 47; 40.2%; females: n = 50; 27.3%; p = 0.020). Early age of onset, instead, was associated with typical symptoms (m = 6.4 ± 4; p = 0.045) and elevated liver enzymes (m = 5 ± 3.8; p < 0.001), while later age of onset was associated with presence of other autoimmune diseases (m = 8.2 ± 4; p = 0.01). We observed statistically significant influences of HLA class risk on antibodies and liver enzymes levels: G1, G4 and G2 classes showed more frequently anti-tTG IgA ≥ 100 U/mL (n = 44; 80%, n = 16; 69.6%, n = 48; 67.6% respectively; p-value = 0.037), and in patients from G2 class we found enhanced liver enzymes (n = 28; 39.4%; p-value = 0.005). HLA class risk was still significantly associated with anti-tTG ≥ 100 (p = 0.044) and with hypertransaminasemia (p = 0.010) after a multiple logistic regression adjusted for the effect of gender, age at onset and family history. Conclusions: We failed to prove an association between HLA-DQ genotypes and the clinical features in our CD pediatric patients. Although, our results suggest an effect of the DQB1–02 allele not only on the level of antibodies to tTG, but possibly also on liver involvement

Do trauma cue exposure and/or PTSD symptom severity intensify selective approach bias toward cannabis cues in regular cannabis users with trauma histories?

Trauma cue-elicited activation of automatic cannabis-related cognitive biases are theorized to contribute to comorbid posttraumatic stress disorder and cannabis use disorder. This phenomenon can be studied experimentally by combining the trauma cue reactivity paradigm (CRP) with cannabis-related cognitive processing tasks. In this study, we used a computerized cannabis approach-avoidance task (AAT) to assess automatic cannabis (vs. neutral) approach bias following personalized trauma (vs. neutral) CRP exposure. We hypothesized that selective cannabis (vs. neutral) approach biases on the AAT would be larger among participants with higher PTSD symptom severity, particularly following trauma (vs. neutral) cue exposure. We used a within-subjects experimental design with a continuous between-subjects moderator (PTSD symptom severity). Participants were exposed to both a trauma and neutral CRP in random order, completing a cannabis AAT (cannabis vs. neutral stimuli) following each cue exposure. Current cannabis users with histories of psychological trauma (n = 50; 34% male; mean age = 37.8 years) described their most traumatic lifetime event, and a similarly-detailed neutral event, according to an established interview protocol that served as the CRP. As hypothesized, an AAT stimulus type x PTSD symptom severity interaction emerged (p = .042) with approach bias greater to cannabis than neutral stimuli for participants with higher (p = .006), but not lower (p = .36), PTSD symptom severity. Contrasting expectations, the stimulus type x PTSD symptoms effect was not intensified by trauma cue exposure (p = .19). Selective cannabis approach bias may be chronically activated in cannabis users with higher PTSD symptom severity and may serve as an automatic cognitive mechanism to help explain PTSD-CUD co-morbidity.</p